Job Description P48025 Confidence 100.00% Date Wed Jul 10 14:17:05 BST 2013 Rank 123 Aligned Residues 249 % Identity 23% Template c2r7bA_ PDB info PDB header:signaling protein, transferase Chain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor Resolution 2.70 Å

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		365	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.		.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.
Predicted Secondary structure																																								.
Query SS confidence																																								.
Query Sequence		T	L	E	D	N	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	.	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N
Query Conservation																																								.
Alig confidence																												.	.											.
Template Conservation																												.	.
Template Sequence		F	K	F	G	K	I	L	G	E	G	S	F	S	T	V	V	L	A	R	E	L	A	T	S	R	E	.	.	Y	A	I	K	I	L	E	K	R	H	I	I	K	E	N	K	V	P	Y	V	T	R	E	R	D	V	M	S	R	L	D	H
Template Known Secondary structure												S	S									T	T	T				.	.														T	T														T
Template Predicted Secondary structure																												.	.
Template SS confidence
		82	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.			.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.
		424	.	.	.	.	.	430	.	.	.	.	.	.	.		.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.
Predicted Secondary structure																.
Query SS confidence																.
Query Sequence		P	Y	I	V	R	M	I	G	I	C	E	A	E	S	.	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q	N	R	H	I	K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S
Query Conservation																.
Alig confidence																.
Template Conservation
Template Sequence		P	F	F	V	K	L	Y	F	T	F	Q	D	D	E	K	L	Y	F	G	L	S	Y	A	K	N	G	E	L	L	K	Y	I	R	K	I	G	S	F	D	E	T	C	T	R	F	Y	T	A	E	I	V	S	A	L	E	Y	L	H	G	K
Template Known Secondary structure		T	T	B										S	S										T	T		B								S	S	S																							T
Template Predicted Secondary structure
Template SS confidence
		140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.
		483	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K
Query Conservation
Alig confidence																																					.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																					.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		G	I	I	H	R	D	L	K	P	E	N	I	L	L	N	E	D	M	H	I	Q	I	T	D	F	G	T	A	K	V	L	F	V	G	T	.	.	.	.	.	.	.	.	.	.	.	.	A	Q	Y	V	S	P	E	L	L	T	E	K	S
Template Known Secondary structure		T								T	T	T					T	T	S								T	T									.	.	.	.	.	.	.	.	.	.	.	.	G	G	G								S	S
Template Predicted Secondary structure																																					.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.													.	.	.	.	.	240	.	.	.	.	.	.	.
		543	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	G	S	E	V	T	A	M	L	E	K	G	E	R	M	G	C	P	A	G	C	P	R	E	M	Y	D	L	M	N	L	C
Query Conservation
Alig confidence																					.																						.
Template Conservation																					.																						.
Template Sequence		A	C	K	S	S	D	L	W	A	L	G	C	I	I	Y	Q	L	V	A	.	G	L	P	P	F	R	A	G	N	E	Y	L	I	F	Q	K	I	I	K	L	E	.	Y	D	F	P	E	K	F	F	P	K	A	R	D	L	V	E	K	L
Template Known Secondary structure																					.	S	S		S				S	S											T		.					S	S	S										T	T
Template Predicted Secondary structure																					.																						.
Template SS confidence
		259	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.		.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.		.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.
		603	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.				.	620	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																		.	.	.
Query SS confidence																		.	.	.
Query Sequence		W	T	Y	D	V	E	N	R	P	G	F	T	A	V	E	L	.	.	.	R	L	R	N	Y	Y	Y	D	V	V	N
Query Conservation																		.	.	.
Alig confidence																		.	.	.
Template Conservation
Template Sequence		L	V	L	D	A	T	K	R	L	G	C	E	E	M	E	G	Y	G	P	L	K	A	H	P	F	F	E	S	V	T
Template Known Secondary structure		S		S	S	T	T	S	S	T	T	S	G	G	G	T	T							S	G	G	G	T	T
Template Predicted Secondary structure
Template SS confidence
		317	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D