Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionA2A5Z6
DateWed Jul 10 14:17:52 BST 2013
Unique Job ID59c390432d72af01
SequenceMSNPGGRRNG ... Download FASTA

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:93.283 Y:58.389 Z:56.455
Model (left) based on template c3olmA_
Top template information
PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase rsp5;
PDBTitle: structure and function of a ubiquitin binding site within the2 catalytic domain of a hect ubiquitin ligase
Confidence and coverage
Confidence:100.0% Coverage: 55%
411 residues ( 55% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
599 residues ( 80%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSNPGGRRNGPVKLRLTVLCAKNLVKKDFFRLPDPFAKVVVDGSGQCHSTDTVKNTLDPK
Secondary structure 
SS confidence 
Disorder  ????????????
?
?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  WNQHYDLYIGKSDSVTISVWNHKKIHKKQGAGFLGCVRLLSNAINRLKDTGYQRLDLCKL
Secondary structure 
SS confidence 
Disorder 
?
???????
?????????????????
???
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  GPNDNDTVRGQIVVSLQSRDRIGTGGQVVDCSRLFDNDLPDGWEERRTASGRIQYLNHIT
Secondary structure 
SS confidence 
Disorder  ?????????
?????????????????????????
??
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  RTTQWERPTRPASEYSSPGRPLSCFVDENTPITGTNGATCGHSSDPRLAERRVRSQRHRN
Secondary structure 
SS confidence 
Disorder 
?????????????????????????????????????????????????????????
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  YMSRTHLHTPPDLPEGYEQRTTQQGQVYFLHTQTGVSTWHDPRVPRDLSNINCEELGPLP
Secondary structure 
SS confidence 
Disorder  ???????????
??
??????????????????????????
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  PGWEIRNTATGRVYFVDHNNRTTQFTDPRLSANLHLVLNRQNQLKDQQQQQVVPLCPDDT
Secondary structure 
SS confidence 
Disorder  ?
???
???
?
???????????
????????????????????
?
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  ECLTVPRYKRDLVQKLKILRQELSQQQPQAGHCRIEVSREEIFEESYRQVMKMRPKDLWK
Secondary structure 
SS confidence 
Disorder 
?????????
????????
???
?
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  RLMIKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHL
Secondary structure 
SS confidence 
Disorder 
?
???
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  SYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILEND
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  ITGVLDHTFCVEHNAYGEIIQHELKPNGKSIPVTEENKKEYVRLYVNWRFLRGIEAQFLA
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........610.........620.........630.........640.........650.........660
Sequence  LQKGFNEVIPQHLLKTFDEKELELIICGLGKIDVSDWKVNTRLKHCTPDSNVVKWFWKAV
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........670.........680.........690.........700.........710.........720
Sequence  EFFDEERRARLLQFVTGSSRVPLQGFKALQGAAGPRLFTIHQIDACTNNLPKAHTCFNRI
Secondary structure 
SS confidence 
Disorder 
??????????????
?
???
Disorder confidence 
 
   .........730.........740........
Sequence  DIPPYESYEKLYEKLLTAIEETCGFAVE
Secondary structure 
SS confidence 
Disorder 
??????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered ( 35%)
Alpha helix ( 28%)
Beta strand ( 18%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3olm chain A

3D model

Region: 295 - 742
Aligned: 411
Modelled: 421
Confidence: 100.0%
Identity: 53%
PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase rsp5;
PDBTitle: structure and function of a ubiquitin binding site within the2 catalytic domain of a hect ubiquitin ligase

Phyre2

PDB 1zvd chain A

3D model

Region: 369 - 741
Aligned: 373
Modelled: 373
Confidence: 100.0%
Identity: 97%
PDB header:ligase
Chain: A: PDB Molecule:smad ubiquitination regulatory factor 2;
PDBTitle: regulation of smurf2 ubiquitin ligase activity by anchoring the e2 to2 the hect domain

Phyre2

PDB 1nd7 chain A

3D model

Region: 371 - 743
Aligned: 371
Modelled: 373
Confidence: 100.0%
Identity: 51%
Fold: Hect, E3 ligase catalytic domain
Superfamily: Hect, E3 ligase catalytic domain
Family: Hect, E3 ligase catalytic domain

