Job Description P48025 Confidence 100.00% Date Wed Jul 10 14:17:05 BST 2013 Rank 220 Aligned Residues 244 % Identity 24% Template c3kvwA_ PDB info PDB header:transferase Chain: A: PDB Molecule:dual specificity tyrosine-phosphorylation-regulated kinase PDBTitle: crystal structure of dual-specificity tyrosine phosphorylation2 regulated kinase 2 (dyrk2) in complex with an indirubin ligand Resolution 2.28 Å

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		365	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.
Predicted Secondary structure																																																													.
Query SS confidence																																																													.
Query Sequence		T	L	E	D	N	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	.
Query Conservation																																																													.
Alig confidence																										.	.										.	.	.																						.
Template Conservation																										.	.										.	.	.
Template Sequence		Y	E	V	L	K	V	I	G	K	G	S	F	G	Q	V	V	K	A	Y	D	H	K	V	H	.	.	Q	H	V	A	L	K	M	V	R	.	.	.	N	E	K	R	F	H	R	Q	A	A	E	E	I	R	I	L	E	H	L	R	K	Q
Template Known Secondary structure											S	S	S									T	T	T	T	.	.										.	.	.	S																				T	T
Template Predicted Secondary structure																										.	.										.	.	.
Template SS confidence
		149	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.			.	.	.	.	.	.	.	180	.				.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.
							424	.	.	.	.	.	430	.	.	.		.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.			.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.											.																									.	.
Query SS confidence		.	.	.	.	.											.																									.	.
Query Sequence		.	.	.	.	.	P	Y	I	V	R	M	I	G	I	C	.	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q	N	.	.	R	H	I	K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G
Query Conservation		.	.	.	.	.											.																									.	.
Alig confidence		.	.	.	.	.											.													.												.	.
Template Conservation																														.
Template Sequence		D	K	D	N	T	M	N	V	I	H	M	L	E	N	F	T	F	R	N	H	I	C	M	T	F	E	L	L	.	S	M	N	L	Y	E	L	I	K	K	N	K	F	Q	G	F	S	L	P	L	V	R	K	F	A	H	S	I	L	Q	C
Template Known Secondary structure			T	T	S		S		B										T	T										.			B								T	T	T
Template Predicted Secondary structure																														.
Template SS confidence
		204	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.		.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.
		476	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500			.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.
Predicted Secondary structure																											.	.
Query SS confidence																											.	.
Query Sequence		M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	.	.	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y
Query Conservation																											.	.
Alig confidence																											.	.																						.	.	.	.	.	.	.
Template Conservation																																																		.	.	.	.	.	.	.
Template Sequence		L	D	A	L	H	K	N	R	I	I	H	C	D	L	K	P	E	N	I	L	L	K	Q	Q	G	R	S	G	I	K	V	I	D	F	G	S	S	C	Y	E	H	Q	R	V	Y	T	I	Q	.	.	.	.	.	.	.	S	R	F	Y	R
Template Known Secondary structure									T				S			S	G	G	G				S	S	T	T	S									T	T				T	T								.	.	.	.	.	.	.		G	G	G
Template Predicted Secondary structure																																																		.	.	.	.	.	.	.
Template SS confidence
		263	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310								.	.	.	.	.
		534	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.
Predicted Secondary structure																																																							.	.	.	.	.	.	.
Query SS confidence																																																							.	.	.	.	.	.	.
Query Sequence		A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	G	S	E	V	T	A	M	L	E	K	G	E	R	M	G	.	.	.	.	.	.	.
Query Conservation																																																							.	.	.	.	.	.	.
Alig confidence																														.																									.	.	.	.	.	.	.
Template Conservation																														.
Template Sequence		A	P	E	V	I	L	G	A	R	Y	G	M	P	I	D	M	W	S	L	G	C	I	L	A	E	L	L	T	.	G	Y	P	L	L	P	G	E	D	E	G	D	Q	L	A	C	M	I	E	L	L	G	M	P	S	Q	K	L	L	D	A
Template Known Secondary structure								T	B				T																	.	S	S		S	S			S	S																						T
Template Predicted Secondary structure																														.
Template SS confidence
		317	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.		.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.
																																																		587	.	.	590	.	.	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	C	P	A	G	C	P	R	E	M	Y	D	L
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		S	K	R	A	K	N	F	V	S	K	G	Y	P	R	Y	C	T	V	T	T	L	S	D	V	V	L	N	G	G	R	S	R	R	G	K	L	R	G	P	P	E	S	R	E	W	G	N	A	L	K	G	C	D	D	P	L	F	L	D	F
Template Known Secondary structure		B	T	T					B					B	T	T	S																T	T						S	T	T		S						T	T	T
Template Predicted Secondary structure
Template SS confidence
		376	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.
		599	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	T	A	V	E	L	R	L	R	N	Y	Y	Y
Query Conservation
Alig confidence																				.	.	.
Template Conservation																				.	.	.
Template Sequence		L	K	Q	C	L	E	W	D	P	A	V	R	M	T	P	G	Q	A	.	.	.	L	R	H	P	W	L
Template Known Secondary structure						T		S	S	T	T	T	S							.	.	.		T	S	T	T	T
Template Predicted Secondary structure																				.	.	.
Template SS confidence
		439	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.				.	.	.	460	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D