Job Description P48025 Confidence 100.00% Date Wed Jul 10 14:17:05 BST 2013 Rank 87 Aligned Residues 266 % Identity 38% Template c4e1zA_ PDB info PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structure of mouse tyk-2 complexed to a 3-aminoindazole inhibitor Resolution 2.50 Å

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		347	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.			.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.
Predicted Secondary structure																																									.	.
Query SS confidence																																									.	.
Query Sequence		A	D	P	E	E	I	R	P	K	E	V	Y	L	D	R	S	L	L	T	L	E	D	N	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	.	.	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D
Query Conservation																																									.	.
Alig confidence															.	.	.	.	.	.	.	.																			.	.																	.
Template Conservation															.	.	.	.	.	.	.	.																																					.
Template Sequence		S	D	P	T	V	F	H	K	R	Y	L	K	K	.	.	.	.	.	.	.	.	I	R	D	L	G	E	G	H	F	G	K	V	S	L	Y	C	Y	D	P	T	N	D	G	T	G	E	M	V	A	V	K	A	L	K	E	G	.	C	G
Template Known Secondary structure				T	T	B			G	G	G				.	.	.	.	.	.	.	.								S	S										T	T			S	S											T	T	.
Template Predicted Secondary structure															.	.	.	.	.	.	.	.																																					.
Template SS confidence
		883	.	.	.	.	.	.	890	.	.	.	.	.									.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.		.	.
		405	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I	C	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q	N	R	H	I	K	D	K	N
Query Conservation
Alig confidence																																																				.
Template Conservation																																																				.
Template Sequence		P	Q	L	R	S	G	W	Q	R	E	I	E	I	L	R	T	L	Y	H	E	H	I	V	K	Y	K	G	C	C	E	D	K	S	V	Q	L	V	M	E	Y	V	P	L	G	S	L	R	D	Y	L	.	P	R	H	C	V	G	L	A	Q
Template Known Secondary structure																					T	T	B																				T	T							G	.	G	G	S
Template Predicted Secondary structure																																																				.
Template SS confidence
		934	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.		.	.	.	.	.	.	990	.	.
		465	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	L	L	F	A	Q	Q	I	C	E	G	M	A	Y	L	H	A	Q	H	Y	I	H	R	A	L	A	A	R	N	V	L	L	D	N	D	R	L	V	K	I	G	D	F	G	L	A	K	A	V	P	E	G	H	E	Y	Y	R	V	R	E
Template Known Secondary structure																			T	T				S			S	G	G	G					G	G	G								T	T						T	T		S
Template Predicted Secondary structure
Template SS confidence
		996	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.
		525	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		H	G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																							.								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																							.
Template Sequence		D	G	D	S	P	V	F	W	Y	A	P	E	C	L	K	E	C	K	F	Y	Y	A	S	D	V	W	S	F	G	V	T	L	Y	E	L	L	T	.	Y	C	D	S	N	Q	S	P	H	T	K	F	T	E	L	I	G	H	T	Q	G	Q
Template Known Secondary structure			S	S	S		G	G	G								S																					T	.	T	T		T	T	S	S											S
Template Predicted Secondary structure																																							.
Template SS confidence
		1056	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.		.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.
		570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	K	G	S	E	V	T	A	M	L	E	K	G	E	R	M	G	C	P	A	G	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	T	A	V	E	L	R	L	R	N	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	T	V	L	R	L	T	E	L	L	E	R	G	E	R	L	P	R	P	D	R	C	P	C	E	I	Y	H	L	M	K	N	C	W	E	T	E	A	S	F	R	P	T	F	Q	N	L	V	P	I	L	Q	T	A
Template Known Secondary structure														T							T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1115	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D