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Job DescriptionA0AUV4
Confidence100.00%DateTue Jul 30 13:10:30 BST 2013
Rank205Aligned Residues240
% Identity23%Templatec1xkkA_
PDB info PDB header:transferaseChain: A: PDB Molecule:epidermal growth factor receptor; PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   26...30.........40.........50.........60.........70.........80.....
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Query Sequence  SQYKVVRTLGHGTYAKVLLAKHWLTGTPVAVKVLLKNKPCFQPAMKEANIMKKIKHPNIV
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Template Sequence  TEFKKIKVLGSGAFGTVYKGLWIPVKIPVAIKELREKAN. . KEILDEAYVMASVDNPHVC
Template Known Secondary structure  TT
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   710.........720.........730.........740........ .750.........760.......
 
   86...90.........100.........110.........120.........130.........140.....
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Query Sequence  SLLQVFETKTRGYLIMELVEGQELYEYIKSSGHIEEDEARQIFLQILSAVSYCHGLGIVH
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Template Sequence  RLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVH
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SSS

TT
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TT


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   776...780.........790.........800.........810.........820.........830.....
 
   146...150.........160.........170.........180.........190.........200.....
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Query Sequence  RDLKPDNIMIDDKGSIKIIDFGLSTQVKPGDLLDEHCGAYAFGAPELFLWKSYDGTKSDL
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Template Sequence  RDLAARNVLVKTPQHVKITDFGLAKLLGAEE. . . . . KVPIKWMALESILHRIY. THQSDV
Template Known Secondary structure  S


GGGTT


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   836...840.........850.........860...... ...870.........880... ......
 
   206...210....... ..220.........230....... ..240.........250.........260...
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Query Sequence  WALGVILYYMVV. GKVPFDSYIIPELQRQILAG. VYPAPCGVSNELKDLLSLLMTVNPKY
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Template Sequence  WSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADS
Template Known Secondary structure  TTS

TTTTS
GGGT





TTB
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   898.900.........910.........920.........930.........940.........950.......
 
   264.....270...
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Query Sequence  RPTVTEVMKH
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Template Sequence  RPKFRELIIE
Template Known Secondary structure  S

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   958.960.......
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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