Job Description P48025 Confidence 100.00% Date Wed Jul 10 14:17:05 BST 2013 Rank 254 Aligned Residues 252 % Identity 24% Template c3zonA_ PDB info PDB header:transferase Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: human tyk2 pseudokinase domain bound to a kinase inhibitor Resolution 2.15 Å

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		358	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	L	D	R	S	L	L	T	L	E	D	N	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V
Query Conservation
Alig confidence											.																			.	.	.														.	.
Template Conservation											.																			.	.	.														.	.
Template Sequence		R	V	D	Q	K	E	I	T	Q	.	L	S	H	L	G	Q	G	T	R	T	N	V	Y	E	G	R	L	R	.	.	.	V	E	L	R	V	V	L	K	V	L	D	P	S	.	.	H	H	D	I	A	L	A	F	Y	E	T	A	S	L
Template Known Secondary structure					G	G	G				.								T	T										.	.	.												S		.	.
Template Predicted Secondary structure											.																			.	.	.														.	.
Template SS confidence
		583	.	.	.	.	.	.	590	.		.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.				610	.	.	.	.	.	.	.	.	.	620	.	.			.	.	.	.	.	.	.	630	.	.	.	.	.	.
		418	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.		.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.		.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.
Predicted Secondary structure																		.																						.
Query SS confidence																		.																						.
Query Sequence		M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I	C	.	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	.	Q	Q	N	R	H	I	K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G
Query Conservation																		.																						.
Alig confidence																		.																						.
Template Conservation
Template Sequence		M	S	Q	V	S	H	T	H	L	A	F	V	H	G	V	C	V	R	G	P	E	N	I	M	V	T	E	Y	V	E	H	G	P	L	D	V	W	L	R	R	E	R	G	H	V	P	M	A	W	K	M	V	V	A	Q	Q	L	A	S	A
Template Known Secondary structure			T	T				T	T	B										T	T										T	T		B								T	T	T
Template Predicted Secondary structure
Template SS confidence
		662	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.
		476	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y	A	P
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	S	Y	L	E	N	K	N	L	V	H	G	N	V	C	G	R	N	I	L	L	A	R	L	G	L	A	E	G	T	S	P	F	I	K	L	S	D	P	G	V	G	L	G	A	L	S	R	E	E	R	V	E	R	I	P	W	L	A	P
Template Known Secondary structure								T	T							S	G	G	G									S	T	T												S		G	G	G	S								T	T	T	T	S		G
Template Predicted Secondary structure
Template SS confidence
		722	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.
		536	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	G	S	E	V	T	A	M	L	E	K	G	E	R	M	G	C	P	A	G	C	P	R	E	M
Query Conservation
Alig confidence					.	.	.																																																	.	.	.	.	.
Template Conservation					.	.	.																																																	.	.	.	.	.
Template Sequence		E	C	L	.	.	.	P	L	S	T	A	M	D	K	W	G	F	G	A	T	L	L	E	I	C	F	D	G	E	A	P	L	Q	S	R	S	P	S	E	K	E	H	F	Y	Q	R	Q	H	R	L	P	E	P	Q	.	.	.	.	.	L
Template Known Secondary structure		G	G		.	.	.				T	T															T	T	T			T	T	T	T	S											T	T								.	.	.	.	.
Template Predicted Secondary structure					.	.	.																																																	.	.	.	.	.
Template SS confidence
		782	.	.				.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.						.
		596	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	T	A	V	E	L	R	L	R	N	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	T	L	T	S	Q	C	L	T	Y	E	P	T	Q	R	P	S	F	R	T	I	L	R	D	L	T	R	L
Template Known Secondary structure									T		S	S	G	G	G	S												T	T
Template Predicted Secondary structure
Template SS confidence
		842	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D