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Job DescriptionQ04736
Confidence100.00%DateWed Jul 10 14:37:29 BST 2013
Rank231Aligned Residues258
% Identity33%Templatec2xbaA_
PDB info PDB header:transferaseChain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of human anaplastic lymphoma kinase in complex2 with pha-e429
Resolution1.95 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   268.270.........280...... ...290.........300..... ....310.........320.
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Query Sequence  WEIPRESLRLEVKLGQGCF. . . . GEVWMGTWNGTTKVAIKTL. . KPGTMMPEAFLQEAQI
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Template Sequence  FAGKTSSISDLKEVPRKNITLIRGLVYEGQVS. PLQVAVKTLPEVCSEQDELDFLMEALI
Template Known Secondary structure  TT
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   1098.1100.........1110.........1120......... 1130.........1140.........1150......
 
   322.......330......... 340.........350......... 360.........370.....
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Query Sequence  MKKLRHDKLVPLYAVVSE. EPIYIVTEFMSKGSLLDFLK. . . . . EGDGKYLKLPQLVDMA
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Template Sequence  ISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVA
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   1171........1180.........1190.........1200.........1210.........1220.........1230
 
   376...380.........390.........400.........410.........420.........430.....
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Query Sequence  AQIADGMAYIERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIK
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Template Sequence  RDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGM. . . . . . ARDIYAMLPVK
Template Known Secondary structure  TT


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   1231........1240.........1250.........1260.........1270... ......1280....
 
   436...440.........450.........460.........470.........480.........490.....
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Query Sequence  WTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGC
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Template Sequence  WMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNC
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   1295....1300.........1310.........1320.........1330.........1340.........1350....
 
   496...500.........510.........520.........530..
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Query Sequence  PESLHELMNLCWKKDPDERPTFEYIQSFLEDYFTATE
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Template Sequence  PGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPD
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   1355....1360.........1370.........1380.........1390.
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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