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Job DescriptionQ04736
Confidence100.00%DateWed Jul 10 14:37:29 BST 2013
Rank219Aligned Residues230
% Identity23%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   268.270.........280.........290...... ...300.........310.........320......
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Query Sequence  WEIPRESLRLEVKLGQGCFGEVWMGTWNG. TTKVAIKTLKPGTMMPEAFLQEAQIMKKLR
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Template Sequence  KQVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILK. . . . . . KEVIVANRVLQNSR
Template Known Secondary structure  T


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   112.......120.........130.........140.........150. ........160.....
 
   327..330......... 340.........350.........360.........370.........380.....
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Query Sequence  HDKLVPLYAVVSE. EPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYI
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Template Sequence  HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRE. . RVFSEDRARFYGAEIVSALDYL
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   207..210.........220.........230.........240.. .......250.........260....
 
   386.. .390.........400.........410.........420.........430.........440....
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Query Sequence  ERM. NYIHRDLRAANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALY
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Template Sequence  HSEKNVVYRDLKLENLMLDKDGHIKITDFGL. . . . . . . . . . . . . . . CKEPEYLAPEVLED
Template Known Secondary structure  TS







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   265....270.........280.........290..... ....300.........
 
   445....450.........460.........470.........480.........490.........500....
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Query Sequence  GRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMN
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Template Sequence  NDYGRAVDWWGLGVVMYEMMC. GRLPFYNQDHEKLFELILMEE. IRFPRTLGPEAKSLLS
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   324.....330.........340.... .....350.........360..... ....370.........380.
 
   505....510.... .....520..
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Query Sequence  LCWKKDPDER. . . . . PTFEYIQS
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Template Sequence  GLLKKDPKQRLGGGSEDAKEIMQ
Template Known Secondary structure  T
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   382.......390.........400....
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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