Return to main results Retrieve Phyre Job Id

Job DescriptionA0AUV4
Confidence100.00%DateTue Jul 30 13:10:30 BST 2013
Rank234Aligned Residues246
% Identity23%Templatec3zbfA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase ros; PDBTitle: structure of human ros1 kinase domain in complex with crizotinib
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   26...30.........40.........50 .........60 .........70.........80
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Query Sequence  SQYKVVRTLGHGTYAKVLLAKHWLT. . . GTPVAVKVLL. . KNKPCFQPAMKEANIMKKIK
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Template Sequence  EKLTLRLLLGSGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFN
Template Known Secondary structure  GG


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   1943......1950.........1960.........1970.........1980.........1990.........2000..
 
   81........90.........100.........110........ .120.........130...
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Query Sequence  HPNIVSLLQVFETKTRGYLIMELVEGQELYEYIKSSGH. . . . . . . IEEDEARQIFLQILS
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Template Sequence  HPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISK
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   2006...2010.........2020.........2030.........2040.........2050.........2060.....
 
   134.....140.........150.........160.........170.........180.........190...
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Query Sequence  AVSYCHGLGIVHRDLKPDNIMIDDKGSIKIIDFGLSTQVKPGDLLDEHCGAYAFGAPELF
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Template Sequence  GCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIG. . . . DFGLARDIYLPVRWMAPESL
Template Known Secondary structure  TT
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   2066...2070.........2080.........2090.........2100. ........2110.........2120.
 
   194.....200.........210....... ..220.........230....... ..240.........250.
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Query Sequence  LWKSYDGTKSDLWALGVILYYMVV. GKVPFDSYIIPELQRQILAG. VYPAPCGVSNELKD
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Template Sequence  MDGIF. TTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWN
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   2134.... .2140.........2150.........2160.........2170.........2180.........2190..
 
   252.......260.........270......
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Query Sequence  LLSLLMTVNPKYRPTVTEVMKHPWL
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Template Sequence  LMTQCWAQEPDQRPTFHRIQDQLQL
Template Known Secondary structure  T
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   2193......2200.........2210.......
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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