Email l.a.kelley@imperial.ac.uk Description A1A535 Date Wed Jul 10 14:03:03 BST 2013 Unique Job ID 671d1baf5f3b7c66

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2lulA_ 99.3 18 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase tec; PDBTitle: solution nmr structure of ph domain of tyrosine-protein kinase tec2 from homo sapiens, northeast structural genomics consortium (nesg)3 target hr3504c 2 c2dtcB_ 99.3 23 PDB header:protein binding Chain: B: PDB Molecule:ral guanine nucleotide exchange factor ralgps1a; PDBTitle: crystal structure of ms0666 3 d1baka_ 99.2 13 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 4 d2bcja2 99.2 19 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 5 d1btka_ 99.2 18 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 6 d1x1fa1 99.2 18 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 7 c2q13A_ 99.1 22 PDB header:protein transport Chain: A: PDB Molecule:dcc-interacting protein 13 alpha; PDBTitle: crystal structure of bar-ph domain of appl1 8 c2dhkA_ 99.1 20 PDB header:immune system Chain: A: PDB Molecule:tbc1 domain family member 2; PDBTitle: solution structure of the ph domain of tbc1 domain family2 member 2 protein from human 9 c2d9xA_ 99.1 14 PDB header:lipid transport Chain: A: PDB Molecule:oxysterol binding protein-related protein 11; PDBTitle: solution structure of the ph domain of oxysterol binding2 protein-related protein 11 from human 10 d1u5fa1 99.0 24 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 11 c3cxbB_ 99.0 20 PDB header:signaling protein Chain: B: PDB Molecule:pleckstrin homology domain-containing family m PDBTitle: crystal structure of sifa and skip 12 c2d9wA_ 98.9 23 PDB header:signaling protein Chain: A: PDB Molecule:docking protein 2; PDBTitle: solution structure of the ph domain of docking protein 22 from human 13 d1u5da1 98.9 18 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 14 c3a8qB_ 98.9 28 PDB header:signaling protein Chain: B: PDB Molecule:t-lymphoma invasion and metastasis-inducing PDBTitle: low-resolution crystal structure of the tiam2 phccex domain 15 c2kcjA_ 98.9 18 PDB header:membrane protein Chain: A: PDB Molecule:pleckstrin homology domain-containing family a PDBTitle: solution structure of fapp1 ph domain 16 c2yryA_ 98.9 23 PDB header:signaling protein Chain: A: PDB Molecule:pleckstrin homology domain-containing family a PDBTitle: solution structure of the ph domain of pleckstrin homology2 domain-containing family a member 6 from human 17 c4h8sA_ 98.9 24 PDB header:signaling protein Chain: A: PDB Molecule:dcc-interacting protein 13-beta; PDBTitle: crystal structure of human appl2barph domain 18 c3nsuA_ 98.9 20 PDB header:signaling protein Chain: A: PDB Molecule:phosphatidylinositol 4,5-bisphosphate-binding protein slm1; PDBTitle: a systematic screen for protein-lipid interactions in saccharomyces2 cerevisiae 19 c2d9zA_ 98.8 22 PDB header:signaling protein Chain: A: PDB Molecule:protein kinase c, nu type; PDBTitle: solution structure of the ph domain of protein kinase c, nu2 type from human 20 c1u5fA_ 98.8 22 PDB header:signaling protein Chain: A: PDB Molecule:src-associated adaptor protein; PDBTitle: crystal structure of the ph domain of skap-hom with 8 vector-derived2 n-terminal residues 21 d1wgqa_ not modelled 98.8 16 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 22 c2dn6A_ not modelled 98.8 24 PDB header:signaling protein Chain: A: PDB Molecule:kiaa0640 protein; PDBTitle: solution structure of the ph domain of kiaa0640 protein2 from human 23 d1wi1a_ not modelled 98.8 20 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 24 d1v5ua_ not modelled 98.8 24 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 25 c2rloA_ not modelled 98.8 19 PDB header:signaling protein Chain: A: PDB Molecule:centaurin-gamma 1; PDBTitle: split ph domain of pi3-kinase enhancer 26 d1v5pa_ not modelled 98.8 25 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 27 d1w1ha_ not modelled 98.8 20 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 28 d1unqa_ not modelled 98.8 24 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 29 c3tfmA_ not modelled 98.7 17 PDB header:motor protein Chain: A: PDB Molecule:myosin x; PDBTitle: myosin x ph1n-ph2-ph1c tandem 30 c2da0A_ not modelled 98.7 19 PDB header:signaling protein Chain: A: PDB Molecule:130-kda phosphatidylinositol 4,5-biphosphate- PDBTitle: solution structure of the ph domain