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Job DescriptionP48025
Confidence100.00%DateWed Jul 10 14:17:05 BST 2013
Rank213Aligned Residues232
% Identity25%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   365....370.........380.........390.........400.........410.........420....
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Query Sequence  TLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNP
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Template Sequence  FEYLKLLGKGTFGKVILVKEKATGRY. . YAMKILK. . . . . . . . . KEVIVANRVLQNSRHP
Template Known Secondary structure  TTTTT

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   150.........160.........170..... ....180.. .......190........
 
   425....430....... ..440.........450.........460.........470.........480..
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Query Sequence  YIVRMIGICEAES. WMLVMEMAELGPLNKYLQQNRHIKDKNIIELVHQVSMGMKYLEES.
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Template Sequence  FLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEK
Template Known Secondary structure  TB


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   209210.........220.........230.........240.........250.........260........
 
   483......490.........500.........510.........520.........530.........540..
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Query Sequence  NFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYK
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Template Sequence  NVVYRDLKLENLMLDKDGHIKITDFGLCK. . . . . . . . . . . . . . . . . EPEYLAPEVLEDND
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   269270.........280.........290....... ..300.........310.
 
   543......550.........560.........570.........580.........590.........600..
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Query Sequence  FSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLC
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Template Sequence  YGRAVDWWGLGVVMYEMMC. GRLPFYNQDHEKLFELILMEE. IRFPRTLGPEAKSLLSGL
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   326...330.........340.... .....350.........360..... ....370.........380...
 
   603......610 .........620.........
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Query Sequence  WTYDVENR. . . . . PGFTAVELRLRNYYYDVVN
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Template Sequence  LKKDPKQRLGGGSEDAKEI. . . MQHRFFAGIV
Template Known Secondary structure  T
SSTTTSTT
STTT...TSGGGTT

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   384.....390.........400.. .......410..
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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