Job Description P48025 Confidence 100.00% Date Wed Jul 10 14:17:05 BST 2013 Rank 179 Aligned Residues 256 % Identity 24% Template c3eqiA_ PDB info PDB header:transferase Chain: A: PDB Molecule:dual specificity mitogen-activated protein kinase kinase 1; PDBTitle: x-ray structure of the human mitogen-activated protein kinase kinase 12 (mek1) in a binary complex with adp and mg2p Resolution 1.90 Å

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		365	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	L	E	D	N	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P
Query Conservation
Alig confidence																										.	.													.
Template Conservation																										.	.													.
Template Sequence		F	E	K	I	S	E	L	G	A	G	N	G	G	V	V	F	K	V	S	H	K	P	S	G	.	.	L	V	M	A	R	K	L	I	H	L	E	I	.	K	P	A	I	R	N	Q	I	I	R	E	L	Q	V	L	H	E	C	N	S	P
Template Known Secondary structure												S	S									T	T	T	T	.	.													.													G	G	G	G	G				T
Template Predicted Secondary structure																										.	.													.
Template SS confidence
		68	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.			.	.	.	.	.	.	.	.	100	.	.	.		.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.
		425	.	.	.	.	430	.	.	.		.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.
Predicted Secondary structure											.																																																		.
Query SS confidence											.																																																		.
Query Sequence		Y	I	V	R	M	I	G	I	C	.	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q	N	R	H	I	K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	.
Query Conservation											.																																																		.
Alig confidence											.																																																		.
Template Conservation
Template Sequence		Y	I	V	G	F	Y	G	A	F	Y	S	D	G	E	I	S	I	C	M	E	H	M	D	G	G	S	L	D	Q	V	L	K	K	A	G	R	I	P	E	Q	I	L	G	K	V	S	I	A	V	I	K	G	L	T	Y	L	R	E	K	H
Template Known Secondary structure		T	B										T	T										T	T		B									S	S
Template Predicted Secondary structure
Template SS confidence
		125	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.
		483	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K
Query Conservation
Alig confidence																																			.	.	.	.	.
Template Conservation																																			.	.	.	.	.
Template Sequence		K	I	M	H	R	D	V	K	P	S	N	I	L	V	N	S	R	G	E	I	K	L	C	D	F	G	V	S	G	Q	L	I	D	.	.	.	.	.	S	M	A	N	S	F	V	G	T	R	S	Y	M	S	P	E	R	L	Q	G	T	H
Template Known Secondary structure						S			S	G	G	G					T	T	S																.	.	.	.	.				T	T						T	T							T	T
Template Predicted Secondary structure																																			.	.	.	.	.
Template SS confidence
		185	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.						.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.
		543	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.														.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	G	S	.	.	.	.	.	.	.	.	.	.	.	.	.	E	V	T	A	M	L	E	K	G	E	R	M	G	C	P	A
Query Conservation																																	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																					.												.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																					.
Template Sequence		Y	S	V	Q	S	D	I	W	S	M	G	L	S	L	V	E	M	A	V	.	G	R	Y	P	I	P	P	P	D	A	K	E	L	E	L	M	F	G	C	P	M	A	I	F	E	L	L	D	Y	I	V	N	E	P	P	P	K	L	P	S
Template Known Secondary structure			S																		.	T	S			S	S													.														S							T
Template Predicted Secondary structure																					.
Template SS confidence
		240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.		.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.
			590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.			.	620	.	.	.	.	.	.	.	.	.
Predicted Secondary structure		.																														.	.
Query SS confidence		.																														.	.
Query Sequence		.	G	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	T	A	V	E	L	.	.	R	L	R	N	Y	Y	Y	D	V	V	N
Query Conservation		.																														.	.
Alig confidence		.																														.	.
Template Conservation
Template Sequence		G	V	F	S	L	E	F	Q	D	F	V	N	K	C	L	I	K	N	P	A	E	R	A	D	L	K	Q	L	M	V	H	A	F	I	K	R	S	D	A	E	E	V	D
Template Known Secondary structure		T	T	S														S	S	T	T	T	S								T	S									S
Template Predicted Secondary structure
Template SS confidence
		328	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D