|   |   |
349 | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | |
|
. | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |
|
|  |  |
|
|  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
|
|
|
|
|
| . |
. |
|
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|
|
| Query Sequence |   |
P | E | E | I | R | P | K | E | V | Y | L | D | R | S | L | L | T | L | E | D | N | E | L | G | S | G | N | F | G | T | V | K | K | G | Y | Y | Q | M | K | K | . |
. |
V | V | K | T | V | A | V | K | I | L | K | N | E | A | N | D | P | A |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
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|
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|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
| Template Conservation |   |
|   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
| . | . |   |   |   |   |   |   |
| Template Sequence |   |
P | T | I | F | E | E | R | H | L | K | Y | . |
. |
. |
. |
. |
. |
. |
. |
I | S | Q | L | G | K | G | N | F | G | S | V | E | L | C | R | Y | D | P | L | G | D | N | T | G | A | L | V | A | V | K | Q | L | . |
. |
Q | H | S | G | P | D |
| Template Known Secondary structure |   |
|
| B |
|
| G | G | G |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  |
| S | S | S | S | S |
| S |
|  |  |  |  |  |  |
| . | . | S |
|
| S | T | T |
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . |
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
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|
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|
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|
|
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|
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|
|
|
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|
|
|
|   |   |
814 | . | . | . | . | . | 820 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840 | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | . | |
|
. | . | 860 | . | . | . |
|   |
|   |   |
407 | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | |
|
|
. | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | |
. | . | 460 | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
| . |
|
|
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
| . |
. |
. |
|
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|
|
|
|
|
|
|
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|
|
|
|
|
| . |
|
|
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|
|
| Query Sequence |   |
L | K | D | E | L | L | A | E | A | N | V | M | Q | Q | L | D | N | P | Y | I | V | R | M | I | G | I | C | E | A | E | S | . |
. |
. |
W | M | L | V | M | E | M | A | E | L | G | P | L | N | K | Y | L | Q | Q | N | . |
R | H | I | K | D |
| Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   | . | . | . |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   | . |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
Q | Q | R | D | F | Q | R | E | I | Q | I | L | K | A | L | H | S | D | F | I | V | K | Y | R | G | V | S | Y | G | P | G | R | P | E | L | R | L | V | M | E | Y | L | P | S | G | C | L | R | D | F | L | Q | R | H | R | A | R | L | D | A |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | B |
|
|  |  |  |  |
|
|
| S | S | S | S |
|
|  |  |  |  |
|
|
| T | T |
| B |  |  |  |  |  |  |  | T | T | T | T |
|
|  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
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|
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|
|
|
|
|
|
|
|
|
|
|
|   |   |
864 | . | . | . | . | . | 870 | . | . | . | . | . | . | . | . | . | 880 | . | . | . | . | . | . | . | . | . | 890 | . | . | . | . | . | . | . | . | . | 900 | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | . | . | . | 920 | . | . | . |
|   |
|   |   |
463 | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | N | I | I | E | L | V | H | Q | V | S | M | G | M | K | Y | L | E | E | S | N | F | V | H | R | D | L | A | A | R | N | V | L | L | V | T | Q | H | Y | A | K | I | S | D | F | G | L | S | K | A | L | R | A | D | E | N | Y | Y | K | A |
| Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |
| Template Sequence |   |
S | R | L | L | L | Y | S | S | Q | I | C | K | G | M | E | Y | L | G | S | R | R | C | V | H | R | D | L | A | A | R | N | I | L | V | E | S | E | A | H | V | K | I | A | D | F | G | L | A | K | L | L | P | L | D | K | . |
. |
D | V | V |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
| S |
|
|
| G | G | G |  |  |  |  |  | T | T |  |  |  |  |
|
|
| S | S |
|  |  |
|
| T | T |
| . | . |
|
|
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
|
|
|
|
|
|   |   |
924 | . | . | . | . | . | 930 | . | . | . | . | . | . | . | . | . | 940 | . | . | . | . | . | . | . | . | . | 950 | . | . | . | . | . | . | . | . | . | 960 | . | . | . | . | . | . | . | . | . | 970 | . | . | . | . | . | . | . | . | |
|
. | 980 | . |
|   |
|   |   |
523 | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | |
|
|
|
|
|
|
|
|
|
|
|
| Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
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|
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|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Query Sequence |   |
Q | T | H | G | K | W | P | V | K | W | Y | A | P | E | C | I | N | Y | Y | K | F | S | S | K | S | D | V | W | S | F | G | V | L | M | W | E | A | F | S | Y | G | Q | K | P | Y | R | G | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |
|   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
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|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|   |
|
|
|   | . |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
R | E | P | G | Q | S | P | I | F | W | Y | A | P | E | S | L | S | D | N | I | F | S | R | Q | S | D | V | W | S | F | G | V | V | L | Y | E | L | F | T | . |
Y | C | D | K | S | C | S | P | S | A | E | F | L | R | M | M | G | C | E | R |
| Template Known Secondary structure |   |
S | S |
|
| S | S |
| G | G | G | S |
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | T | T |
| S | T | T | S |  |  |  |  |  |  |  |  |  |
|
| S | S |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|   |   |
984 | . | . | . | . | . | 990 | . | . | . | . | . | . | . | . | . | 1000 | . | . | . | . | . | . | . | . | . | 1010 | . | . | . | . | . | . | . | . | . | 1020 | . | . | |
. | . | . | . | . | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . |
|   |
|   |   |
|
|
|
571 | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . |
| Predicted Secondary structure |   |
. | . | . |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
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|
|
|
|
|
| Query Sequence |   |
. |
. |
. |
K | G | S | E | V | T | A | M | L | E | K | G | E | R | M | G | C | P | A | G | C | P | R | E | M | Y | D | L | M | N | L | C | W | T | Y | D | V | E | N | R | P | G | F | T | A | V | E | L | R | L | R | N | Y | Y |
| Query Conservation |   |
. | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |
| Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
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| Template Conservation |   |
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| Template Sequence |   |
D | V | P | A | L | C | R | L | L | E | L | L | E | E | G | Q | R | L | P | A | P | P | A | C | P | A | E | V | H | E | L | M | K | L | C | W | A | P | S | P | Q | D | R | P | S | F | S | A | L | G | P | Q | L | D | M | L | W |
| Template Known Secondary structure |   |
S |
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| T | T |
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| S | S | G | G | G | S |
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| Template Predicted Secondary structure |   |
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| Template SS confidence |   |
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|   |   |
1043 | . | . | . | . | . | . | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080 | . | . | . | . | . | . | . | . | . | 1090 | . | . | . | . | . | . | . | . | . |
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