Job Description P48025 Confidence 100.00% Date Wed Jul 10 14:17:05 BST 2013 Rank 176 Aligned Residues 237 % Identity 38% Template c3k54A_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases. Resolution 1.94 Å

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		354	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	K	E	V	Y	L	D	R	S	L	L	T	L	E	D	N	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A
Query Conservation
Alig confidence															.																		.	.	.													.	.	.	.	.	.	.	.	.	.
Template Conservation															.																		.	.	.													.	.	.	.	.	.	.	.	.	.
Template Sequence		Y	G	S	W	E	I	D	P	K	D	L	T	F	.	L	K	E	L	G	T	G	Q	F	G	V	V	K	Y	G	K	W	.	.	.	R	G	Q	Y	D	V	A	I	K	M	I	K	.	.	.	.	.	.	.	.	.	.	E	F	I	E
Template Known Secondary structure			G	G	G	B			G	G	G				.						S	T	T	S	S								.	.	.	T	T	T										.	.	.	.	.	.	.	.	.	.			T	T
Template Predicted Secondary structure															.																		.	.	.													.	.	.	.	.	.	.	.	.	.
Template SS confidence
		392	.	.	.	.	.	.	.	400	.	.	.	.		.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.				.	.	.	.	.	.	.	.	430	.	.	.											.	.	.	.
		414	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.		.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.		.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.
Predicted Secondary structure																									.																			.
Query SS confidence																									.																			.
Query Sequence		E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I	C	E	A	E	.	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	.	Q	Q	N	R	H	I	K	D	K	N	I	I	E	L	V	H	Q
Query Conservation																									.																			.
Alig confidence																									.																			.
Template Conservation
Template Sequence		E	A	K	V	M	M	N	L	S	H	E	K	L	V	Q	L	Y	G	V	C	T	K	Q	R	P	I	F	I	I	T	E	Y	M	A	N	G	C	L	L	N	Y	L	R	E	M	R	H	R	F	Q	T	Q	Q	L	L	E	M	C	K	D
Template Known Secondary structure												T	T	B									S	S	S	S									T	T										G	G	G
Template Predicted Secondary structure
Template SS confidence
		445	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.
		472	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K
Query Conservation
Alig confidence																																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		V	C	E	A	M	E	Y	L	E	S	K	Q	F	L	H	R	D	L	A	A	R	N	C	L	V	N	D	Q	G	V	V	K	V	S	D	F	G	F	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	V	R
Template Known Secondary structure												T	T				S			S	G	G	G					T	T												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	G
Template Predicted Secondary structure																																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		505	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.																				.	.
		532	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.
Predicted Secondary structure
Query SS confidence
Query Sequence		W	Y	A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	G	S	E	V	T	A	M	L	E	K	G	E	R	M	G	C	P	A	G	C
Query Conservation
Alig confidence
Template Conservation
Template Sequence		W	S	P	P	E	V	L	M	Y	S	K	F	S	S	K	S	D	I	W	A	F	G	V	L	M	W	E	I	Y	S	L	G	K	M	P	Y	E	R	F	T	N	S	E	T	A	E	H	I	A	Q	G	L	R	L	Y	R	P	H	L	A
Template Known Secondary structure		G																													T	T	S			T	T	T	T	S											T	T							T	T	S
Template Predicted Secondary structure
Template SS confidence
		563	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.
		592	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	T	A	V	E	L	R	L	R	N	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	E	K	V	Y	T	I	M	Y	S	C	W	H	E	K	A	D	E	R	P	T	F	K	I	L	L	S	N	I	L	D	V
Template Known Secondary structure												T	T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		623	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D