Job Description P48025 Confidence 100.00% Date Wed Jul 10 14:17:05 BST 2013 Rank 8 Aligned Residues 355 % Identity 38% Template c2c0iA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 Resolution 2.30 Å Model Dimensions (Å) X:67.796 Y:75.310 Z:54.081

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		163	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.		.	.	.	200	.	.	.	.	.	.	.						.	.	210	.	.	.	.	.	.
Predicted Secondary structure																																				.												.	.	.	.	.
Query SS confidence																																				.												.	.	.	.	.
Query Sequence		E	K	M	P	W	F	H	G	N	I	S	R	D	E	S	E	Q	T	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	.	D	N	S	G	S	Y	A	L	C	L	L	.	.	.	.	.	H	E	G	K	V	L	H	Y	R
Query Conservation																																				.												.	.	.	.	.
Alig confidence																																				.												.	.	.	.	.
Template Conservation
Template Sequence		E	T	E	E	W	F	F	K	G	I	S	R	K	D	A	E	R	Q	L	L	A	P	G	N	M	L	G	S	F	M	I	R	D	S	E	T	T	K	G	S	Y	S	L	S	V	R	D	Y	D	P	R	Q	G	D	T	V	K	H	Y	K
Template Known Secondary structure		G	G	S	T	T			T	T											T	S	T	T			T	T								S	S	S	T	T											T	T	T
Template Predicted Secondary structure
Template SS confidence
		119	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.
		217	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	D	R	D	K	T	G	K	L	S	I	P	E	G	K	K	F	D	T	L	W	Q	L	V	E	H	Y	S	Y	K	P	D	G	L	L	R	V	L	T	V	P	C	Q	K	I	G	A	Q	M	G	H	P	G	S	P	N	A	H	P	V
Query Conservation
Alig confidence																																																.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		I	R	T	L	D	N	G	G	F	Y	I	S	P	R	S	T	F	S	T	L	Q	E	L	V	D	H	Y	K	K	G	N	D	G	L	C	Q	K	L	S	V	P	C	M	S	S	K	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure			B			S	T	T				S	S	T	T	S			S	S								T	T	S	S		S	S		S	S				S	B						.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		179	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.
		277	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	W	S	P	G	G	I	I	S	R	I	K	S	Y	S	F	P	K	P	G	H	K	K	P	A	P	P	Q	G	S	R	P	E	S	T	V	S	F	N	P	Y	E	P	T	G	G	P	W	G	P	D	R	G	L	Q	R	E	A	L	P
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		337	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	D	T	E	V	Y	E	S	P	Y	A	D	P	E	E	I	R	P	K	E	V	Y	L	D	R	S	L	L	T	L	E	D	N	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K	K	V	V	K	T	V	A	V	K
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.																				.																			.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.																				.																			.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	P	Q	K	P	W	E	K	D	A	W	E	I	P	R	E	S	L	K	L	.	E	K	K	L	G	A	G	Q	F	G	E	V	W	M	A	T	Y	N	.	.	.	K	H	T	K	V	A	V	K
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.							T	T		S	B			G	G	G				.								T	T									T	.	.	.	T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.																				.																			.	.	.
Template SS confidence
													225	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.		.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.				.	.	.	.	.	.	.	.
		397	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I	C	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q
Query Conservation
Alig confidence										.	.	.
Template Conservation										.	.	.
Template Sequence		T	M	K	P	G	S	M	S	.	.	.	V	E	A	F	L	A	E	A	N	V	M	K	T	L	Q	H	D	K	L	V	K	L	H	A	V	V	T	K	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S
Template Known Secondary structure							S	S		.	.	.													T				T	T	B									S	S	S									T	T		B							S
Template Predicted Secondary structure										.	.	.
Template SS confidence
		270	.	.	.	.	.	.	.				.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.
		457	.	.			460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.
Predicted Secondary structure					.	.
Query SS confidence					.	.
Query Sequence		N	R	H	.	.	I	K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R
Query Conservation					.	.
Alig confidence					.	.																																																					.	.	.
Template Conservation																																																											.	.	.
Template Sequence		D	E	G	S	K	Q	P	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	F	I	E	Q	R	N	Y	I	H	R	D	L	R	A	A	N	I	L	V	S	A	S	L	V	C	K	I	A	D	F	G	L	A	R	.	.	.
Template Known Secondary structure		T	T	G	G	G																							T	T				S			S	G	G	G					T	T								T	T	G	G	G	.	.	.
Template Predicted Secondary structure																																																											.	.	.
Template SS confidence
		327	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.
		515	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	G	S	E
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	V	I	P	I	K	W	T	A	P	E	A	I	N	F	G	S	F	T	I	K	S	D	V	W	S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G	M	S	N	P	E
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	T			G	G	G	S																												T	T	T			S	S	T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
														384	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.
		575	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	T	A	M	L	E	K	G	E	R	M	G	C	P	A	G	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	T	A	V	E	L	R	L	R	N	Y	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	I	R	A	L	E	R	G	Y	R	M	P	R	P	E	N	C	P	E	E	L	Y	N	I	M	M	R	C	W	K	N	R	P	E	E	R	P	T	F	E	Y	I	Q	S	V	L	D	D	F	Y
Template Known Secondary structure								T	T							T	T													T		S	S	G	G	G	S												T	T	T
Template Predicted Secondary structure
Template SS confidence
		445	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.