|   |   |
246 | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | E | F | E | S | L | Q | K | Q | E | V | K | N | L | H | Q | R | L | E | G | Q | R | P | E | N | K | S | K | N | R | Y | K | N | I | L | P | F | D | H | S | R | V | I | L | Q | G | R | D | S | N | I | P | G | S | D | Y | I | N | A | N |
| Query Conservation |   |
  |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|   |
|
|   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|   |   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |
|
|   |
|   |   |   | . | . | . | . | . | . |   |
|
|
|
|
|
|
| Template Sequence |   |
I | Q | F | E | Q | L | Y | R | K | K | P | G | L | . |
. |
A | I | T | F | A | K | L | P | Q | N | L | D | K | N | R | Y | K | D | V | L | P | Y | D | T | T | R | V | L | L | Q | G | N | . |
. |
. |
. |
. |
. |
E | D | Y | I | N | A | S |
| Template Known Secondary structure |   |
T |  |  |  |  | S |
| S | S |
| T | T |
| . | . |
|
|
| G | G | G | S | G | G | G | G | G | G |
| S | S | T | T |
|
|
|
| T | T | T |  |  |  |
| S | S | S | . | . | . | . | . | . |
|
|  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
| . | . |
|
|
|  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
| . | . | . | . | . | . |
|
|
|  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
648 | . | 650 | . | . | . | . | . | . | . | . | . | 660 | |
|
. | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . |
|   |
|   |   |
306 | . | . | |
|
|
|
. | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . |
| Predicted Secondary structure |   |
 |
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | V | K | . |
. |
. |
. |
N | Q | L | L | G | P | D | E | N | S | K | T | Y | I | A | S | Q | G | C | L | D | A | T | V | N | D | F | W | Q | M | A | W | Q | E | N | T | R | V | I | V | M | T | T | R | E | V | E | K | G | R | N | K | C |
| Query Conservation |   |
  |
|   | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|
|   |   |
|
|   |
|
|
|   |
|
|
|
|   |   |   |   |   |
|
|
|
|
|   |   |   |
|   |   |   |   |
|
|
| Alig confidence |   |
|
|
| . | . | . | . |
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |   |   |
|   | . | . | . | . | . |   |   |   |   |   |
|
|   |
|
|   |
|   |   |   |
|   |   |
|
|
|   |
|
|   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |
|   |   |   |   |   |
|
| Template Sequence |   |
Y | V | N | M | E | I | P | A | A | . |
. |
. |
. |
. |
N | L | V | N | K | Y | I | A | T | Q | G | P | L | P | H | T | C | A | Q | F | W | Q | V | V | W | D | Q | K | L | S | L | I | V | M | L | T | T | L | T | E | R | G | R | T | K | C |
| Template Known Secondary structure |   |
 |  |  |  |  |  | G | G | G | . | . | . | . | . | T |  |  |  |  |  |  |  |  |
|
|
|
| T | T | T |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
| S |
| S |  |  | T | T |  |  |
|
|
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
700 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . |
|   |
|   |   |
362 | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | P | Y | W | P | E | V | G | T | Q | R | V | Y | G | L | Y | S | V | T | N | S | R | E | H | D | T | A | E | Y | K | L | R | T | L | Q | I | S | P | L | D | N | G | D | L | V | R | E | I | W | H | Y | Q | Y | L | S | W | P | D | H | G |
| Query Conservation |   |
  |   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|   |   |
|
|
|   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   | . |   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |   |
| Template Sequence |   |
H | Q | Y | W | P | D | P | P | D | V | M | N | H | G | G | F | H | I | Q | C | Q | S | E | D | C | T | I | A | Y | V | S | R | E | M | L | V | T | N | T | Q | T | G | E | . |
E | H | T | V | T | H | L | Q | Y | V | A | W | P | D | H | G |
| Template Known Secondary structure |   |
|
|
| S |
|
| T | T |
|  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
| . |  |  |  |  |  |  |  |  |  |
|
| S |
| S | S | S |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
755 | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | |
. | . | 800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . |
|   |
|   |   |
422 | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . |
| Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | P | S | E | P | G | G | V | L | S | F | L | D | Q | I | N | Q | R | Q | E | S | L | P | H | A | G | P | I | I | V | H | C | S | A | G | I | G | R | T | G | T | I | I | V | I | D | M | L | M | E | S | I | S | T | K | G | L | D | C | D |
| Query Conservation |   |
|
|   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
| Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . | . | . |   |   |   |
|
|
|
|
|
|   |   |
|   |
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |
|   |   |   |   | . | . | . |   |
| Template Sequence |   |
V | P | D | D | S | S | D | F | L | E | F | V | N | Y | V | R | S | L | R | V | . |
. |
. |
D | S | E | P | V | L | V | H | C | S | A | G | I | G | R | T | G | V | L | V | T | M | E | T | A | M | C | L | T | E | R | N | L | . |
. |
. |
P |
| Template Known Secondary structure |   |
|
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | T | T |
|
|  |  |  |  |
| S | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . | . | . |
|
| Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
814 | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | |
|
|
. | . | . | . | . | . | 840 | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | . | . | . | 860 | . | . | . | . | . | . | |
|
|
. |
|   |
|   |   |
482 | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
I | D | I | Q | K | T | I | Q | M | V | R | A | Q | R | S | G | M | V | Q | T | E | A | Q | Y | K | F | I | Y | V | A | I | A | Q | F | I | E |
| Query Conservation |   |
|
|
|   |   |   |
|   |   |
|
|   |
|
|   |   |
|
|
|
|   |   |
|
|   |
|
|
|   |
|
|   |   |
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |
|   |   |   |
|   |   |
|
|   |
|
|   |   |   |
|   |
|   |   |
|
|   |
|
|
|   |   |
|
|   |   |
|   |
| Template Sequence |   |
I | Y | P | L | D | I | V | R | K | M | R | D | Q | R | A | M | M | V | Q | T | S | S | Q | Y | K | F | V | C | E | A | I | L | R | V | Y | E |
| Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  | T | T | S | T | T |
| S |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
868 | . | 870 | . | . | . | . | . | . | . | . | . | 880 | . | . | . | . | . | . | . | . | . | 890 | . | . | . | . | . | . | . | . | . | 900 | . | . | . |
|   |