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Job DescriptionQ04736
Confidence100.00%DateWed Jul 10 14:37:29 BST 2013
Rank197Aligned Residues253
% Identity27%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   270.........280.........290.........300.........310.........320.........
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Query Sequence  IPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDK
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Template Sequence  TVARDITLLECVGKGRYGEVWRGSW. QGENVAVKIFSSRDEKSWFRETELYNTVMLRHEN
Template Known Secondary structure 
TTTTTT.TT
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   203......210.........220....... ..230.........240.........250.........260.
 
   330..... ....340.........350.........360.........370.........380....
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Query Sequence  LVPLYA. . . . . VVSEEPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAY
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Template Sequence  ILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTT. . . LDTVSCLRIVLSIASGLAH
Template Known Secondary structure  B

TT

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   262.......270.........280.........290......... 300.........310........
 
   385....390 .........400.........410.........420 .........430...
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Query Sequence  IERMNY. . . . . . . . IHRDLRAANILVGENLICKIADFGLARLIE. . . DNEYTARQGAKFP
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Template Sequence  LHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGT
Template Known Secondary structure  S
B
STT
B

S

SGGG
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   319320.........330.........340.........350.........360.........370........
 
   434.....440...... ...450.........460.........470......
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Query Sequence  IKWTAPEAALYGR. . . . . . FTIKSDVWSFGILQTELVTKGRVPYPGMVN. . . . . . . . . . .
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Template Sequence  KRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVPN
Template Known Secondary structure  GGG

TT


TT
T.TB
BTTB





TTTTTS
S
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   379380.........390.........400.........410...... ...420.........430.......
 
   477..480.........490.... .....500.........510.........520......
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Query Sequence  . . . . REVLEQVERGYRMPCPQG. . . . . . CPESLHELMNLCWKKDPDERPTFEYIQSFLED
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Template Sequence  DPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTK
Template Known Secondary structure  S

TTS






GGGGGS

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   438.440.........450.........460.........470.........480.........490.......
 
   527
Predicted Secondary structure 
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Query Sequence  Y
Query Conservation   
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Template Conservation 
Template Sequence  I
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   498
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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