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Job DescriptionP48025
Confidence100.00%DateWed Jul 10 14:17:05 BST 2013
Rank238Aligned Residues245
% Identity33%Templatec2xbaA_
PDB info PDB header:transferaseChain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of human anaplastic lymphoma kinase in complex2 with pha-e429
Resolution1.95 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   369370...... ...380.........390.........400.........410.........420....
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Query Sequence  NELGSGNF. . . . GTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNP
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Template Sequence  KEVPRKNITLIRGLVYEGQV. . . . SPLQVAVKTLP. EVCSEQDELDFLMEALIISKFNHQ
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   11091110.........1120........ .1130......... 1140.........1150.........1160...
 
   425....430... ......440.........450......... 460.........470......
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Query Sequence  YIVRMIGIC. EAESWMLVMEMAELGPLNKYLQQNRH. . . . . . . IKDKNIIELVHQVSMGM
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Template Sequence  NIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGC
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   1178.1180.........1190.........1200.........1210.........1220.........1230.......
 
   477..480.........490.........500.........510.........520.........530......
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Query Sequence  KYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPE
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Template Sequence  QYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFG. . . . . . . . MARDIYAMLPVKWMPPE
Template Known Secondary structure  TT


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   1238.1240.........1250.........1260.........1270.. .......1280.........
 
   537..540.........550.........560.........570.........580.........590......
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Query Sequence  CINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMY
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Template Sequence  AFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVY
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   1300.........1310.........1320.........1330.........1340.........1350.........
 
   597..600.........610.........620......
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Query Sequence  DLMNLCWTYDVENRPGFTAVELRLRNYYYD
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Template Sequence  RIMTQCWQHQPEDRPNFAIILERIEYCTQD
Template Known Secondary structure  T
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   1360.........1370.........1380.........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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