Job Description P48025 Confidence 100.00% Date Wed Jul 10 14:17:05 BST 2013 Rank 159 Aligned Residues 260 % Identity 31% Template c3zbfA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase ros; PDBTitle: structure of human ros1 kinase domain in complex with crizotinib Resolution 2.20 Å

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		355	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.		390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.
Predicted Secondary structure																																					.
Query SS confidence																																					.
Query Sequence		K	E	V	Y	L	D	R	S	L	L	T	L	E	D	N	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K	K	V	.	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A
Query Conservation																																					.
Alig confidence																																					.														.
Template Conservation																																																			.
Template Sequence		E	N	L	P	A	F	P	R	E	K	L	T	L	R	L	L	L	G	S	G	E	V	Y	E	G	T	A	V	D	I	L	G	V	G	S	G	E	I	K	V	A	V	K	T	L	K	K	G	S	.	T	D	Q	E	K	I	E	F	L	K
Template Known Secondary structure						B			G	G	G																			T	S	S		S	S													S	S		.
Template Predicted Secondary structure																																																			.
Template SS confidence
		1935	.	.	.	.	1940	.	.	.	.	.	.	.	.	.	1950	.	.	.	.	.	.	.	.	.	1960	.	.	.	.	.	.	.	.	.	1970	.	.	.	.	.	.	.	.	.	1980	.	.	.		.	.	.	.	.	.	1990	.	.	.
		414	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.		.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.								.	460	.	.	.	.	.
Predicted Secondary structure																						.																										.	.	.	.	.	.	.
Query SS confidence																						.																										.	.	.	.	.	.	.
Query Sequence		E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I	C	.	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q	N	R	.	.	.	.	.	.	.	H	I	K	D	K	N	I
Query Conservation																						.																										.	.	.	.	.	.	.
Alig confidence																						.																										.	.	.	.	.	.	.
Template Conservation
Template Sequence		E	A	H	L	M	S	K	F	N	H	P	N	I	L	K	Q	L	G	V	C	L	L	N	E	P	Q	Y	I	I	L	E	L	M	E	G	G	D	L	L	T	Y	L	R	K	A	R	M	A	T	F	Y	G	P	L	L	T	L	V	D	L
Template Known Secondary structure								T				T	T	B									S	S	S	S									T	T		B											S		T	T			S	S
Template Predicted Secondary structure
Template SS confidence
		1997	.	.	2000	.	.	.	.	.	.	.	.	.	2010	.	.	.	.	.	.	.	.	.	2020	.	.	.	.	.	.	.	.	.	2030	.	.	.	.	.	.	.	.	.	2040	.	.	.	.	.	.	.	.	.	2050	.	.	.	.	.	.
		466	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H
Query Conservation
Alig confidence																																																.	.	.	.	.	.	.	.
Template Conservation																																																.	.	.	.	.	.	.	.
Template Sequence		V	D	L	C	V	D	I	S	K	G	C	V	Y	L	E	R	M	H	F	I	H	R	D	L	A	A	R	N	C	L	V	S	V	K	D	Y	T	S	P	R	I	V	K	I	G	D	.	.	.	.	.	.	.	.	F	G	L	A	R	D
Template Known Secondary structure																		T	T				S				G	G	G				S		S	S	S	S	S									.	.	.	.	.	.	.	.		T	T
Template Predicted Secondary structure																																																.	.	.	.	.	.	.	.
Template SS confidence
		2057	.	.	2060	.	.	.	.	.	.	.	.	.	2070	.	.	.	.	.	.	.	.	.	2080	.	.	.	.	.	.	.	.	.	2090	.	.	.	.	.	.	.	.	.	2100	.	.									.	.	.	.	.	.
		526	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	G	S	E	V	T	A	M	L	E	K	G	E	R	M
Query Conservation
Alig confidence
Template Conservation
Template Sequence		I	Y	L	P	V	R	W	M	A	P	E	S	L	M	D	G	I	F	T	T	Q	S	D	V	W	S	F	G	I	L	I	W	E	I	L	T	L	G	H	Q	P	Y	P	A	H	S	N	L	D	V	L	N	Y	V	Q	T	G	G	R	L
Template Known Secondary structure						G	G	G	S																												T	T	S			S	S	T	T												T	T
Template Predicted Secondary structure
Template SS confidence
		2109	2110	.	.	.	.	.	.	.	.	.	2120	.	.	.	.	.	.	.	.	.	2130	.	.	.	.	.	.	.	.	.	2140	.	.	.	.	.	.	.	.	.	2150	.	.	.	.	.	.	.	.	.	2160	.	.	.	.	.	.	.	.
		586	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	C	P	A	G	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	T	A	V	E	L	R	L	R	N	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	P	P	R	N	C	P	D	D	L	W	N	L	M	T	Q	C	W	A	Q	E	P	D	Q	R	P	T	F	H	R	I	Q	D	Q	L	Q	L	F
Template Known Secondary structure					T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		2181	.	.	.	.	.	.	.	.	2190	.	.	.	.	.	.	.	.	.	2200	.	.	.	.	.	.	.	.	.	2210	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D