of pip2-dependent arf12 gtpase-activating protein from human 31 c2rsgA_ not modelled 98.7 19 PDB header:lipid transport Chain: A: PDB Molecule:collagen type iv alpha-3-binding protein; PDBTitle: solution structure of the cert ph domain 32 c2dkpA_ not modelled 98.7 21 PDB header:signaling protein Chain: A: PDB Molecule:pleckstrin homology domain-containing family a PDBTitle: solution structure of the ph domain of pleckstrin homology2 domain-containing protein family a member 5 from human 33 c2lkoA_ not modelled 98.7 14 PDB header:cell adhesion Chain: A: PDB Molecule:fermitin family homolog 2; PDBTitle: structural basis of phosphoinositide binding to kindlin-2 pleckstrin2 homology domain in regulating integrin activation 34 c2r09A_ not modelled 98.7 21 PDB header:signaling protein Chain: A: PDB Molecule:cytohesin-3; PDBTitle: crystal structure of autoinhibited form of grp1 arf gtpase exchange2 factor 35 d1wjma_ not modelled 98.7 29 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 36 d1v88a_ not modelled 98.7 17 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 37 d2coaa1 not modelled 98.7 23 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 38 c3a8nA_ not modelled 98.7 27 PDB header:signaling protein Chain: A: PDB Molecule:t-lymphoma invasion and metastasis-inducing PDBTitle: crystal structure of the tiam1 phccex domain 39 c2j59O_ not modelled 98.7 22 PDB header:hydrolase Chain: O: PDB Molecule:rho-gtpase activating protein 10; PDBTitle: crystal structure of the arf1:arhgap21-arfbd complex 40 d1eaza_ not modelled 98.7 25 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 41 d1plsa_ not modelled 98.7 21 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 42 d2elba2 not modelled 98.7 23 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 43 d2i5fa1 not modelled 98.6 21 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 44 c3pp2A_ not modelled 98.6 24 PDB header:hydrolase activator Chain: A: PDB Molecule:rho gtpase-activating protein 27; PDBTitle: crystal structure of the pleckstrin homology domain of arhgap27 45 d1u5ea1 not modelled 98.6 24 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 46 d1wg7a_ not modelled 98.6 21 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 47 d1p6sa_ not modelled 98.6 23 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 48 d2j59m1 not modelled 98.6 27 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 49 c2ys3A_ not modelled 98.6 16 PDB header:signaling protein Chain: A: PDB Molecule:unc-112-related protein 2; PDBTitle: solution structure of the ph domain of kindlin-3 from human 50 d2fjla1 not modelled 98.6 15 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 51 c2rovA_ not modelled 98.6 19 PDB header:transferase Chain: A: PDB Molecule:rho-associated protein kinase 2; PDBTitle: the split ph domain of rock ii 52 d1upqa_ not modelled 98.5 22 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 53 d2coca1 not modelled 98.5 16 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 54 d2coda1 not modelled 98.5 17 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 55 c4f7hA_ not modelled 98.5 17 PDB header:cell adhesion Chain: A: PDB Molecule:fermitin family homolog 2; PDBTitle: the crystal structure of kindlin-2 pleckstrin homology domain in free2 form 56 c1faoA_ not modelled 98.5 26 PDB header:signaling protein Chain: A: PDB Molecule:dual adaptor of phosphotyrosine and 3- PDBTitle: structure of the pleckstrin homology domain from2 dapp1/phish in complex with inositol 1,3,4,5-3 tetrakisphosphate 57 d1faoa_ not modelled 98.5 26 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 58 c4bbkA_ not modelled 98.5 17 PDB header:cell adhesion Chain: A: PDB Molecule:fermitin family homolog 1; PDBTitle: structural and functional characterisation of the kindlin-12 pleckstrin homology domain 59 c4gzuB_ not modelled 98.5 23 PDB header:signaling protein Chain: B: PDB Molecule:ferm, rhogef and pleckstrin domain-containing protein 2; PDBTitle: crystal strucure of the dh-ph-ph domain of farp2 60 c3fehA_ not modelled 98.4 19 PDB header:hydrolase activator Chain: A: PDB Molecule:centaurin-alpha-1; PDBTitle: crystal structure of full length centaurin alpha-1 61 c2p0fA_ not modelled 98.4 20 PDB header:ligand binding protein Chain: A: PDB Molecule:rho gtpase-activating protein 9; PDBTitle: arhgap9 ph domain in complex with ins(1,3,5)p3 62 d1fgya_ not modelled 98.4 22 