|   |   |
368 | . | 370 | . | . | . | |
. | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |
| Query SS confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | N | E | L | G | S | . |
G | N | F | G | T | V | K | K | G | Y | Y | Q | M | K | K | V | V | K | T | V | A | V | K | I | L | K | N | E | A | N | D | P | A | L | K | D | E | L | L | A | E | A | N | V | M | Q | Q | L | D | N | P | Y | I |
| Query Conservation |   |
  |   |   |
|
|   | . |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|   |   |
|
| Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |
|
|   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |
|   |   | . | . |
|
|
|
|   |
|   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |
|
|
|
|
| Template Sequence |   |
G | A | H | I | G | N | Y | Q | I | V | K | K | V | K | L | A | Y | H | T | T | T | G | Q | K | . |
. |
V | A | L | K | I | I | N | K | K | V | M | . |
. |
. |
. |
Q | G | R | I | E | R | E | I | S | Y | L | R | L | L | R | H | P | H | I |
| Template Known Secondary structure |   |
|
| B |
|
|
| B |
| S |
|
|
|  |  |  |  |  |
| T | T | T |
|
|  | . | . |  |  |  |  |  |  |
| S |
|
|
| . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | B |
| Template Predicted Secondary structure |   |
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  | . | . |  |  |  |  |  |  |
|  |  |  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
49 | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | |
|
. | . | . | . | . | . | . | 80 | . | . | . | |
|
|
|
. | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . |
|   |
|   |   |
427 | . | . | 430 | . | . | . | . | . | . | |
. | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | R | M | I | G | I | C | E | A | E | . |
S | W | M | L | V | M | E | M | A | E | L | G | P | L | N | K | Y | L | Q | Q | N | R | H | I | K | D | K | N | I | I | E | L | V | H | Q | V | S | M | G | M | K | Y | L | E | E | S | N | F | V |
| Query Conservation |   |
|   |   |   |
|   |   |   |   |   | . |   |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|
|   |   |   |
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
I | K | L | Y | D | V | I | K | S | K | D | E | I | I | M | V | I | E | Y | A | . |
G | N | E | L | F | D | Y | I | V | Q | R | D | K | M | S | E | Q | E | A | R | R | F | F | Q | Q | I | I | S | A | V | E | Y | C | H | R | H | K | I | V |
| Template Known Secondary structure |   |
|
|  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  | T | S | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
| . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
116 | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | |
. | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . |
|   |
|   |   |
486 | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
H | R | D | L | A | A | R | N | V | L | L | V | T | Q | H | Y | A | K | I | S | D | F | G | L | S | K | A | L | R | A | D | E | N | Y | Y | K | A | Q | T | H | G | K | W | P | V | K | W | Y | A | P | E | C | I | N | Y | Y | K | F | S | S |
| Query Conservation |   |
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
H | R | D | L | K | P | E | N | L | L | L | D | E | H | L | N | V | K | I | A | D | F | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | S | P | N | Y | A | A | P | E | V | I | S | G | P |
| Template Known Secondary structure |   |
|
|
|
| S | G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
| S | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
| T | T |
|
|  |  |  |  |
|
| T |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
175 | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . |
|   |
|   |   |
546 | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | S | D | V | W | S | F | G | V | L | M | W | E | A | F | S | Y | G | Q | K | P | Y | R | G | M | K | G | S | E | V | T | A | M | L | E | K | G | E | R | M | G | C | P | A | G | C | P | R | E | M | Y | D | L | M | N | L | C | W | T | Y |
| Query Conservation |   |
  |
|
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|
|
|
|   |
|   |   |   |
|
|
|   |   | . |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |
| Template Sequence |   |
E | V | D | V | W | S | C | G | V | I | L | Y | V | M | L | C | . |
R | R | L | P | F | D | D | E | S | I | P | V | L | F | K | N | I | S | N | G | . |
V | Y | T | L | P | K | F | L | S | P | G | A | A | G | L | I | K | R | M | L | I | V |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
|
| S | S |  |  |  |  |  |  |  |  |  |  | T | . |
|
|
|
|
| T | T | S |
|  |  |  |  |  |  |  |  |  |  | S |
| S |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
232 | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | |
. | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | |
. | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
606 | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | V | E | N | R | P | G | F | T | A | V | E | L | R | L | R | N | Y | Y | Y | D | V |
| Query Conservation |   |
  |
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|   |   |
|
|
|   |   |
|
| . | . | . |
|   |
|
|   |
|   |   |
| Template Sequence |   |
N | P | L | N | R | I | S | I | H | E | I | . |
. |
. |
M | Q | D | D | W | F | K | V |
| Template Known Secondary structure |   |
S | G | G | G | S |
|
|  |  |  |  | . | . | . | T | T |
|  |  |  |  | T |
| Template Predicted Secondary structure |   |
|  |  |  |
|
|
|  |  |  |  | . | . | . |  |
|
|  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
290 | . | . | . | . | . | . | . | . | . | 300 | |
|
|
. | . | . | . | . | . | . | . |
|   |