Phyre2

PDB 3g1n chain A

3D model

Region: 375 - 741
Aligned: 367
Modelled: 367
Confidence: 100.0%
Identity: 47%
PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase huwe1;
PDBTitle: catalytic domain of the human e3 ubiquitin-protein ligase2 huwe1

Phyre2

PDB 2oni chain A

3D model

Region: 369 - 740
Aligned: 369
Modelled: 372
Confidence: 100.0%
Identity: 54%
PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase nedd4-like protein;
PDBTitle: catalytic domain of the human nedd4-like e3 ligase

Phyre2

PDB 1c4z chain A

3D model

Region: 390 - 742
Aligned: 342
Modelled: 353
Confidence: 100.0%
Identity: 35%
Fold: Hect, E3 ligase catalytic domain
Superfamily: Hect, E3 ligase catalytic domain
Family: Hect, E3 ligase catalytic domain

Phyre2

PDB 2jqz chain A

3D model

Region: 10 - 140
Aligned: 131
Modelled: 131
Confidence: 99.9%
Identity: 100%
PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf2;
PDBTitle: solution structure of the c2 domain of human smurf2

Phyre2

PDB 3pt3 chain A

3D model

Region: 640 - 740
Aligned: 83
Modelled: 83
Confidence: 99.9%
Identity: 33%
PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase ubr5;
PDBTitle: crystal structure of the c-terminal lobe of the human ubr5 hect domain

Phyre2

PDB 2kxq chain A

3D model

Region: 248 - 333
Aligned: 86
Modelled: 86
Confidence: 99.9%
Identity: 98%
PDB header:protein binding
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf2;
PDBTitle: solution structure of smurf2 ww2 and ww3 bound to smad7 py motif2 containing peptide

Phyre2

PDB 2nq3 chain A domain 1

3D model

Region: 12 - 137
Aligned: 119
Modelled: 126
Confidence: 99.9%
Identity: 26%
Fold: C2 domain-like
Superfamily: C2 domain (Calcium/lipid-binding domain, CaLB)
Family: PLC-like (P variant)

Phyre2

PDB 2nq3 chain A

3D model

Region: 12 - 137
Aligned: 119
Modelled: 126
Confidence: 99.9%
Identity: 26%
PDB header:ligase
Chain: A: PDB Molecule:itchy homolog e3 ubiquitin protein ligase;
PDBTitle: crystal structure of the c2 domain of human itchy homolog2 e3 ubiquitin protein ligase

Phyre2

PDB 3nsj chain A

3D model

Region: 6 - 162
Aligned: 136
Modelled: 141
Confidence: 99.8%
Identity: 22%
PDB header:immune system
Chain: A: PDB Molecule:perforin-1;
PDBTitle: the x-ray crystal structure of lymphocyte perforin

Phyre2

PDB 1tk7 chain A

3D model

Region: 241 - 329
Aligned: 87
Modelled: 89
Confidence: 99.8%
Identity: 41%
PDB header:signaling protein
Chain: A: PDB Molecule:cg4244-pb;
PDBTitle: nmr structure of ww domains (ww3-4) from suppressor of2 deltex

Phyre2

PDB 1gmi chain A

3D model

Region: 11 - 138
Aligned: 119
Modelled: 128
Confidence: 99.8%
Identity: 21%
Fold: C2 domain-like
Superfamily: C2 domain (Calcium/lipid-binding domain, CaLB)
Family: PLC-like (P variant)

Phyre2

PDB 3m7f chain B

3D model

Region: 8 - 147
Aligned: 127
Modelled: 139
Confidence: 99.8%
Identity: 18%
PDB header:signaling protein/ligase
Chain: B: PDB Molecule:e3 ubiquitin-protein ligase nedd4;
PDBTitle: crystal structure of the nedd4 c2/grb10 sh2 complex

Phyre2

PDB 2dmh chain A

3D model

Region: 6 - 147
Aligned: 135
Modelled: 142
Confidence: 99.8%
Identity: 21%
PDB header:lipid binding protein
Chain: A: PDB Molecule:myoferlin;
PDBTitle: solution structure of the first c2 domain of human myoferlin