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 63 d1v89a_ not modelled 98.4 25 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 64 c2d9vA_ not modelled 98.4 14 PDB header:membrane protein Chain: A: PDB Molecule:pleckstrin homology domain-containing protein PDBTitle: solution structure of the ph domain of pleckstrin homology2 domain-containing protein family b member 1 from mouse 65 d1qqga1 not modelled 98.4 18 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Phosphotyrosine-binding domain (PTB) 66 c2dhiA_ not modelled 98.4 17 PDB header:signaling protein Chain: A: PDB Molecule:pleckstrin homology domain-containing family b PDBTitle: solution structure of the ph domain of evectin-2 from mouse 67 d1u29a1 not modelled 98.4 21 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 68 d1btna_ not modelled 98.3 23 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 69 d1x1ga1 not modelled 98.3 18 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 70 c2y7bA_ not modelled 98.3 19 PDB header:cell cycle Chain: A: PDB Molecule:actin-binding protein anillin; PDBTitle: crystal structure of the ph domain of human actin-binding2 protein anillin anln 71 c1qqgA_ not modelled 98.2 20 PDB header:signal transduction Chain: A: PDB Molecule:insulin receptor substrate 1; PDBTitle: crystal structure of the ph-ptb targeting region of irs-1 72 d1droa_ not modelled 98.2 17 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 73 c3hk0B_ not modelled 98.2 21 PDB header:signaling protein Chain: B: PDB Molecule:growth factor receptor-bound protein 10; PDBTitle: crystal structure of the ra and ph domains of grb10 74 d2cofa1 not modelled 98.2 19 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 75 c4gmvB_ not modelled 98.2 23 PDB header:cell adhesion Chain: B: PDB Molecule:ras-associated and pleckstrin homology domains-containing PDBTitle: crystal structure of the coiled-coil, ra and ph domains of2 lamellipodin 76 d1ki1b2 not modelled 98.2 23 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 77 d2dyna_ not modelled 98.1 18 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 78 c2k2jA_ not modelled 98.1 21 PDB header:hydrolase, signaling protein Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate PDBTitle: nmr solution structure of the split ph domain from2 phospholipase c gamma 2 79 c3o96A_ not modelled 98.1 23 PDB header:transferase Chain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor 80 d1xx0a1 not modelled 98.1 24 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 81 c3tcaA_ not modelled 98.0 19 PDB header:signaling protein Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding family b member PDBTitle: crystal structure of the ras-associating and pleckstrin-homology2 domains of riam 82 c4h6yA_ not modelled 97.9 27 PDB header:signaling protein Chain: A: PDB Molecule:ferm, rhogef and pleckstrin domain-containing protein 1; PDBTitle: crystal strucure of the dh-ph-ph domain of farp1 83 c1w63A_ 97.8 11 PDB header:endocytosis Chain: A: PDB Molecule:adapter-related protein complex 1 gamma 1 PDBTitle: ap1 clathrin adaptor core 84 d1gw5b_ 97.6 14 Fold:alpha-alpha superhelix Superfamily:ARM repeat Family:Clathrin adaptor core protein 85 c3ml4D_ not modelled 97.5 19 PDB header:signaling protein Chain: D: PDB Molecule:protein dok-7; PDBTitle: crystal structure of a complex between dok7 ph-ptb and the musk2 juxtamembrane region 86 d2dfka2 not modelled 97.4 18 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 87 c2db0B_ 97.4 12 PDB header:protein binding Chain: B: PDB Molecule:253aa long hypothetical protein; PDBTitle: crystal structure of ph0542 88 d1rj2a2 not modelled 97.3 17 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 89 d1maia_ not modelled 97.3 21 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 90 d1v61a_ not modelled 97.2 17 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 91 c2jkrL_ 97.0 12 PDB header:endocytosis Chain: L: PDB Molecule:ap-2 complex subunit alpha-2; PDBTitle: ap2 clathrin adaptor core with dileucine peptide rm(2 phosphos)qikrllse 92 c2lg1A_ 97.0 16 PDB header:metal binding protein Chain: A: PDB Molecule:a-kinase anchor protein 13; PDBTitle: solution structure of the human akap13 ph domain and stabilizing dh2 helix 93 d1ntya2 not modelled 96.5 16 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 94 d1zc3b1 not modelled 96.4 16 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 