Job Description P48025 Confidence 100.00% Date Wed Jul 10 14:17:05 BST 2013 Rank 91 Aligned Residues 230 % Identity 27% Template c3vw6B_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor Resolution 2.40 Å

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		369	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R
Query Conservation
Alig confidence																								.	.										.	.	.	.	.	.	.	.
Template Conservation																								.	.										.	.	.	.	.	.	.	.
Template Sequence		V	V	L	G	K	G	T	Y	G	I	V	Y	A	G	R	D	L	S	N	Q	V	R	.	.	I	A	I	K	E	I	P	E	Q	.	.	.	.	.	.	.	.	P	L	H	E	E	I	A	L	H	K	H	L	K	H	K	N	I	V	Q
Template Known Secondary structure								S	S	S								T	T	T				.	.										.	.	.	.	.	.	.	.										T	T				T	T	B
Template Predicted Secondary structure																								.	.										.	.	.	.	.	.	.	.
Template SS confidence
		684	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.			.	.	.	.	710	.	.	.	.									.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.
		429	430	.	.	.		.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.				.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.
Predicted Secondary structure							.																										.	.	.
Query SS confidence							.																										.	.	.
Query Sequence		M	I	G	I	C	.	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q	N	R	.	.	.	H	I	K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F
Query Conservation							.																										.	.	.
Alig confidence							.																										.	.	.
Template Conservation
Template Sequence		Y	L	G	S	F	S	E	N	G	F	I	K	I	F	M	E	Q	V	P	G	G	S	L	S	A	L	L	R	S	K	W	G	P	L	K	D	N	E	Q	T	I	G	F	Y	T	K	Q	I	L	E	G	L	K	Y	L	H	D	N	Q	I
Template Known Secondary structure									T	T										T	T		B								T	T				T	T																						T	T
Template Predicted Secondary structure
Template SS confidence
		740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.
		485	.	.	.	.	490	.	.	.	.	.	.		.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.
Predicted Secondary structure														.																																															.
Query SS confidence														.																																															.
Query Sequence		V	H	R	D	L	A	A	R	N	V	L	L	.	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K	.
Query Conservation														.																																															.
Alig confidence														.																		.	.	.	.	.	.	.	.	.	.	.	.	.																	.
Template Conservation																																.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		V	H	R	D	I	K	G	D	N	V	L	I	N	T	Y	S	G	V	L	K	I	S	D	F	G	T	S	K	R	L	.	.	.	.	.	.	.	.	.	.	.	.	.	T	G	T	L	Q	Y	M	A	P	E	I	I	D	K	G	P	R
Template Known Secondary structure				S			S	G	G	G					T	T	T									S	S					.	.	.	.	.	.	.	.	.	.	.	.	.				G	G	G										G	G
Template Predicted Secondary structure																																.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.														830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.
			543	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.			.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.
Predicted Secondary structure		.																														.	.
Query SS confidence		.																														.	.
Query Sequence		.	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	.	.	G	S	E	V	T	A	M	L	E	K	G	E	R	M	G	C	P	A	G	C	P	R	E	M	Y	D	L	M
Query Conservation		.																														.	.
Alig confidence		.																				.										.	.
Template Conservation																						.
Template Sequence		G	Y	G	K	A	A	D	I	W	S	L	G	C	T	I	I	E	M	A	T	.	G	K	P	P	F	Y	E	L	G	E	P	Q	A	A	M	F	K	V	G	M	F	K	V	H	P	E	I	P	E	S	M	S	A	E	A	K	A	F	I
Template Known Secondary structure		G		S																		.	S	S		T	T	G	G	G		S												T							T	T	S
Template Predicted Secondary structure																						.
Template SS confidence
		857	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.		.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.
		600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	L	C	W	T	Y	D	V	E	N	R	P	G	F	T	A	V	E	L	R	L	R	N	Y	Y	Y
Query Conservation
Alig confidence																			.	.	.
Template Conservation																			.	.	.
Template Sequence		L	K	C	F	E	P	D	P	D	K	R	A	C	A	N	D	L	.	.	.	L	V	D	E	F	L
Template Known Secondary structure					T		S		T	T	T	S							.	.	.		T	S	G	G	G
Template Predicted Secondary structure																			.	.	.
Template SS confidence
		916	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.				.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D