Job Description P48025 Confidence 100.00% Date Wed Jul 10 14:17:05 BST 2013 Rank 85 Aligned Residues 236 % Identity 25% Template c3p23B_ PDB info PDB header:hydrolase, transferase Chain: B: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1; PDBTitle: crystal structure of the human kinase and rnase domains in complex2 with adp Resolution 2.70 Å

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		365	.	.	.	.	370	.	.	.	.	.	.	.	.		.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.		.
Predicted Secondary structure																.																																												.
Query SS confidence																.																																												.
Query Sequence		T	L	E	D	N	E	L	G	S	G	N	F	G	T	.	V	K	K	G	Y	Y	Q	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	.	D
Query Conservation																.																																												.
Alig confidence																.							.	.	.	.															.	.	.	.	.															.
Template Conservation																							.	.	.	.															.	.	.	.	.
Template Sequence		F	C	P	K	D	V	L	G	H	G	A	E	G	T	I	V	Y	R	G	M	F	.	.	.	.	D	N	R	D	V	A	V	K	R	I	L	P	E	C	.	.	.	.	.	F	S	F	A	D	R	E	V	Q	L	L	R	E	S	D	E
Template Known Secondary structure												S	T	T								S	.	.	.	.	S	S	S									T	T	T	.	.	.	.	.													T	S
Template Predicted Secondary structure																							.	.	.	.															.	.	.	.	.
Template SS confidence
		571	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.					.	.	.	.	.	.	.	.	600	.	.	.	.	.						.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.
		423	.	.	.	.	.	.	430	.	.	.	.	.	.		.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.		.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Predicted Secondary structure																.																							.
Query SS confidence																.																							.
Query Sequence		N	P	Y	I	V	R	M	I	G	I	C	E	A	E	.	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q	N	R	.	H	I	K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E
Query Conservation																.																							.
Alig confidence																.											.												.
Template Conservation																											.
Template Sequence		H	P	N	V	I	R	Y	F	C	T	E	K	D	R	Q	F	Q	Y	I	A	I	E	L	C	A	.	A	T	L	Q	E	Y	V	E	Q	K	D	F	A	H	L	G	L	E	P	I	T	L	L	Q	Q	T	T	S	G	L	A	H	L	H
Template Known Secondary structure			T	T	B										S	S										S	.									S	S	S		S			S	S
Template Predicted Secondary structure																											.
Template SS confidence
		622	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.		.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680
		481	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.						.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.
Predicted Secondary structure																							.	.	.	.	.
Query SS confidence																							.	.	.	.	.
Query Sequence		E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	.	.	.	.	.	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y	A	P
Query Conservation																							.	.	.	.	.
Alig confidence																							.	.	.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																													.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		S	L	N	I	V	H	R	D	L	K	P	H	N	I	L	I	S	M	P	N	A	H	G	K	I	K	A	M	I	S	D	F	G	L	C	K	K	L	A	P	G	T	E	.	.	.	.	.	.	.	.	.	.	.	.	G	W	I	A	P
Template Known Secondary structure			T	T							S	G	G	G							B	T	T	T	B									S										T	.	.	.	.	.	.	.	.	.	.	.	.	T	S			G
Template Predicted Secondary structure																																													.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		681	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.													.	.	.	.	.
		536	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.			.	.	.	.	.	.	590	.	.	.
Predicted Secondary structure																																																		.	.
Query SS confidence																																																		.	.
Query Sequence		E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	G	S	E	V	T	A	M	L	E	K	G	E	.	.	R	M	G	C	P	A	G	C	P	R
Query Conservation																																																		.	.
Alig confidence																																																		.	.
Template Conservation
Template Sequence		E	M	L	S	E	E	N	P	T	Y	T	V	D	I	F	S	A	G	C	V	F	Y	Y	V	I	S	E	G	S	H	P	F	G	K	S	L	Q	R	Q	A	N	I	L	L	G	A	C	S	L	D	C	L	H	P	E	K	H	E	D	V
Template Known Secondary structure		G	G	G	T						T																	T	S			S	S												T	T					T	T	S		T	T
Template Predicted Secondary structure
Template SS confidence
		741	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800
		594	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	T	A	V	E	L	R	L	R	N	Y	Y	Y
Query Conservation
Alig confidence																									.	.	.
Template Conservation																									.	.	.
Template Sequence		I	A	R	E	L	I	E	K	M	I	A	M	D	P	Q	K	R	P	S	A	K	H	V	.	.	.	L	K	H	P	F	F
Template Known Secondary structure											T		S	S	G	G	G								.	.	.		T	S	G	G	G
Template Predicted Secondary structure																									.	.	.
Template SS confidence
		804	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.				.	.	.	830	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D