|   |   |
365 | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
T | L | E | D | N | E | L | G | S | G | N | F | G | T | V | K | K | G | Y | Y | Q | M | K | K | V | V | K | T | V | A | V | K | I | L | K | N | E | A | N | D | P | A | L | K | D | E | L | L | A | E | A | N | V | M | Q | Q | L | D | N | P |
| Query Conservation |   |
  |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   | . | . |
|
|
|
|   |
|   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|
|
| Template Sequence |   |
F | E | E | I | A | V | L | G | Q | G | A | F | G | Q | V | V | K | A | R | N | A | L | D | S | R | Y | . |
. |
Y | A | I | K | K | I | R | H | T | . |
. |
. |
E | E | K | L | S | T | I | L | S | E | V | M | L | L | A | S | L | N | H | Q |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | T | T | T |
|
|  | . | . |  |  |  |  |  |  |  |  |
| . | . | . |  |  |  |  | T | T | T |  |  |  |  |  |  |  | T | T |
|
|
| T |
| Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  | . | . |  |  |  |  |  |  |
|
|
| . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
599 | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | |
|
. | . | . | . | . | 630 | . | . | . | |
|
|
. | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . |
|   |
|   |   |
425 | . | . | . | . | 430 | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | |
. | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | I | V | R | M | I | G | I | C | E | . |
. |
. |
. |
. |
. |
. |
A | E | S | W | M | L | V | M | E | M | A | E | L | G | P | L | N | K | Y | L | Q | Q | N | R | . |
H | I | K | D | K | N | I | I | E | L | V | H | Q | V | S | M | G | M |
| Query Conservation |   |
  |
|
|   |   |   |
|   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
| Template Sequence |   |
Y | V | V | R | Y | Y | A | A | W | L | E | R | R | N | F | V | K | K | S | T | L | F | I | Q | M | E | Y | C | E | N | G | T | L | Y | D | L | I | H | S | E | N | L | N | Q | Q | R | D | E | Y | W | R | L | F | R | Q | I | L | E | A | L |
| Template Known Secondary structure |   |
T | B |
|
|  |  |  |  |  |  |  |
|
| T | T |
|
|
|  |  |  |  |  |  |  |  |
|
|
| S |
| B |  |  |  |  |  |  |  | S |
| T | T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
654 | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . |
|   |
|   |   |
477 | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | Y | L | E | E | S | N | F | V | H | R | D | L | A | A | R | N | V | L | L | V | T | Q | H | Y | A | K | I | S | D | F | G | L | S | K | A | L | R | A | D | E | N | Y | Y | K | A | Q | T | H | G | K | W | P | V | K | W | Y | A | P | E |
| Query Conservation |   |
  |
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|
| Template Sequence |   |
S | Y | I | H | S | Q | G | I | I | H | R | D | L | K | P | M | N | I | F | I | D | E | S | R | N | V | K | I | G | D | F | G | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | T | A | M | Y | V | A | T | E |
| Template Known Secondary structure |   |
 |  |  |  |  | T | T |
|
|
| S |
|
|
| G | G | G |  |  |  |
| T | T | S |
|  |  |  |
| S |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
| G | G | G |
|
| T | T |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
824 | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840 | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 860 | . | . | . | . | . |
|   |
|   |   |
537 | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | |
|
|
. | . | . | . | . | . | 590 | . | . | . |
| Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
C | I | N | Y | Y | K | F | S | S | K | S | D | V | W | S | F | G | V | L | M | W | E | A | F | S | Y | G | Q | K | P | Y | R | G | M | K | G | S | E | V | T | A | M | L | E | K | G | E | . |
. |
. |
R | M | G | C | P | A | G | C | P | R |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . | . | . |   |   |   |   |
|   |   |   |
|   |
| Alig confidence |   |
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  | . | . | . |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|   | . |
| . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
| Template Sequence |   |
V | . |
. |
. |
L | H | Y | N | E | K | I | D | M | Y | S | L | G | I | I | F | F | E | M | I | Y | . |
P | . |
. |
F | S | T | G | M | E | R | V | N | I | L | K | K | L | R | S | V | S | I | E | F | P | P | D | F | D | D | N | K | M | K |
| Template Known Secondary structure |   |
T | . | . | . |
|
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | . |
| . | . |
| S | S |  |  |  |  |  |  |  |  |  |  |  | T | S | T | T |
|
|
|
| T | T | S |
| T | T | T | T |  |
| Template Predicted Secondary structure |   |
 | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . |
| . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
895 | |
|
|
. | . | . | . | 900 | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | |
. | |
|
. | . | 920 | . | . | . | . | . | . | . | . | . | 930 | . | . | . | . | . | . | . | . | . | 940 | . | . | . | . | . | . | . | . |
|   |
|   |   |
594 | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | M | Y | D | L | M | N | L | C | W | T | Y | D | V | E | N | R | P | G | F | T | A | V | E | L |
| Query Conservation |   |
  |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |
| Template Sequence |   |
V | E | K | K | I | I | R | L | L | I | D | H | D | P | N | K | R | P | G | A | R | T | L | L | N |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T |
| S |
| G | G | G | S |
|
|  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
953 | . | . | . | . | . | . | 960 | . | . | . | . | . | . | . | . | . | 970 | . | . | . | . | . | . | . |
|   |