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Job DescriptionA0AUV4
Confidence100.00%DateTue Jul 30 13:10:30 BST 2013
Rank19Aligned Residues270
% Identity25%Templatec1oplA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
Resolution3.42 Å
Model Dimensions (Å)X:60.675 Y:50.745 Z:46.587

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20.........30.........40.........50.........60.
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Query Sequence  PAHIEEELPPPSPQPSNPEDGELYSQYKVVRTLGHGTYAKVLLAKHWLTGTPVAVKVLLK
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Template Sequence  PAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKE
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B

GGGSGGGTTSSGGGT

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   235....240.........250.........260.........270.........280.........290....
 
   62.......70.........80.........90.........100.........110........ .
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Query Sequence  NKPCFQPAMKEANIMKKIKHPNIVSLLQVFETKTRGYLIMELVEGQELYEYIKSSGH. . I
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Template Sequence  DTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEV
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   295....300.........310.........320.........330.........340.........350....
 
   120.........130.........140.........150.........160.........170.........
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Query Sequence  EEDEARQIFLQILSAVSYCHGLGIVHRDLKPDNIMIDDKGSIKIIDFGLSTQVKPGDLLD
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Template Sequence  NAVVLLYMATQISSAMEYLEKKNFIHRNLAARNCLVGENHLVKVADFGLSRLMTGDTYTA
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SGGG
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   355....360.........370.........380.........390.........400.........410....
 
   180... ......190.........200.........210....... ..220.........230......
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Query Sequence  EHCG. . AYAFGAPELFLWKSYDGTKSDLWALGVILYYMVV. GKVPFDSYIIPELQRQILA
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Template Sequence  HAGAKFPIKWTAPESLAYNKF. SIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEK
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   415....420.........430..... ....440.........450.........460.........470...
 
   237 ..240.........250.........260.........270..
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Query Sequence  G. VYPAPCGVSNELKDLLSLLMTVNPKYRPTVTEVMK
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Template Sequence  DYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQ
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   474.....480.........490.........500.........510
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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