|   |   |
28 | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
I | E | D | S | L | T | E | A | L | E | Q | I | K | V | I | S | S | S | L | D | Y | Q | T | N | N | N | D | Q | A | V | V | E | I | C | I | T | R | I | T | T | A | I | R | E | T | E | S | I | E | K | H | A | R | A | L | V | G | L | W | D |
| Query Conservation |   |
|   |   |
|
|
|   |   |
|   |   |
|   |   |
|   |   |   |
|
|
|   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|   |   |
|
|
|   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
L | S | S | S | F | E | L | I | V | Q | K | L | L | E | T | T | D | R | P | D | . |
. |
. |
. |
G | H | Q | N | N | L | R | S | S | A | Y | E | S | L | M | E | I | V | K | N | S | A | . |
. |
K | D | C | Y | P | A | V | Q | K | T | T | L |
| Template Known Secondary structure |   |
T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| T | T | . | . | . | . | T | T | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
| . | . | G | G | G |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
499 | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | |
|
|
|
. | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | |
|
. | . | . | . | . | . | . | . | . | 550 | . | . |
|   |
|   |   |
88 | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 140 | . | . |
| Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |  |
|
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
| Query Sequence |   |
S | C | L | E | H | N | L | R | P | A | G | K | D | E | D | T | P | H | A | K | I | A | S | D | I | M | S | C | I | L | Q | N | Y | N | R | T | P | V | M | V | L | A | V | P | I | A | V | K | F | L | . |
. |
. |
. |
. |
H | R | G | S | K |
| Query Conservation |   |
|
|
|   |
|   |
|   |
|   |   |
|
|   |
|   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|   |
|
|   |
|   |   |
|
|   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |   |   |
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |
|   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
| Template Sequence |   |
V | I | M | E | R | L | Q | Q | V | L | . |
. |
Q | M | F | N | D | L | Q | S | L | L | C | A | T | L | Q | N | V | L | R | K | V | Q | H | Q | D | A | L | Q | I | S | D | V | V | M | A | S | L | L | R | M | F | Q | S | T | A | G | S | G |
| Template Known Secondary structure |   |
 |  |  |  | T |  |  |  |  |  | . | . | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
| . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
553 | . | . | . | . | . | . | 560 | . | . | |
|
. | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 |
|   |
|   |   |
143 | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 190 | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | L | C | R | N | M | S | N | Y | L | S | L | A | A | I | T | K | A | D | L | L | A | D | H | T | E | G | I | I | K | S | I | L | Q | G | N | A | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
L | L | R | V | L | P | A | V | Y | E | K | Q | P |
| Query Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |
|
|
|   |
|   |   |   |
|
|   |
|
|
|   |
|
|   |   | . | . | . | . | . | . | . | . | . |
|   |
|
|
|
|   |
|
|   |   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
| Template Sequence |   |
G | V | Q | E | D | A | L | M | A | V | S | T | L | V | E | V | L | G | G | E | F | L | K | Y | M | E | A | F | K | P | F | L | G | I | G | L | K | N | Y | A | E | Y | Q | V | C | L | A | A | V | G | L | V | G | D | L | C | R | A | L | Q |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G | G | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | G |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
623 | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . |
|   |
|   |   |
194 | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | |
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Q | P | I | N | R | H | L | A | E | L | L | A | L | M | S | Q | L | . |
. |
. |
. |
. |
. |
E | Q | T | E | Q | Y | H | L | L | R | L | L | H | V | A | A | K | R | K | D | V | E | V | V | Q | K | C | V | P | F | L | I | R | N | L | K | D |
| Query Conservation |   |
|
|
|   |   |
|   |   |   |
|
|   |
|
|
|   |   | . | . | . | . | . | . |
|   |   |
|   |
|   |
|
|
|
|   |   |
|
|
|
|   |
|
|   |   |   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
| Template Sequence |   |
S | N | I | I | P | F | C | D | E | V | M | Q | L | L | L | E | N | L | G | N | E | N | V | H | R | S | V | K | P | Q | I | L | S | V | F | G | D | I | A | L | A | I | G | . |
G | E | F | K | K | Y | L | E | V | V | L | N | T | L | Q | Q |
| Template Known Secondary structure |   |
G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | . | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
683 | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | |
. | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . |
|   |
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
248 | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 270 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | T | Y | N | D | I | I | L | N | I | L | I | E | I | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | H | E | P | L | A | L | N | S | F | L | P | M | L |
| Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |
|
|
|
|
|   |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
A | S | Q | A | Q | V | D | K | S | D | Y | D | M | V | D | Y | L | N | E | L | R | E | S | C | L | E | A | Y | T | G | I | V | Q | G | L | K | G | D | Q | E | N | V | H | P | D | V | M | L | V | Q | P | R | V | E | F | I | L | S | F | I |
| Template Known Secondary structure |   |
 |  | T |
|
|
|
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | S | S |
|
| G | G | G | G | G | T | G | G | G |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
742 | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . |
|   |
|   |   |
277 | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | E | I | A | E | Q | F | P | Y | L | T | G | Q | M | A | R | I | F | G | A | V | G | H | V | D | E | E | R | A | R | S | C | L | R | Y | L | V | S |
| Query Conservation |   |
|   |   |
|   |   |   |
|   |
|
|   |   |   |
|
|
|   |
|
|
|
|   |   |
|
|   |   |
|   |   |
|
|   |   |
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
D | H | I | A | G | D | E | D | H | T | D | G | V | V | A | C | A | A | G | L | I | G | D | L | C | T | A | F | G | K | D | V | L | K | L | V | E | A |
| Template Known Secondary structure |   |
 |  |  |  |  |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
802 | . | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . |
|   |