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Job DescriptionP48025
Confidence100.00%DateWed Jul 10 14:17:05 BST 2013
Rank2Aligned Residues532
% Identity59%Templatec2ozoA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
Resolution2.60 Å
Model Dimensions (Å)X:86.096 Y:86.949 Z:57.174

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   7..10.........20.........30.........40.........50.........60......
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Query Sequence  DSANHLTYFFGNITREEAEDYLVQGGMTDGLYLLRQSRNYLGGFALSVAHNRKAHHYTIE
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Template Conservation         
 

 


  

  
   
  

 



 
    
   

      
 
  
 
Template Sequence  DPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIE
Template Known Secondary structure 
TTSS
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TT
TTBTT
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   3......10.........20.........30.........40.........50.........60..
 
   67..70.........80.........90.........100.........110.........120......
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Query Sequence  RELNGTYAISGGRAHASPADLCHYHSQEPDGLICLLKKPFNRPPGVQPKTGPFEDLKENL
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Template Conservation          
     
 

  

  
      
   
  

  
                 
Template Sequence  RQLNGTYAIAGGKAHCGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAM
Template Known Secondary structure 
TTS
TTS

BSSTS

TTSSS


SB



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B

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   63......70.........80.........90.........100.........110.........120..
 
   127..130.........140.........150.........160.........170.........180......
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Query Sequence  IREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGNISRDESEQTVLIGSK
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Template Sequence  VRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAERKLYSGAQ
Template Known Secondary structure 


TTS
TTTSTTB
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   123......130.........140.........150.........160.........170.........180..
 
   187..190.........200.........210.........220.........230.........240......
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Query Sequence  TNGKFLIRARDNSGSYALCLLHEGKVLHYRIDRDKTGKLSIPEGKKFDTLWQLVEHYSYK
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Template Sequence  TDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLKLK
Template Known Secondary structure 
TT

SSTTTT
TT


TTS
SS
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   183......190.........200.........210.........220.........230.........240..
 
   247..250.........260.........270.........280.........290.........300......
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Query Sequence  PDGLLRVLTVPCQKIGAQMGHPGSPNAHPVTWSPGGIISRIKSYSFPKPGHKKPAPPQGS
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Template Conservation     
   
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Template Sequence  ADGLIYCLKEACPN. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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TT
SS


SB


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   243......250......
 
   307..310.........320.........330.........340.........350.........360......
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Query Sequence  RPESTVSFNPYEPTGGPWGPDRGLQREALPMDTEVYESPYADPEEIRPKEVYLDRSLLTL
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Template Conservation  ..............................                              
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . MDTSVFESPFSDPEELKDKKLFLKRDNLLI
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S
SSSSS
S
SS



SB

TTS
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   310.........320.........330.........
 
   367..370.........380.........390.........400.........410.........420......
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Query Sequence  EDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYI
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Template Sequence  ADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKAD. TEEMMREAQIMHQLDNPYI
Template Known Secondary structure 
SSS
SS





SSTT.TT


TTB
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   340.........350.........360.........370......... 380.........390........
 
   427..430.........440.........450.... .....460.........470.........480.....
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Query Sequence  VRMIGICEAESWMLVMEMAELGPLNKYL. QQNRHIKDKNIIELVHQVSMGMKYLEESNFV
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Template Conservation 
   
        

 
    


   
                 

   
  

    
Template Sequence  VRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFV
Template Known Secondary structure 

SSS

TT
BTT
TTTS
TT

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   399400.........410.........420.........430.........440.........450........
 
   486...490.........500.........510.........520.........530.........540.....
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Query Sequence  HRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSS
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Template Sequence  HRNLAARNVLLVNRHYAKISDFGLSKAL. . . . . . . . . . . . . . GPLKWYAPECINFRKFSS
Template Known Secondary structure 
S

SGGGTT


STTTT
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TTS




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   459460.........470.........480...... ...490.........500....
 
   546...550.........560.........570.........580.........590.........600.....
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Query Sequence  KSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTY
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Template Conservation   




 
  
 
  
 
  
            
        
   
     

  
   
Template Sequence  RSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIY
Template Known Secondary structure  TTS

TTTT

STT





TT

TT
S
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   519520.........530.........540.........550.........560.........570........
 
   606...610.........620.........
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Query Sequence  DVENRPGFTAVELRLRNYYYDVVN
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Template Conservation   
  

    
   
         
Template Sequence  KWEDRPDFLTVEQRMRACYYSLAS
Template Known Secondary structure  STTTS

S
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   579580.........590.........600..
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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