Return to main results Retrieve Phyre Job Id

Job DescriptionP48025
Confidence100.00%DateWed Jul 10 14:17:05 BST 2013
Rank79Aligned Residues254
% Identity28%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   355....360.........370.........380.........390.........400.........410....
Predicted Secondary structure 
















Query SS confidence 



























































Query Sequence  KEVYLDRSLLTLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
Query Conservation                  

 
 

 
             



 
               
Alig confidence 











.



















.....





















Template Conservation     

    
  .   

 
 

 

       .....



                 
Template Sequence  DDWEIPDGQITV. GQRIGSGSFGTVYKGKWHGD. . . . . VAVKMLNVTAPTPQQLQAFKNE
Template Known Secondary structure 


B

TT

.TTSSS.....

SSS

Template Predicted Secondary structure 








.




.....




Template SS confidence 



























































   448.450......... 460.........470......... 480.........490.........500.
 
   415....420.........430.........440.........450......... 460.........470...
Predicted Secondary structure 
















.

Query SS confidence 












































.













Query Sequence  ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRH. IKDKNIIELVHQVS
Query Conservation    

  
 
  

   
        

 
    


   
     .           

 
Alig confidence 












































.













Template Conservation     
  
 




            
  
      
                        
Template Sequence  VGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTA
Template Known Secondary structure  TT


TTB


SSS


SS
BTS




Template Predicted Secondary structure 































Template SS confidence 



























































   502.......510.........520.........530.........540.........550.........560.
 
   474.....480.........490.........500.........510.........520.........530...
Predicted Secondary structure 


































Query SS confidence 



























































Query Sequence  MGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWY
Query Conservation   

 


   






  



      

 




                  
    
Alig confidence 







































.............






Template Conservation                                          .............       
Template Sequence  QGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVL. . . . . . . . . . . . . SGSILWM
Template Known Secondary structure  TT
B
S

SGGGTTT


TT
B

.............



TT
Template Predicted Secondary structure 





























.............






Template SS confidence 



























































   562.......570.........580.........590.........600. .......
 
   534.....540.. .......550.........560.........570.... .....580......
Predicted Secondary structure 



...











.





...
Query SS confidence 








. . .































.











. . .
Query Sequence  APECINYYK. . . FSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSE. VTAMLEKGERMG. . .
Query Conservation 


      ...    




 

 
 
  
 
  
        .    
       ...
Alig confidence 








...


















.











.











...
Template Conservation   

              





 






.
  

            
          
Template Sequence  APEVIRMQDKNPYSFQSDVYAFGIVLYELMT. GQLPYSNINNRDQIIFMVGRGYLSPDLS
Template Known Secondary structure 
TT
SS


S.SS
TTTT


TS



GG
Template Predicted Secondary structure 












.
















Template SS confidence 



























































   621........630.........640.........650. ........660.........670.........
 
   587..590.........600.........610.........620........
Predicted Secondary structure  .













Query SS confidence  .









































Query Sequence  . CPAGCPREMYDLMNLCWTYDVENRPGFTAVELRLRNYYYDVV
Query Conservation  . 
   
     
   
    
  


   
   
        
Alig confidence  .









































Template Conservation              

  

  

  


  

   
  
   

Template Sequence  KVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLP
Template Known Secondary structure  GS
TTS
T
SSGGGS

T

Template Predicted Secondary structure 














Template SS confidence 










































   680.........690.........700.........710.........720..
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions
Phyre2 is part of Genome3D