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Job DescriptionQ04736
Confidence100.00%DateWed Jul 10 14:37:29 BST 2013
Rank1Aligned Residues451
% Identity84%Templatec1y57A_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
Resolution1.91 Å
Model Dimensions (Å)X:78.585 Y:95.191 Z:48.769

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   91........100.........110.........120.........130.........140.........150
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Query Sequence  VTIFVALYDYEARTTEDLSFKKGERFQIINNTEGDWWEARSIATGKSGYIPSNYVVPADS
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Template Conservation      

          

    

   
       

       
  
 

 
 
     
Template Sequence  VTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDS
Template Known Secondary structure  TTSS
B


SSSB

B
TT

S

SSSSTTT

GGGTTS
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   83......90.........100.........110.........120.........130.........140..
 
   151........160.........170.........180.........190.........200.........210
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Query Sequence  IQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEVRGDNVKHY
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Template Conservation 
    

 
 
 
  

  
       
 



 
    
   


          
 
 
Template Sequence  IQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHY
Template Known Secondary structure  GGGSTTS

T
TT

TT

SSSTT
TTT
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   143......150.........160.........170.........180.........190.........200..
 
   211........220.........230.........240.........250.........260.........270
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Query Sequence  KIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHKLTTVCPTVKPQTQGLAKDAWEI
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Template Conservation   
     
         
 

  

  
      
   
                   

Template Sequence  KIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEI
Template Known Secondary structure 
SSS
SSTTSSS

TTSSS



B







SS



TTB
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   203......210.........220.........230.........240.........250.........260..
 
   271........280.........290.........300.........310.........320.........330
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Query Sequence  PRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKL
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Template Conservation        
   

 
 

 
  
       



 
         
  
  

  
 



Template Sequence  PRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKL
Template Known Secondary structure 
GGGTTTTT
TTSS



TTB
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   263......270.........280.........290.........300.........310.........320..
 
   331........340.........350.........360.........370.........380.........390
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Query Sequence  VPLYAVVSEEPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNY
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Template Conservation 
 
 
        

 

   


   
                  
    
  
     
Template Sequence  VQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNY
Template Known Secondary structure 


SSS


TTS

TT
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   323......330.........340.........350.........360.........370.........380..
 
   391........400.........410.........420.........430.........440.........450
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Query Sequence  IHRDLRAANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIK
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Template Conservation 

 

   
 
       

 




                     


       
 
Template Sequence  VHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIK
Template Known Secondary structure 
S

SGGG
GGG



TT


SS




TTTT
SGGGS




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   383......390.........400.........410.........420.........430.........440..
 
   451........460.........470.........480.........490.........500.........510
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Query Sequence  SDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKD
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Template Sequence  SDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKE
Template Known Secondary structure  TTS

SSTT

TT





TT

T
SS
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   443......450.........460.........470.........480.........490.........500..
 
   511........520.........530.........540.
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Query Sequence  PDERPTFEYIQSFLEDYFTATEPQYQPGENL
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Template Conservation 
  


   
   

         
      
Template Sequence  PEERPTFEYLQAFLEDYFTSTEPQYQPGENL
Template Known Secondary structure  GGGS

TT
TT



S

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   503......510.........520.........530...
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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