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Job DescriptionA0AUV4
Confidence100.00%DateTue Jul 30 13:10:30 BST 2013
Rank245Aligned Residues225
% Identity24%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   25....30.........40.........50.........60.........70.........80....
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Query Sequence  YSQYKVVRTLGHGTYAKVLLAKHWLTGTPVAVKVLLKNKPCFQPAMKEANIMKKIKHPNI
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Template Sequence  PKDLTFLKELGTGQFGVVKYGKWR. GQYDVAIKMIKE. . . . . . . FIEEAKVMMNLSHEKL
Template Known Secondary structure  GGGSTTSS
T.TT


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   399400.........410.........420.. .......430.... .....440.........450
 
   85....90.........100.........110... ......120.........130.........140...
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Query Sequence  VSLLQVFETKTRGYLIMELVEGQELYEYI. KSSGHIEEDEARQIFLQILSAVSYCHGLGI
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Template Sequence  VQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQF
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   458.460.........470.........480.........490.........500.........510.......
 
   144.....150.........160.........170.........180.........190.........200...
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Query Sequence  VHRDLKPDNIMIDDKGSIKIIDFGLSTQVKPGDLLDEHCGAYAFGAPELFLWKSYDGTKS
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Template Sequence  LHRDLAARNCLVNDQGVVKVSDFGFP. . . . . . . . . . . . . . . VRWSPPEVLMYSKF. SSKS
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SGGG
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   518.520.........530.........540... ......550....... ..560.
 
   204.....210....... ..220.........230....... ..240.........250.........260.
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Query Sequence  DLWALGVILYYMVV. GKVPFDSYIIPELQRQILAG. VYPAPCGVSNELKDLLSLLMTVNP
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Template Sequence  DIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKA
Template Known Secondary structure  TTS

TTTTS
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TTS
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   579580.........590.........600.........610.........620.........630........
 
   262.......270...
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Query Sequence  KYRPTVTEVMKH
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Template Sequence  DERPTFKILLSN
Template Known Secondary structure  GGS

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   639640.........650
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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