|   |   |
217 | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | V | N | A | A | D | I | E | N | R | V | L | E | L | N | K | K | Q | E | S | E | D | T | A | K | A | G | F | W | E | E | F | E | S | L | Q | K | Q | E | V | K | N | L | H | Q | R | L | E | G | Q | R | P | E | N | K | S | K | N | R | Y |
| Query Conservation |   |
  |
|   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
| Template Sequence |   |
D | I | S | T | G | H | M | I | L | S | Y | M | E | D | H | . |
. |
. |
. |
. |
. |
L | K | N | K | N | R | L | E | K | E | W | E | A | L | C | A | Y | Q | A | E | P | N | . |
S | S | F | V | A | Q | R | E | E | N | V | P | K | N | R | S |
| Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| S | S |
| . |
|
| T | T | T | T | S | T | T | T | G | G | G |
| S |
|
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . |
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
724 | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | |
. | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . |
|   |
|   |   |
277 | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | N | I | L | P | F | D | H | S | R | V | I | L | Q | G | R | D | S | N | I | P | G | S | D | Y | I | N | A | N | Y | V | K | N | Q | L | L | G | P | D | E | N | S | K | T | Y | I | A | S | Q | G | C | L | D | A | T | V | N | D | F | W |
| Query Conservation |   |
  |
|
|   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|
|   |   |
|
|   |
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |   | . |   |   |
|
|   |
|
|   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |
|   |
|
|   |
|
|   |   |
|
|   |
|
|
|
| Template Sequence |   |
L | A | V | L | T | Y | D | H | S | R | V | L | L | K | A | E | N | S | H | S | H | . |
S | D | Y | I | N | A | S | P | I | M | D | H | . |
. |
. |
. |
D | P | R | N | P | A | Y | I | A | T | Q | G | P | L | P | A | T | V | A | D | F | W |
| Template Known Secondary structure |   |
T | T |
|
|
|
| G | G | G |
|
| B |
|
| T | T | T |
| S | S | S | . |
|
| B |
| S |  |  |  |  |
| S | S | . | . | . | . |
| S | S | S |
| S |  |  |  |  |
|
|
|
| G | G | G |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
| . |
|
|  |  |  |  |  |  |
|
|
|
| . | . | . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
777 | . | . | 780 | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | |
. | . | 800 | . | . | . | . | . | . | . | . | . | |
|
|
|
810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . |
|   |
|   |   |
337 | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | |
. | . | . | . | 390 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  | . |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Q | M | A | W | Q | E | N | T | R | V | I | V | M | T | T | R | E | V | E | K | G | R | N | K | C | V | P | Y | W | P | E | V | G | T | Q | R | V | Y | G | L | Y | S | V | T | N | S | R | E | H | . |
D | T | A | E | Y | K | L | R | T | L |
| Query Conservation |   |
  |
|
|
|
|   |   |   |   |   |
|
|
|
|
|   |   |   |
|   |   |   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   | . |   |   |   |   |   |   |   |
|   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|   |
|   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |   |   |   |   |
|   |   |
|
|
|   |   |   | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
Q | M | V | W | E | S | G | C | V | V | I | V | M | L | T | P | L | A | E | N | G | V | R | Q | C | Y | H | Y | W | P | D | E | G | . |
S | N | L | Y | H | I | Y | E | V | N | L | V | S | E | H | I | W | C | E | D | F | L | V | R | S | F |
| Template Known Secondary structure |   |
 |  |  |  |  | T | T |
|
|  |  |  |  |
| S |
| S |  |  | T | T |  |  |
| S |
|
|
| S |
| S | S | S | . |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
832 | . | . | . | . | . | . | . | 840 | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | . | . | . | 860 | . | . | . | . | |
. | . | . | . | . | 870 | . | . | . | . | . | . | . | . | . | 880 | . | . | . | . | . | . | . | . | . | 890 |
|   |
|   |   |
396 | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Q | I | S | P | L | D | N | G | D | L | V | R | E | I | W | H | Y | Q | Y | L | S | W | P | D | H | G | V | P | S | E | P | G | G | V | L | S | F | L | D | Q | I | N | Q | R | Q | E | S | L | P | H | A | G | P | I | I | V | H | C | S | A |
| Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
| Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   | . | . |   |   |   |
|
|
|
|
|
|   |   |
| Template Sequence |   |
Y | L | K | N | . |
L | Q | T | N | E | T | R | T | V | T | Q | F | H | F | L | S | W | Y | D | R | G | V | P | S | S | S | R | S | L | L | D | F | R | R | K | V | N | K | C | Y | R | G | . |
. |
R | S | C | P | I | I | V | H | C | S | D |
| Template Known Secondary structure |   |
 |  |  |  | . | T | T | T | T |  |  |  |  |  |  |  |  |  |  |
| S |
|
| T | T | S |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S | . | . |
| S | S |
|  |  |  |  |
| S | S |
| Template Predicted Secondary structure |   |
 |  |  |  | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|
|  |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
891 | . | . | . | |
. | . | . | . | . | 900 | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | . | . | . | 920 | . | . | . | . | . | . | . | . | . | 930 | . | . | . | . | . | . | |
|
. | . | . | 940 | . | . | . | . | . | . | . |
|   |
|   |   |
456 | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | I | G | R | T | G | T | I | I | V | I | D | M | L | M | E | S | I | S | T | K | G | L | D | C | D | I | D | I | Q | K | T | I | Q | M | V | R | A | Q | R | S | G | M | V | Q | T | E | A | Q | Y | K | F | I | Y | V | A | I | A | Q | F |
| Query Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|   |   |
|
|   |
|
|   |   |
|
|
|
|   |   |
|
|   |
|
|
|   |
|
|   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |
|   |   |   |   | . | . | . |   |
|
|
|   |   |   |
|   |   |
|
|   |
|
|   |   |   |
|   |
|   |   |
|
|   |
|
|
|   |   |
|   |   |
|
| Template Sequence |   |
G | A | G | R | S | G | T | Y | V | L | I | D | M | V | L | N | K | M | A | K | G | K | . |
. |
. |
E | I | D | I | A | A | T | L | E | H | L | R | D | Q | R | P | G | M | V | Q | T | K | E | Q | F | E | F | A | L | T | A | V | A | E | E |
| Template Known Secondary structure |   |
S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  | T | T | S | T | T | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
948 | . | 950 | . | . | . | . | . | . | . | . | . | 960 | . | . | . | . | . | . | . | . | . | |
|
|
970 | . | . | . | . | . | . | . | . | . | 980 | . | . | . | . | . | . | . | . | . | 990 | . | . | . | . | . | . | . | . | . | 1000 | . | . | . | . |
|   |
|   |   |
516 | . | . | . | 520 | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
| Query Sequence |   |
I | E | T | T | K | K |
| Query Conservation |   |
|   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |   |
| Template Sequence |   |
V | N | A | I | L | A |
| Template Known Secondary structure |   |
 |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|   |   |
1006 | . | . | . | 1010 | . |
|   |