95 d1xcga2 not modelled 96.4 23 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 96 c3odwB_ not modelled 96.3 13 PDB header:signaling protein Chain: B: PDB Molecule:rho guanine nucleotide exchange factor 1; PDBTitle: crystal structure of the linker-dh/ph domains of p115-rhogef 97 c3mpxA_ not modelled 96.3 21 PDB header:lipid binding protein Chain: A: PDB Molecule:fyve, rhogef and ph domain-containing protein 5; PDBTitle: crystal structure of the dh and ph-1 domains of human fgd5 98 c3bjiA_ not modelled 96.2 19 PDB header:signaling protein Chain: A: PDB Molecule:proto-oncogene vav; PDBTitle: structural basis of promiscuous guanine nucleotide exchange2 by the t-cell essential vav1 99 c3ky9B_ not modelled 96.1 23 PDB header:apoptosis Chain: B: PDB Molecule:proto-oncogene vav; PDBTitle: autoinhibited vav1 100 c2vszA_ not modelled 96.0 23 PDB header:apoptosis Chain: A: PDB Molecule:engulfment and cell motility protein 1; PDBTitle: crystal structure of the elmo1 ph domain 101 c3qwmA_ not modelled 95.9 15 PDB header:signaling protein Chain: A: PDB Molecule:iq motif and sec7 domain-containing protein 1; PDBTitle: crystal structure of gep100, the plextrin homology domain of iq motif2 and sec7 domain-containing protein 1 isoform a 102 c2vrwB_ not modelled 95.9 23 PDB header:signaling protein Chain: B: PDB Molecule:proto-oncogene vav; PDBTitle: critical structural role for the ph and c1 domains of the2 vav1 exchange factor 103 d1dbha2 not modelled 95.6 27 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 104 d1kz7a2 not modelled 95.5 20 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 105 c1x86A_ not modelled 95.1 18 PDB header:signaling protein/membrane protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 12; PDBTitle: crystal structure of the dh/ph domains of leukemia-associated rhogef2 in complex with rhoa 106 c2dfkA_ not modelled 95.0 19 PDB header:cell cycle Chain: A: PDB Molecule:collybistin ii; PDBTitle: crystal structure of the cdc42-collybistin ii complex 107 c3w3zA_ not modelled 95.0 13 PDB header:protein transport/nuclear protein Chain: A: PDB Molecule:importin subunit beta-3; PDBTitle: crystal structure of kap121p bound to rangtp 108 c3odxA_ not modelled 95.0 14 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 1; PDBTitle: crystal structure of an n-terminally truncated linker-dh/ph domains of2 p115-rhogef 109 c3a98B_ not modelled 94.7 23 PDB header:signaling protein Chain: B: PDB Molecule:engulfment and cell motility protein 1; PDBTitle: crystal structure of the complex of the interacting regions of dock22 and elmo1 110 c1ki1B_ not modelled 94.3 19 PDB header:signaling protein Chain: B: PDB Molecule:intersectin long form; PDBTitle: guanine nucleotide exchange region of intersectin in2 complex with cdc42 111 c1xcgA_ not modelled 94.2 19 PDB header:signaling protein activator/signaling pr Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 11; PDBTitle: crystal structure of human rhoa in complex with dh/ph2 fragment of pdzrhogef 112 d1txda2 not modelled 93.5 22 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 113 c3v6aA_ not modelled 92.0 20 PDB header:apoptosis inhibitor Chain: A: PDB Molecule:apoptosis inhibitor 5; PDBTitle: helical repeat structure of apoptosis inhibitor 5 reveals protein-2 protein interaction modules 114 c3ohmB_ not modelled 91.5 15 PDB header:signaling protein / hydrolase Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase PDBTitle: crystal structure of activated g alpha q bound to its effector2 phospholipase c beta 3 115 d1omwa2 not modelled 91.3 20 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 116 c2nppE_ not modelled 89.6 18 PDB header:hydrolase/hydrolase inhibitor Chain: E: PDB Molecule:serine/threonine-protein phosphatase 2a 56 kda regulatory PDBTitle: structure of the protein phosphatase 2a holoenzyme 117 d2nppb1 not modelled 89.6 18 Fold:alpha-alpha superhelix Superfamily:ARM repeat Family:B56-like 118 d2bpta1 not modelled 89.5 7 Fold:alpha-alpha superhelix Superfamily:ARM repeat Family:Armadillo repeat 119 c2rgnB_ not modelled 88.8 16 PDB header:signaling protein complex Chain: B: PDB Molecule:rhoa/rac/cdc42 exchange factor; PDBTitle: crystal structure of p63rhogef complex with galpha-q and rhoa 120 c3qr0A_ not modelled 88.7 16 PDB header:hydrolase Chain: A: PDB Molecule:phospholipase c-beta (plc-beta); PDBTitle: crystal structure of s. officinalis plc21