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Job DescriptionP48025
Confidence100.00%DateWed Jul 10 14:17:05 BST 2013
Rank230Aligned Residues242
% Identity25%Templatec3fmeA_
PDB info PDB header:transferaseChain: A: PDB Molecule:dual specificity mitogen-activated protein kinase kinase 6; PDBTitle: crystal structure of human mitogen-activated protein kinase kinase 62 (mek6) activated mutant (s207d, t211d)
Resolution2.26 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   357..360.........370.........380.........390.........400.........410......
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Query Sequence  VYLDRSLLTLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEAN
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Template Sequence  MEVKADDLEP. IMELGRGAYGVVEKMRHVPSG. . QIMAVKRIRNS. . . QEQKRLLMDLDI
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   46...50..... ....60.........70...... ...80....... ..90.........
 
   417..420.........430...... ...440.........450.... .....460.........470..
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Query Sequence  VMQQLDNPYIVRMIGICEAE. SWMLVMEMAELGPLNKYL. . . QQNRHIKDKNIIELVHQV
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Template Sequence  SMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSI
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   103......110.........120.........130.........140.........150.........160..
 
   473......480 .........490.........500.........510.........520.........530.
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Query Sequence  SMGMKYLE. ESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVK
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Template Sequence  VKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFAGCK. . . . . . . . . . . . . . . . . . . P
Template Known Secondary structure  S






SGGG

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   163......170.........180.........190.........200.. .
 
   532....... 540.........550.........560.........570. ........580.......
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Query Sequence  WYAPECIN. . YYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMK. . GSEVTAMLEKGERMGC
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Template Sequence  YMAPERINPELNQYSVKSDIWSLGITMIELAI. LRFPYDSWGTPFQQLKQVVEEPSPQLP
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   219220.........230.........240.........250 .........260.........270.......
 
   588.590.........600.........610.........620.......
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Query Sequence  PAGCPREMYDLMNLCWTYDVENRPGFTAVELRLRNYYYDV
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Template Sequence  ADKFSAEFVDFTSQCLKKNSKERPTYPEL. . . MQHPFFTL
Template Known Secondary structure  TTTS
T
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   280.........290.........300........ .310......
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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