Job Description P29351 Confidence 100.00% Date Wed Jul 10 14:09:17 BST 2013 Rank 21 Aligned Residues 292 % Identity 33% Template c2vexA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 1; PDBTitle: crystal strucutre of protein tyrosine phosphatase 1b in2 complex with an isothiazolidinone-containing inhibitor Resolution 2.20 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		223	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	E	N	R	V	L	E	L	N	K	K	Q	E	S	E	D	T	A	K	A	G	F	W	E	E	F	E	S	L	Q	K	Q	E	V	K	N	L	H	Q	R	L	E	G	Q	R	P	E	N	K	S	K	N	R	Y	K	N	I	L	P	F
Query Conservation
Alig confidence												.	.	.	.	.	.	.	.																			.	.
Template Conservation												.	.	.	.	.	.	.	.																			.	.
Template Sequence		M	E	K	E	F	E	Q	I	D	K	.	.	.	.	.	.	.	.	S	G	S	W	A	A	I	Y	Q	D	I	R	H	E	A	S	D	F	.	.	P	C	R	V	A	K	L	P	K	N	K	N	R	N	R	Y	R	D	V	S	P	F
Template Known Secondary structure												.	.	.	.	.	.	.	.		T													S				.	.			T	T	T	T	S	G	G	G	G	G	G		S	S	T	T
Template Predicted Secondary structure												.	.	.	.	.	.	.	.																			.	.
Template SS confidence
		3	.	.	.	.	.	.	10	.	.									.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30			.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.
		283	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	H	S	R	V	I	L	Q	G	R	D	S	N	I	P	G	S	D	Y	I	N	A	N	Y	V	K	N	Q	L	L	G	P	D	E	N	S	K	T	Y	I	A	S	Q	G	C	L	D	A	T	V	N	D	F	W	Q	M	A	W	Q	E
Query Conservation
Alig confidence													.	.	.	.	.													.	.	.	.	.
Template Conservation													.	.	.	.	.													.	.	.	.	.
Template Sequence		D	H	S	R	I	K	L	H	Q	E	D	.	.	.	.	.	N	D	Y	I	N	A	S	L	I	K	M	E	.	.	.	.	.	E	A	Q	R	S	Y	I	L	T	Q	G	P	L	P	N	T	C	G	H	F	W	E	M	V	W	E	Q
Template Known Secondary structure		G	G	G					S		S	S	.	.	.	.	.												T	.	.	.	.	.	T	T	T											T	T	T											T
Template Predicted Secondary structure													.	.	.	.	.													.	.	.	.	.
Template SS confidence
		53	.	.	.	.	.	.	60	.	.	.						.	.	.	.	.	.	70	.	.	.	.	.						.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.
		343	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.		.	370	.	.	.	.			.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																												.							.	.
Query SS confidence																												.							.	.
Query Sequence		N	T	R	V	I	V	M	T	T	R	E	V	E	K	G	R	N	K	C	V	P	Y	W	P	E	V	.	G	T	Q	R	V	Y	.	.	G	L	Y	S	V	T	N	S	R	E	H	D	T	A	E	Y	K	L	R	T	L	Q	I	S	P
Query Conservation																												.							.	.
Alig confidence																												.							.	.
Template Conservation
Template Sequence		K	S	R	G	V	V	M	L	N	R	V	M	E	K	G	S	L	K	C	A	Q	Y	W	P	Q	K	E	E	K	E	M	I	F	E	D	T	N	L	K	L	T	L	I	S	E	D	I	K	S	Y	Y	T	V	R	Q	L	E	L	E	N
Template Known Secondary structure		T								S		S			T	T				S				S		S	S	T	T	S					G	G	G	T												S	S
Template Predicted Secondary structure
Template SS confidence
		103	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.
		400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	D	N	G	D	L	V	R	E	I	W	H	Y	Q	Y	L	S	W	P	D	H	G	V	P	S	E	P	G	G	V	L	S	F	L	D	Q	I	N	Q	R	Q	E	S	L	P	H	A	G	P	I	I	V	H	C	S	A	G	I	G	R
Query Conservation
Alig confidence		.
Template Conservation		.
Template Sequence		.	L	T	T	Q	E	T	R	E	I	L	H	F	H	Y	T	T	W	P	D	F	G	V	P	E	S	P	A	S	F	L	N	F	L	F	K	V	R	E	S	G	S	L	S	P	E	H	G	P	V	V	V	H	C	S	A	G	I	G	R
Template Known Secondary structure		.	T	T	T																T	T				S															T	T	T	T		T	T	S								S	S	S	S	S
Template Predicted Secondary structure		.
Template SS confidence
			163	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.
		460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	G	T	I	I	V	I	D	M	L	M	E	S	I	S	T	K	G	L	D	C	D	I	D	I	Q	K	T	I	Q	M	V	R	A	Q	R	S	G	M	V	Q	T	E	A	Q	Y	K	F	I	Y	V	A	I	A	Q	F	I	E	T	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	G	T	F	C	L	A	D	T	C	L	L	L	M	D	K	R	K	D	P	S	S	V	D	I	K	K	V	L	L	E	M	R	K	F	R	M	G	L	I	Q	T	A	D	Q	L	R	F	S	Y	L	A	V	I	E	G	A	K	F	I
Template Known Secondary structure																		S	S		G	G	G											T	T	T	S	T	T		S		S
Template Predicted Secondary structure
Template SS confidence
		222	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.
		520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	K	K	L	E	I	I	Q	S	Q	K	G	Q	E	S	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	G	D	S	S	V	Q	D	Q	W	K	E	L	S	H	E
Template Known Secondary structure		T	T		S	S										T	T
Template Predicted Secondary structure
Template SS confidence
		282	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D