Phyre2

PDB 2fk9 chain A

3D model

Region: 2 - 137
Aligned: 123
Modelled: 136
Confidence: 99.8%
Identity: 21%
PDB header:transferase
Chain: A: PDB Molecule:protein kinase c, eta type;
PDBTitle: human protein kinase c, eta

Phyre2

PDB 1bdy chain A

3D model

Region: 14 - 141
Aligned: 112
Modelled: 128
Confidence: 99.8%
Identity: 16%
Fold: C2 domain-like
Superfamily: C2 domain (Calcium/lipid-binding domain, CaLB)
Family: PLC-like (P variant)

Phyre2

PDB 1rlw chain A

3D model

Region: 10 - 138
Aligned: 119
Modelled: 129
Confidence: 99.8%
Identity: 16%
Fold: C2 domain-like
Superfamily: C2 domain (Calcium/lipid-binding domain, CaLB)
Family: PLC-like (P variant)

Phyre2

PDB 3l9b chain A

3D model

Region: 12 - 144
Aligned: 119
Modelled: 133
Confidence: 99.8%
Identity: 17%
PDB header:membrane protein
Chain: A: PDB Molecule:otoferlin;
PDBTitle: crystal structure of rat otoferlin c2a

Phyre2
1
c3olmA_
2
c1zvdA_
3
d1nd7a_
4
c3g1nA_
5
c2oniA_
6
d1c4za_
7
c2jqzA_
8
c3pt3A_
9
c2kxqA_
10
d2nq3a1
11
c2nq3A_
12
c3nsjA_
13
c1tk7A_
14
d1gmia_
15
c3m7fB_
16
c2dmhA_
17
c2fk9A_
18
d1bdya_
19
d1rlwa_
20
c3l9bA_
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3olmA_
100.0 53 PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase rsp5;
PDBTitle: structure and function of a ubiquitin binding site within the2 catalytic domain of a hect ubiquitin ligase
2c1zvdA_
100.0 97 PDB header:ligase
Chain: A: PDB Molecule:smad ubiquitination regulatory factor 2;
PDBTitle: regulation of smurf2 ubiquitin ligase activity by anchoring the e2 to2 the hect domain
3d1nd7a_
100.0 51 Fold:Hect, E3 ligase catalytic domain
Superfamily:Hect, E3 ligase catalytic domain
Family:Hect, E3 ligase catalytic domain
4c3g1nA_
100.0 47 PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase huwe1;
PDBTitle: catalytic domain of the human e3 ubiquitin-protein ligase2 huwe1
5c2oniA_
100.0 54 PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase nedd4-like protein;
PDBTitle: catalytic domain of the human nedd4-like e3 ligase
6d1c4za_
100.0 35 Fold:Hect, E3 ligase catalytic domain
Superfamily:Hect, E3 ligase catalytic domain
Family:Hect, E3 ligase catalytic domain
7c2jqzA_
99.9 100 PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf2;
PDBTitle: solution structure of the c2 domain of human smurf2
8c3pt3A_
99.9 33 PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase ubr5;
PDBTitle: crystal structure of the c-terminal lobe of the human ubr5 hect domain
9c2kxqA_
99.9 98 PDB header:protein binding
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf2;
PDBTitle: solution structure of smurf2 ww2 and ww3 bound to smad7 py motif2 containing peptide
10d2nq3a1
99.9 26 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
11c2nq3A_
99.9 26 PDB header:ligase
Chain: A: PDB Molecule:itchy homolog e3 ubiquitin protein ligase;
PDBTitle: crystal structure of the c2 domain of human itchy homolog2 e3 ubiquitin protein ligase
12c3nsjA_
99.8 22 PDB header:immune system
Chain: A: PDB Molecule:perforin-1;
PDBTitle: the x-ray crystal structure of lymphocyte perforin
13c1tk7A_
99.8 41 PDB header:signaling protein
Chain: A: PDB Molecule:cg4244-pb;
PDBTitle: nmr structure of ww domains (ww3-4) from suppressor of2 deltex
14d1gmia_
99.8 21 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
15c3m7fB_
99.8 18 PDB header:signaling protein/ligase
Chain: B: PDB Molecule:e3 ubiquitin-protein ligase nedd4;
PDBTitle: crystal structure of the nedd4 c2/grb10 sh2 complex
16c2dmhA_
99.8 21 PDB header:lipid binding protein
Chain: A: PDB Molecule:myoferlin;
PDBTitle: solution structure of the first c2 domain of human myoferlin
17c2fk9A_
99.8 21 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c, eta type;
PDBTitle: human protein kinase c, eta
18d1bdya_
99.8 16 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
19d1rlwa_
