Job Description P48025 Confidence 100.00% Date Wed Jul 10 14:17:05 BST 2013 Rank 9 Aligned Residues 340 % Identity 36% Template c3cblA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps; PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide Resolution 1.75 Å Model Dimensions (Å) X:89.578 Y:60.840 Z:45.941

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		163	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	K	M	P	W	F	H	G	N	I	S	R	D	E	S	E	Q	T	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	D	N	S	G	S	Y	A	L	C	L	L	H	E	G	K	V	L	H	Y	R	I	D	R	D	K	T
Query Conservation
Alig confidence																							.	.	.	.												.	.																.	.	.	.	.	.	.
Template Conservation																							.	.	.	.												.	.																.	.	.	.	.	.	.
Template Sequence		H	E	Q	L	W	Y	H	G	A	I	P	R	A	E	V	A	E	L	L	V	H	.	.	.	.	S	G	D	F	L	V	R	E	S	Q	Q	.	.	E	Y	V	L	S	V	P	R	H	F	I	I	N	L	Y	.	.	.	.	.	.	.
Template Known Secondary structure		G	G		T	T	B		T	T												S	.	.	.	.	T	T										.	.																.	.	.	.	.	.	.
Template Predicted Secondary structure																							.	.	.	.												.	.																.	.	.	.	.	.	.
Template SS confidence
		456	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.					.	.	.	480	.	.	.	.	.	.	.			.	.	490	.	.	.	.	.	.	.	.	.	500	.	.
		223	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	K	L	S	I	P	E	G	K	K	F	D	T	L	W	Q	L	V	E	H	Y	S	Y	K	P	D	G	L	L	R	V	L	T	V	P	C	Q	K	I	G	A	Q	M	G	H	P	G	S	P	N	A	H	P	V	T	W	S	P	G	G
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	R	L	F	P	S	I	P	L	L	I	D	H	L	L	S	T	Q	Q	P	L	V	V	L	H	R	A	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.					S												T										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
										514	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.
		283	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	I	S	R	I	K	S	Y	S	F	P	K	P	G	H	K	K	P	A	P	P	Q	G	S	R	P	E	S	T	V	S	F	N	P	Y	E	P	T	G	G	P	W	G	P	D	R	G	L	Q	R	E	A	L	P	M	D	T	E	V	Y
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		343	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	S	P	Y	A	D	P	E	E	I	R	P	K	E	V	Y	L	D	R	S	L	L	T	L	E	D	N	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.																.																								.	.								.
Template Conservation		.	.	.	.	.	.	.	.	.																.																								.	.								.
Template Sequence		.	.	.	.	.	.	.	.	.	V	P	K	D	K	W	V	L	N	H	E	D	L	V	L	.	G	E	Q	I	G	R	G	N	F	G	E	V	F	S	G	R	L	R	A	D	N	T	L	.	.	V	A	V	K	S	C	R	.	E	T
Template Known Secondary structure		.	.	.	.	.	.	.	.	.					T	T	B			G	G	G				.								T	T									T	T	T				.	.								.	T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.																.																								.	.								.
Template SS confidence
											549	550	.	.	.	.	.	.	.	.	.	560	.	.	.		.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.			.	.	.	590	.	.	.		.	.
		403	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.		.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.		.	.	.	.	.	460
Predicted Secondary structure																																	.																						.
Query SS confidence																																	.																						.
Query Sequence		N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I	C	.	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	.	Q	Q	N	R	H	I
Query Conservation																																	.																						.
Alig confidence																																	.																						.
Template Conservation
Template Sequence		L	P	P	D	L	K	A	K	F	L	Q	E	A	R	I	L	K	Q	Y	S	H	P	N	I	V	R	L	I	G	V	C	T	Q	K	Q	P	I	Y	I	V	M	E	L	V	Q	G	G	D	F	L	T	F	L	R	T	E	G	A	R	L
Template Known Secondary structure		S						T	T	T	T							T	T				T	T	B									S	S	S	S									T	T		B									G	G	G
Template Predicted Secondary structure
Template SS confidence
		596	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.
		461	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520
Predicted Secondary structure
Query SS confidence
Query Sequence		K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	V	K	T	L	L	Q	M	V	G	D	A	A	A	G	M	E	Y	L	E	S	K	C	C	I	H	R	D	L	A	A	R	N	C	L	V	T	E	K	N	V	L	K	I	S	D	F	G	M	S	R	E	E	A	D	G	V	Y	A	A
Template Known Secondary structure																							T	T				S			S	G	G	G					T	T								G	G	G					T	T	S
Template Predicted Secondary structure
Template SS confidence
		656	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.
		521	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580
Predicted Secondary structure
Query SS confidence
Query Sequence		K	A	Q	T	H	G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	G	S	E	V	T	A	M	L	E
Query Conservation
Alig confidence									.
Template Conservation									.
Template Sequence		S	G	G	L	R	Q	V	.	P	V	K	W	T	A	P	E	A	L	N	Y	G	R	Y	S	S	E	S	D	V	W	S	F	G	I	L	L	W	E	T	F	S	L	G	A	S	P	Y	P	N	L	S	N	Q	Q	T	R	E	F	V	E
Template Known Secondary structure			S	S					.		G	G	G	S																												T	T	S			S	S	T	T	S
Template Predicted Secondary structure									.
Template SS confidence
		716	.	.	.	720	.	.		.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.
		581	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	G	E	R	M	G	C	P	A	G	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	T	A	V	E	L	R	L	R	N	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		K	G	G	R	L	P	C	P	E	L	C	P	D	A	V	F	R	L	M	E	Q	C	W	A	Y	E	P	G	Q	R	P	S	F	S	T	I	Y	Q	E	L	Q	S	I
Template Known Secondary structure		T	T							T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		775	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.