Job Description P29351 Confidence 100.00% Date Wed Jul 10 14:09:17 BST 2013 Rank 28 Aligned Residues 254 % Identity 61% Template c3jrlA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:oncogenic tyrosine phosphatase shp2; PDBTitle: crystal structure of the oncogenic tyrosine phosphatase shp2 complexed2 with a salicylic acid-based small molecule inhibitor Resolution 2.00 Å

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		260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	Q	R	L	E	G	Q	R	P	E	N	K	S	K	N	R	Y	K	N	I	L	P	F	D	H	S	R	V	I	L	Q	G	R	D	S	N	I	P	G	S	D	Y	I	N	A	N	Y	V	K	N	Q	L	L	G	P	D	E	N	S	K
Query Conservation
Alig confidence																																																				.	.	.	.	.	.	.	.
Template Conservation																																																				.	.	.	.	.	.	.	.
Template Sequence		Y	S	R	K	E	G	Q	R	Q	E	N	K	N	K	N	R	Y	K	N	I	L	P	F	D	H	T	R	V	V	L	H	D	G	D	P	N	E	P	V	S	D	Y	I	N	A	N	I	I	M	P	.	.	.	.	.	.	.	.	K	K
Template Known Secondary structure						G	G	G	S	G	G	G	G	G	G		S	S	T	T					T	T	T	B					S			T	T	S	S			S			S							.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																				.	.	.	.	.	.	.	.
Template SS confidence
		263	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.									.	.
		320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	Y	I	A	S	Q	G	C	L	D	A	T	V	N	D	F	W	Q	M	A	W	Q	E	N	T	R	V	I	V	M	T	T	R	E	V	E	K	G	R	N	K	C	V	P	Y	W	P	E	V	G	T	Q	R	V	Y	G	L	Y	S	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	Y	I	A	T	Q	G	C	L	Q	N	T	V	N	D	F	W	R	M	V	F	Q	E	N	S	R	V	I	V	M	T	T	K	E	V	E	R	G	K	S	K	C	V	K	Y	W	P	D	E	Y	A	L	K	E	Y	G	V	M	R	V
Template Known Secondary structure											T	T	T											T	T								S		S			T	T								S			T	T						T	T
Template Predicted Secondary structure
Template SS confidence
		326	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.
		380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	N	S	R	E	H	D	T	A	E	Y	K	L	R	T	L	Q	I	S	P	L	D	N	G	D	L	V	R	E	I	W	H	Y	Q	Y	L	S	W	P	D	H	G	V	P	S	E	P	G	G	V	L	S	F	L	D	Q	I	N	Q	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	N	V	K	E	S	A	A	H	D	Y	T	L	R	E	L	K	L	S	K	V	G	Q	G	N	T	E	R	T	V	W	Q	Y	H	F	R	T	W	P	D	H	G	V	P	S	D	P	G	G	V	L	D	F	L	E	E	V	H	H	K
Template Known Secondary structure										S	S											T	T		S	S															S	S	S			S	S	T
Template Predicted Secondary structure
Template SS confidence
		386	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.
		440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	E	S	L	P	H	A	G	P	I	I	V	H	C	S	A	G	I	G	R	T	G	T	I	I	V	I	D	M	L	M	E	S	I	S	T	K	G	L	D	C	D	I	D	I	Q	K	T	I	Q	M	V	R	A	Q	R	S	G	M	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Q	E	S	I	M	D	A	G	P	V	V	V	H	C	S	A	G	I	G	R	T	G	T	F	I	V	I	D	I	L	I	D	I	I	R	E	K	G	V	D	C	D	I	D	V	P	K	T	I	Q	M	V	R	S	Q	R	S	G	M	V
Template Known Secondary structure				T	S	T	T									S	S	S	S	S																				T	T	S													T	T	S	T	T		S
Template Predicted Secondary structure
Template SS confidence
		446	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.
		500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	T	E	A	Q	Y	K	F	I	Y	V	A	I	A	Q	F	I	E	T	T	K	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Q	T	E	A	Q	Y	R	F	I	Y	M	A	V	Q	H	Y	I	E	T	L	Q	R
Template Known Secondary structure			S																			T
Template Predicted Secondary structure
Template SS confidence
		506	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D