99.8 16 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
20c3l9bA_
99.8 17 PDB header:membrane protein
Chain: A: PDB Molecule:otoferlin;
PDBTitle: crystal structure of rat otoferlin c2a
21d1qasa2
not modelled 99.8 23 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
22d2ep6a1
not modelled 99.8 23 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
23c2z0uB_
not modelled 99.8 11 PDB header:lipid binding protein
Chain: B: PDB Molecule:ww domain-containing protein 1;
PDBTitle: crystal structure of c2 domain of kibra protein
24c2nsqA_
not modelled 99.8 21 PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase nedd4-like protein;
PDBTitle: crystal structure of the c2 domain of the human e3 ubiquitin-protein2 ligase nedd4-like protein
25c1dqvA_
not modelled 99.8 21 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:synaptotagmin iii;
PDBTitle: crystal structure of synaptotagmin iii c2a/c2b
26d1wfja_
not modelled 99.7 15 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
27c3kwtA_
not modelled 99.7 26 PDB header:metal binding protein
Chain: A: PDB Molecule:munc13-1;
PDBTitle: munc13-1 c2b-domain, calcium-free
28c3jzyA_
not modelled 99.7 20 PDB header:endocytosis
Chain: A: PDB Molecule:intersectin 2;
PDBTitle: crystal structure of human intersectin 2 c2 domain
29d1dsya_
not modelled 99.7 28 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
30d1ugka_
not modelled 99.7 14 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
31c2q3xA_
not modelled 99.7 21 PDB header:transport protein
Chain: A: PDB Molecule:regulating synaptic membrane exocytosis protein 1;
PDBTitle: the rim1alpha c2b domain
32c2chdA_
not modelled 99.7 25 PDB header:protein transport
Chain: A: PDB Molecule:rabphilin-3a;
PDBTitle: crystal structure of the c2a domain of rabphilin-3a
33c2d8kA_
not modelled 99.7 21 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:synaptotagmin vii;
PDBTitle: solution structure of the first c2 domain of synaptotagmin2 vii
34c2enjA_
not modelled 99.7 16 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c theta type;
PDBTitle: solution sturcture of the c2 domain from human protein2 kinase c theta
35d2cjsa1
not modelled 99.7 21 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
36c2r83B_
not modelled 99.7 16 PDB header:endocytosis, exocytosis
Chain: B: PDB Molecule:synaptotagmin-1;
PDBTitle: crystal structure analysis of human synaptotagmin 1 c2a-c2b
37d2bwqa1
not modelled 99.7 26 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
38d2r83a1
not modelled 99.7 31 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
39d1wfma_
not modelled 99.7 17 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
40d2cjta1
not modelled 99.7 21 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
41d1rsya_
not modelled 99.7 18 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
42d1v27a_
not modelled 99.7 25 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
43c2enpA_
not modelled 99.7 18 PDB header:transport protein
Chain: A: PDB Molecule:b/k protein;
PDBTitle: solution structure of the first c2 domain from human b/k2 protein
44c1cjyB_
not modelled 99.7 18 PDB header:hydrolase
Chain: B: PDB Molecule:protein (cytosolic phospholipase a2);
PDBTitle: human cytosolic phospholipase a2
45d1a25a_
not modelled 99.7 27 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
46c3fbkB_
not modelled 99.6 23 PDB header:signaling protein
Chain: B: PDB Molecule:regulator of g-protein signaling 3;
PDBTitle: crystal structure of the c2 domain of the human regulator2 of g-protein signaling 3 isoform 6 (rgp3), northeast3 structural genomics consortium target hr5550a
47d2zkmx2
not modelled 99.6 20 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
48c3l4hA_
not modelled 99.6 26 PDB header:protein binding
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase hecw1;
PDBTitle: helical box domain and second ww domain of the human e3 ubiquitin-2 protein ligase hecw1
