|   |
20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | |
. | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | D | G | E | L | Y | S | Q | Y | K | V | V | R | T | L | G | H | G | T | Y | A | K | V | L | L | A | K | H | W | L | T | G | T | P | V | A | V | K | V | L | L | . |
K | N | K | P | C | F | Q | P | A | M | K | E | A | N | I | M | K | K |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |
|   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |
|
|   |   |
|
|
|
|   |
|   | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |
|   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
Template Sequence |   |
D | Q | G | D | P | R | L | L | L | D | S | Y | V | K | I | G | E | G | S | T | G | I | V | C | L | A | R | E | K | H | S | G | R | Q | V | A | V | K | M | M | D | L | R | K | Q | Q | R | R | E | L | L | F | N | E | V | V | I | M | R | D |
Template Known Secondary structure |   |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  | T | T | T |
|
| S |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
399 | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . |
  |
  |   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | K | H | P | N | I | V | S | L | L | Q | V | F | E | T | K | T | R | G | Y | L | I | M | E | L | V | E | G | Q | E | L | Y | E | Y | I | K | S | S | G | H | I | E | E | D | E | A | R | Q | I | F | L | Q | I | L | S | A | V | S | Y | C |
Query Conservation |   |
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|
|   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|
Template Sequence |   |
Y | Q | H | F | N | V | V | E | M | Y | K | S | Y | L | V | G | E | E | L | W | V | L | M | E | F | L | Q | G | G | A | L | T | D | I | V | S | Q | V | R | . |
L | N | E | E | Q | I | A | T | V | C | E | A | V | L | Q | A | L | A | Y | L |
Template Known Secondary structure |   |
|
|
| T | T | B |
|
|  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |
|
|
|
| S |
| B |  |  |  |  |  | T | T |
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
459 | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | |
. | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . |
  |
  |   |
139 | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | G | L | G | I | V | H | R | D | L | K | P | D | N | I | M | I | D | D | K | G | S | I | K | I | I | D | F | G | L | S | T | Q | V | K | P | G | D | L | L | D | E | H | C | G | A | Y | A | F | G | A | P | E | L | F | L | W | K | S | Y |
Query Conservation |   |
|   |   |   |
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |   |   |
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|
|   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |
Template Sequence |   |
H | A | Q | G | V | I | H | R | D | I | K | S | D | S | I | L | L | T | L | D | G | R | V | K | L | S | D | F | G | F | C | A | Q | I | S | K | D | V | P | K | R | K | L | V | G | T | P | Y | W | M | A | P | E | V | I | S | R | S | L | Y |
Template Known Secondary structure |   |
 |  | T | T |  |  |
|
|
|
| S | G | G | G |  |  |  |
| T | T |
|
|  |  |  |
|
|
| T | T |
|  |  |
|
| S | S | S |
|
| B |
|
|
| S |
| G | G | G |
|
|  |  |  |  | T | T |
|
| B |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
518 | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . |
  |
  |   |
199 | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | |
|
|
. | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | G | T | K | S | D | L | W | A | L | G | V | I | L | Y | Y | M | V | V | G | K | V | P | F | D | S | Y | I | I | P | E | L | Q | R | Q | I | L | A | G | . |
. |
. |
V | Y | P | A | P | C | G | V | S | N | E | L | K | D | L | L | S | L |
Query Conservation |   |
  |   |   |
|   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |   |   |   |
|
|
|
|
|
|
|   |
|
|
|
|
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |
Template Sequence |   |
. |
A | T | E | V | D | I | W | S | L | G | I | M | V | I | E | M | V | D | G | E | P | P | Y | F | S | D | S | P | V | Q | A | M | K | R | L | R | D | S | P | P | P | K | L | K | N | S | H | K | V | S | P | V | L | R | D | F | L | E | R |
Template Known Secondary structure |   |
. |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
| T | T | T | T | S |
|  |  |  |  |  |  |  |  |  |  | S | S |
|
|
|
| T | T | G | G | G | S |
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
579 | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . |
  |
  |   |
256 | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | M | T | V | N | P | K | Y | R | P | T | V | T | E | V | M | K | H | P | W | L | R | G |
Query Conservation |   |
  |
|   |   |
|
|   |   |
|   |
|   |   |
|
|
|   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |
|   |   |   |   |   |
Template Sequence |   |
M | L | V | R | D | P | Q | E | R | A | T | A | Q | E | L | L | D | H | P | F | L | L | Q |
Template Known Secondary structure |   |
 | S |
| S | S | T | T | T | S |
|
|  |  |  |  |  | T | S | G | G | G | G | G |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
638 | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 |
  |