Job Description P48025 Confidence 100.00% Date Wed Jul 10 14:17:05 BST 2013 Rank 102 Aligned Residues 266 % Identity 34% Template c3fupB_ PDB info PDB header:transferase Chain: B: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes Resolution 2.40 Å

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		355	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.			.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.
Predicted Secondary structure																																	.	.
Query SS confidence																																	.	.
Query Sequence		K	E	V	Y	L	D	R	S	L	L	T	L	E	D	N	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	.	.	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L
Query Conservation																																	.	.
Alig confidence														.																			.	.																	.	.
Template Conservation														.																																					.	.
Template Sequence		D	P	T	Q	F	E	E	R	H	L	K	F	.	L	Q	Q	L	G	K	G	N	F	G	S	V	E	M	C	R	Y	D	P	L	Q	D	N	T	G	E	V	V	A	V	K	K	L	Q	H	S	.	.	T	E	E	H	L	R	D	F	E
Template Known Secondary structure			T	T				G	G	G				.								S	S										T	T	S	S	S											S			.	.
Template Predicted Secondary structure														.																																					.	.
Template SS confidence
		840	.	.	.	.	.	.	.	.	.	850	.		.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.			.	.	890	.	.	.	.	.	.
		413	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.		.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.
Predicted Secondary structure																																												.
Query SS confidence																																												.
Query Sequence		A	E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I	C	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	.	Q	Q	N	R	H	I	K	D	K	N	I	I	E	L	V	H	Q
Query Conservation																																												.
Alig confidence																											.																	.
Template Conservation																											.
Template Sequence		R	E	I	E	I	L	K	S	L	Q	H	D	N	I	V	K	Y	K	G	V	C	Y	S	N	L	.	K	L	I	M	E	Y	L	P	Y	G	S	L	R	D	Y	L	Q	K	H	K	E	R	I	D	H	I	K	L	L	Q	Y	T	S	Q
Template Known Secondary structure									T				T	T	B												.								T	T		B					T	T	T	S	T	T	T
Template Predicted Secondary structure																											.
Template SS confidence
		897	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.		.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.
		472	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K
Query Conservation
Alig confidence																																																										.	.
Template Conservation																																																										.	.
Template Sequence		I	C	K	G	M	E	Y	L	G	T	K	R	Y	I	H	R	D	L	A	T	R	N	I	L	V	E	N	E	N	R	V	K	I	G	D	F	G	L	T	K	V	L	P	Q	D	K	E	K	V	K	E	P	G	E	S	P	.	.	I	F
Template Known Secondary structure											T	T	T								G	G	G						T	T								T	T						T	T							S	S				.	.	G	G
Template Predicted Secondary structure																																																										.	.
Template SS confidence
		960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.			.	.
		532	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.																	570	.	.	.	.	.
Predicted Secondary structure																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		W	Y	A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	M	K	G	S	E	V
Query Conservation																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																.								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																.
Template Sequence		W	Y	A	P	E	S	L	T	E	S	K	F	S	V	A	S	D	V	W	S	F	G	V	V	L	Y	E	L	F	T	.	Y	I	E	K	S	K	S	P	P	A	E	F	M	R	M	I	G	N	D	K	Q	G	Q	M	I	V	F	H	L
Template Known Secondary structure		G																														.	T	T		G	G	G	S											S				S	S
Template Predicted Secondary structure																																.
Template SS confidence
		1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.		1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.
		576	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	A	M	L	E	K	G	E	R	M	G	C	P	A	G	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	T	A	V	E	L	R	L	R	N	Y	Y	Y	D	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		I	E	L	L	K	N	N	G	R	L	P	R	P	D	G	C	P	D	E	I	Y	M	I	M	T	E	C	W	N	N	N	V	N	Q	R	P	S	F	R	D	L	A	L	R	V	D	Q	I	R	D	Q	M
Template Known Secondary structure							T	T							T	T			T	T									T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1079	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D