49c1djyB_
not modelled 99.6 22 PDB header:lipid degradation
Chain: B: PDB Molecule:phosphoinositide-specific phospholipase c,
PDBTitle: phosphoinositide-specific phospholipase c-delta1 from rat2 complexed with inositol-2,4,5-trisphosphate
50c2l5fA_
not modelled 99.6 18 PDB header:protein binding
Chain: A: PDB Molecule:pre-mrna-processing factor 40 homolog a;
PDBTitle: solution structure of the tandem ww domains from hypa/fbp11
51c1o6wA_
not modelled 99.6 33 PDB header:nuclear protein
Chain: A: PDB Molecule:pre-mrna processing protein prp40;
PDBTitle: solution structure of the prp40 ww domain pair of the yeast2 splicing factor prp40
52d2cm5a1
not modelled 99.6 27 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
53c2cm6A_
not modelled 99.6 25 PDB header:protein transport
Chain: A: PDB Molecule:rabphilin-3a;
PDBTitle: crystal structure of the c2b domain of rabphilin3a
54c2jxwA_
not modelled 99.6 15 PDB header:formin binding protein
Chain: A: PDB Molecule:ww domain-binding protein 4;
PDBTitle: solution structure of the tandem ww domains of fbp21
55c2dmgA_
not modelled 99.6 23 PDB header:lipid binding protein
Chain: A: PDB Molecule:kiaa1228 protein;
PDBTitle: solution structure of the third c2 domain of kiaa12282 protein
56c2b3rA_
not modelled 99.6 21 PDB header:transferase
Chain: A: PDB Molecule:phosphatidylinositol-4-phosphate 3-kinase c2 domain-
PDBTitle: crystal structure of the c2 domain of class ii phosphatidylinositide2 3-kinase c2
57d1rh8a_
not modelled 99.6 25 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
58d1dqva1
not modelled 99.6 19 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
59c2zajA_
not modelled 99.5 38 PDB header:protein binding
Chain: A: PDB Molecule:membrane-associated guanylate kinase, ww and pdz
PDBTitle: solution structure of the short-isoform of the second ww2 domain from the human membrane-associated guanylate kinase,3 ww and pdz domain-containing protein 1 (magi-1)
60d1byna_
not modelled 99.5 17 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
61c2l4jA_
not modelled 99.5 44 PDB header:transcription
Chain: A: PDB Molecule:yes-associated protein 2 (yap2);
PDBTitle: yap ww2
62d1dqva2
not modelled 99.5 24 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
63c2lb0A_
not modelled 99.5 39 PDB header:signaling protein/transcription
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf1;
PDBTitle: structure of the first ww domain of human smurf1 in complex with a di-2 phosphorylated human smad1 derived peptide
64c2lazA_
not modelled 99.5 39 PDB header:signaling protein/transcription
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf1;
PDBTitle: structure of the first ww domain of human smurf1 in complex with a2 mono-phosphorylated human smad1 derived peptide
65c2ysdA_
not modelled 99.5 41 PDB header:protein binding
Chain: A: PDB Molecule:membrane-associated guanylate kinase, ww and pdz
PDBTitle: solution structure of the first ww domain from the human2 membrane-associated guanylate kinase, ww and pdz domain-3 containing protein 1. magi-1
66d1tk7a1
not modelled 99.5 52 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain
67d1uowa_
not modelled 99.4 31 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
68c3ohmB_
not modelled 99.4 19 PDB header:signaling protein / hydrolase
Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase
PDBTitle: crystal structure of activated g alpha q bound to its effector2 phospholipase c beta 3
69c2djyA_
not modelled 99.4 88 PDB header:ligase/signaling protein
Chain: A: PDB Molecule:smad ubiquitination regulatory factor 2;
PDBTitle: solution structure of smurf2 ww3 domain-smad7 py peptide2 complex
70c3n5aA_
not modelled 99.4 23 PDB header:protein transport
Chain: A: PDB Molecule:synaptotagmin-7;
PDBTitle: synaptotagmin-7, c2b-domain, calcium bound
71d1i5hw_
