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Job DescriptionP48025
Confidence100.00%DateWed Jul 10 14:17:05 BST 2013
Rank224Aligned Residues250
% Identity21%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   365....370.........380.........390.........400.........410.........420....
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Query Sequence  TLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNP
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Template Sequence  ITLLECVGKGRYGEVWRGSW. . . . QGENVAVKIFSSRD. . . EKSWFRETELYNTVMLRHE
Template Known Secondary structure  TT....TT
GGG...S



T
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   208.210.........220....... ..230.........240. ........250.........260
 
   425....430... ......440.........450.........460.........470.........
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Query Sequence  YIVRMIGIC. . . . . EAESWMLVMEMAELGPLNKYLQQNRHIKDKNIIELVHQVSMGMKYL
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Template Sequence  NILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYL. QLTTLDTVSCLRIVLSIASGLAHL
Template Known Secondary structure  TB

TT

TT
B.

B
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   261........270.........280.........290..... ....300.........310.........
 
   480.... .....490.........500.........510.........520........ .530
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Query Sequence  EESNF. . . . . . . . VHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKW. PV
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Template Sequence  HIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTK
Template Known Secondary structure  S
B
STT
B

S

SGGG
TTS



TT
TTTT








G
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   320.........330.........340.........350.........360.........370.........
 
   531........540.. .......550.........560.........570..
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Query Sequence  KWYAPECINYYK. . . . . . FSSKSDVWSFGVLMWEAFSYGQKPYRGMKG. . . . . . . . . . . .
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Template Sequence  RYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVPND
Template Known Secondary structure  GG

TT


TT
T.TB
BTTB





TTTTTS
SS
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   380.........390.........400.........410...... ...420.........430........
 
   573......580.........590 .........600.........610.........620...
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Query Sequence  . . . SEVTAMLEKGERMGCPAG. . . . . . CPREMYDLMNLCWTYDVENRPGFTAVELRLRNY
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Template Sequence  PSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI
Template Known Secondary structure 

TTS






GGGGGS

SSGGGS


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   439440.........450.........460.........470.........480.........490........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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