|   |   |
360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | R | S | L | L | T | L | E | D | N | E | L | G | S | G | N | F | G | T | V | K | K | G | Y | Y | Q | M | K | K | V | V | K | T | V | A | V | K | I | L | K | N | E | A | N | D | P | A | L | K | D | E | L | L | A | E | A | N | V | M | Q |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   | . | . |
|
|
|
|   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |
|
|   |
|
|   |
| Template Sequence |   |
D | P | K | K | K | Y | T | R | F | E | K | I | G | Q | G | A | S | G | T | V | Y | T | A | M | D | V | A | T | G | Q | E | . |
. |
V | A | I | R | Q | M | N | L | Q | Q | Q | P | K | . |
. |
K | E | L | I | I | N | E | I | L | V | M | R |
| Template Known Secondary structure |   |
| T | T | T | T | B |
| S |
|  |  |
|
|
| S | S | S |
|  |  |  |  |  |  | B | T | T | T |
|
|  | . | . |  |  |  |  |  |  |  | G | G | G |
| S |
| . | . |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  | . | . |  |  |  |  |  |  |  |
|
|
|  |  |  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
265 | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | |
|
. | . | . | . | 300 | . | . | . | . | . | . | . | . | |
|
. | 310 | . | . | . | . | . | . | . | . | . | 320 |
|   |
|   |   |
420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | |
. | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  |  | . |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Q | L | D | N | P | Y | I | V | R | M | I | G | I | C | . |
E | A | E | S | W | M | L | V | M | E | M | A | E | L | G | P | L | N | K | Y | L | Q | Q | N | R | H | I | K | D | K | N | I | I | E | L | V | H | Q | V | S | M | G | M | K | Y |
| Query Conservation |   |
  |
|   |
|   |   |
|
|   |   |   |
|   |   | . |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
| Template Sequence |   |
E | N | K | N | P | N | I | V | N | Y | L | D | S | Y | L | V | G | D | E | L | W | V | V | M | E | Y | L | A | G | G | S | L | T | D | V | V | T | E | T | C | . |
M | D | E | G | Q | I | A | A | V | C | R | E | C | L | Q | A | L | E | F |
| Template Known Secondary structure |   |
 |
|
|
| T | T | B |
|
|  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |
|
| T | T |
| B |  |  |  |  |  |  |  | S |
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
321 | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | |
. | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
479 | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | E | E | S | N | F | V | H | R | D | L | A | A | R | N | V | L | L | V | T | Q | H | Y | A | K | I | S | D | F | G | L | S | K | A | L | R | A | D | E | N | Y | Y | K | A | Q | T | H | G | K | W | P | V | K | W | Y | A | P | E | C | I |
| Query Conservation |   |
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |
|   |   |
|
|   |   |
| Template Sequence |   |
L | H | S | N | Q | V | I | H | R | D | I | K | S | D | N | I | L | L | G | M | D | G | S | V | K | L | T | D | F | G | F | C | A | Q | I | T | P | E | Q | S | K | R | S | T | M | V | G | . |
. |
. |
T | P | Y | W | M | A | P | E | V | V |
| Template Known Secondary structure |   |
 |  |  | T | T |  |  |
|
|
|
| S | G | G | G |  |  |  |
| T | T |
|
|  |  |  |
|
|
| T | T |
|  |  |
|
| S | T | T |
|
| B |
|
|
|
| S | . | . | . |
| G | G | G |
|
|  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | |
|
|
. | . | . | 430 | . | . | . | . | . | . |
|   |
|   |   |
539 | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | |
|
. | . | . | . | . | . | 590 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
N | Y | Y | K | F | S | S | K | S | D | V | W | S | F | G | V | L | M | W | E | A | F | S | Y | G | Q | K | P | Y | R | G | M | K | G | S | E | V | T | A | M | L | E | K | G | E | . |
. |
R | M | G | C | P | A | G | C | P | R | E | M | Y |
| Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . | . |   |   |   |   |
|   |   |   |
|   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |
| . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
| Template Sequence |   |
T | R | K | A | Y | G | P | K | V | D | I | W | S | L | G | I | M | A | I | E | M | I | E | . |
G | E | P | P | Y | L | N | E | N | P | L | R | A | L | Y | L | I | A | T | N | G | T | P | E | L | Q | N | P | E | K | L | S | A | I | F | R |
| Template Known Secondary structure |   |
S | S | S |
| B |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| T | T | T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |
| S |
|
|
| S | S | G | G | G | S |
|  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
437 | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | |
460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . |
|   |
|   |   |
597 | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | L | M | N | L | C | W | T | Y | D | V | E | N | R | P | G | F | T | A | V | E | L | R | L | R | N | Y | Y | Y | D | V | V | N |
| Query Conservation |   |
  |
|   |   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |
|
| . | . | . |
|   |
|
|   |   |   |   |   |   |
| Template Sequence |   |
D | F | L | N | R | C | L | D | M | D | V | E | K | R | G | S | A | K | E | L | . |
. |
. |
L | Q | H | Q | F | L | K | I | A | K |
| Template Known Secondary structure |   |
 |  |  |  |  |  | T |
| S | S | T | T | T | S |
|
|  |  |  |  | . | . | . | T | T |
| G | G | G | G | G |
|
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  | . | . | . |  |
|
|  |  |  |
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
496 | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | |
|
|
. | . | . | . | 520 | . | . | . | . | . |
|   |