not modelled 99.4 46 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain
72c3fdwA_
not modelled 99.4 20 PDB header:lipid binding protein
Chain: A: PDB Molecule:synaptotagmin-like protein 4;
PDBTitle: crystal structure of a c2 domain from human synaptotagmin-2 like protein 4
73c3qr0A_
not modelled 99.4 16 PDB header:hydrolase
Chain: A: PDB Molecule:phospholipase c-beta (plc-beta);
PDBTitle: crystal structure of s. officinalis plc21
74c2jmfA_
not modelled 99.4 58 PDB header:ligase/signaling protein
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase suppressor of deltex;
PDBTitle: solution structure of the su(dx) ww4- notch py peptide2 complex
75d2jmfa1
not modelled 99.4 73 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain
76c2lawA_
not modelled 99.4 53 PDB header:signaling protein/transcription
Chain: A: PDB Molecule:yorkie homolog;
PDBTitle: structure of the second ww domain from human yap in complex with a2 human smad1 derived peptide
77c1wmvA_
not modelled 99.4 39 PDB header:oxidoreductase, apoptosis
Chain: A: PDB Molecule:ww domain containing oxidoreductase;
PDBTitle: solution structure of the second ww domain of wwox
78c1e0mA_
not modelled 99.4 43 PDB header:de novo protein
Chain: A: PDB Molecule:wwprototype;
PDBTitle: prototype ww domain
79c2kq0A_
not modelled 99.4 53 PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase nedd4;
PDBTitle: human nedd4 3rd ww domain complex with ebola zaire virus matrix2 protein vp40 derived peptide ilptappeymea
80c2ysgA_
not modelled 99.4 38 PDB header:protein binding
Chain: A: PDB Molecule:syntaxin-binding protein 4;
PDBTitle: solution structure of the ww domain from the human syntaxin-2 binding protein 4
81d1tk7a2
not modelled 99.4 59 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain
82c2kykA_
not modelled 99.3 54 PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase itchy homolog;
PDBTitle: the sandwich region between two lmp2a py motif regulates the2 interaction between aip4ww2domain and py motif
83c1ymzA_
not modelled 99.3 39 PDB header:unknown function
Chain: A: PDB Molecule:cc45;
PDBTitle: cc45, an artificial ww domain designed using statistical2 coupling analysis
84c2ez5W_
not modelled 99.3 36 PDB header:signalling protein,ligase
Chain: W: PDB Molecule:e3 ubiquitin-protein ligase nedd4;
PDBTitle: solution structure of the dnedd4 ww3* domain- comm lpsy2 peptide complex
85c1wr7A_
not modelled 99.3 49 PDB header:ligase
Chain: A: PDB Molecule:nedd4-2;
PDBTitle: solution structure of the third ww domain of nedd4-2
86c2ysfA_
not modelled 99.3 50 PDB header:protein binding
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase itchy homolog;
PDBTitle: solution structure of the fourth ww domain from the human2 e3 ubiquitin-protein ligase itchy homolog, itch
87c2dmvA_
not modelled 99.3 38 PDB header:ligase
Chain: A: PDB Molecule:itchy homolog e3 ubiquitin protein ligase;
PDBTitle: solution structure of the second ww domain of itchy homolog2 e3 ubiquitin protein ligase (itch)
88c1yiuA_
not modelled 99.3 66 PDB header:ligase
Chain: A: PDB Molecule:itchy e3 ubiquitin protein ligase;
PDBTitle: itch e3 ubiquitin ligase ww3 domain
89c2yshA_
not modelled 99.3 30 PDB header:protein binding
Chain: A: PDB Molecule:growth-arrest-specific protein 7;
PDBTitle: solution structure of the ww domain from the human growth-2 arrest-specific protein 7, gas-7
90d1w15a_
not modelled 99.3 24 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:Synaptotagmin-like (S variant)
91c2ysbA_
not modelled 99.3 43 PDB header:protein binding
Chain: A: PDB Molecule:salvador homolog 1 protein;
PDBTitle: solution structure of the first ww domain from the mouse2 salvador homolog 1 protein (sav1)
92c2fjuB_
not modelled 99.3 22 PDB header:signaling protein,apoptosis/hydrolase
Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: activated rac1 bound to its effector phospholipase c beta 2
93c2dwvB_
not modelled 99.3 29 PDB header:protein binding
Chain: B: PDB Molecule:salvador homolog 1 protein;
PDBTitle: solution structure of the second ww domain from mouse2 salvador homolog 1 protein (mww45)
94c1wr4A_
not modelled 99.3 56 PDB header:ligase
Chain: A: PDB Molecule:ubiquitin-protein ligase nedd4-2;
PDBTitle: solution structure of the second ww domain of nedd4-2
95d1k9ra_
not modelled 99.3 43 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain
96c2yscA_
not modelled 99.3 28 PDB header:protein binding
Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding family
PDBTitle: solution structure of the ww domain from the human amyloid2 beta a4 precursor protein-binding family b member 3, apbb3
97d2f21a1
not modelled 99.2 50 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain
98d1nmva1
not modelled 99.1 33 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain
99d1f8ab1
not modelled 99.0 38 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain
100d1i8gb_
not modelled 99.0 40 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain
101d2itka1
not modelled 99.0 43 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain
102c2ysiA_
not modelled 99.0 21 PDB header:protein binding
Chain: A: PDB Molecule:transcription elongation regulator 1;
PDBTitle: solution structure of the first ww domain from the mouse2 transcription elongation regulator 1, transcription factor3 ca150
103d1pina1
not modelled 99.0 45 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain
104c1yw5A_
not modelled 98.2 24 PDB header:isomerase
Chain: A: PDB Molecule:peptidyl prolyl cis/trans isomerase;
PDBTitle: peptidyl-prolyl isomerase ess1 from candida albicans
105d1o6wa2
not modelled 98.2 39 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain
106d1o6wa1
not modelled 98.1 21 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain
107c2enqA_
not modelled 98.0 15 PDB header:transferase
Chain: A: PDB Molecule:phosphatidylinositol-4,5-bisphosphate 3-kinase
PDBTitle: solution structure of the c2 domain from human pi3-kinase2 p110 subunit alpha
108c2dk7A_
not modelled 98.0 28 PDB header:transcription
Chain: A: PDB Molecule:transcription elongation regulator 1;
PDBTitle: solution structure of ww domain in transcription elongation2 regulator 1
109d2rm0w1
not modelled 97.9 22 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain
110d2e45a1
not modelled 97.7 27 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain
111c3pfqA_
not modelled 97.7 27 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii
112d1zr7a1
not modelled 97.6 19 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain
113d1ywia1
not modelled 97.6 19 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain
114c1zr7A_
not modelled 97.5 19 PDB header:signaling protein
Chain: A: PDB Molecule:huntingtin-interacting protein hypa/fbp11;
PDBTitle: solution structure of the first ww domain of fbp11
115c2dk1A_
not modelled 97.5 24 PDB header:gene regulation
Chain: A: PDB Molecule:ww domain-binding protein 4;
PDBTitle: solution structure of ww domain in ww domain binding2 protein 4 (wbp-4)
116c1ywjA_
not modelled 97.5 19 PDB header:structural protein
Chain: A: PDB Molecule:formin-binding protein 3;
PDBTitle: structure of the fbp11ww1 domain
117d1e7ua2
not modelled 97.4 17 Fold:C2 domain-like
Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB)
Family:PLC-like (P variant)
118c1eg4A_
not modelled 97.4 21 PDB header:structural protein
Chain: A: PDB Molecule:dystrophin;
PDBTitle: structure of a dystrophin ww domain fragment in complex2 with a beta-dystroglycan peptide
119d2dk1a1
not modelled 97.4 24 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain
120d2ho2a1
not modelled 97.3 34 Fold:WW domain-like
Superfamily:WW domain
Family:WW domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite