Job Description Q60992 Confidence 100.00% Date Wed Jul 10 14:34:39 BST 2013 Rank 2 Aligned Residues 366 % Identity 55% Template c2vrwB_ PDB info PDB header:signaling protein Chain: B: PDB Molecule:proto-oncogene vav; PDBTitle: critical structural role for the ph and c1 domains of the2 vav1 exchange factor Resolution 1.85 Å Model Dimensions (Å) X:90.160 Y:72.204 Z:54.266

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		189	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	E	D	D	K	R	S	C	C	L	L	E	I	Q	E	T	E	A	K	Y	Y	R	T	L	E	D	I	E	K	N	Y	M	G	P	L	R	L	V	L	S	P	A	D	M	A	A	V	F	I	N	L	E	D	L	I	K	V	H	H	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		T	E	Y	D	K	R	C	C	C	L	R	E	I	Q	Q	T	E	E	K	Y	T	D	T	L	G	S	I	Q	Q	H	F	M	K	P	L	Q	R	F	L	K	P	Q	D	M	E	T	I	F	V	N	I	E	E	L	F	S	V	H	T	H
Template Known Secondary structure																																T					T	T	T	S										T	T
Template Predicted Secondary structure
Template SS confidence
		190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.
		249	250	.	.	.	.	.	.	.	.	.	260	.		.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.
Predicted Secondary structure															.
Query SS confidence															.
Query Sequence		F	L	R	A	I	D	V	S	M	M	A	G	G	.	S	T	L	A	K	V	F	L	E	F	K	E	R	L	L	I	Y	G	E	Y	C	S	H	M	E	H	A	Q	S	T	L	N	Q	L	L	A	S	R	E	D	F	R	Q	K	V	E
Query Conservation															.
Alig confidence															.
Template Conservation
Template Sequence		F	L	K	E	L	K	D	A	L	A	G	P	G	A	T	T	L	Y	Q	V	F	I	K	Y	K	E	R	F	L	V	Y	G	R	Y	C	S	Q	V	E	S	A	S	K	H	L	D	Q	V	A	T	A	R	E	D	V	Q	M	K	L	E
Template Known Secondary structure												S	G	G	G	T	T									T	T	G	G	G
Template Predicted Secondary structure
Template SS confidence
		250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.
		308	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	C	T	L	R	V	Q	D	G	K	F	K	L	Q	D	L	L	V	V	P	M	Q	R	V	L	K	Y	H	L	L	L	K	E	L	L	S	H	S	A	D	R	P	E	R	Q	Q	L	K	E	A	L	E	A	M	Q	D	L	A	M	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	C	S	Q	R	A	N	N	G	R	F	T	L	R	D	L	L	M	V	P	M	Q	R	V	L	K	Y	H	L	L	L	Q	E	L	V	K	H	T	Q	D	A	T	E	K	E	N	L	R	L	A	L	D	A	M	R	D	L	A	Q	C
Template Known Secondary structure									T	T	S							T	T							T	T
Template Predicted Secondary structure
Template SS confidence
		310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.
		368	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	N	E	V	K	R	D	K	E	T	L	K	K	I	S	E	F	Q	C	S	I	E	N	L	Q	V	K	L	E	E	F	G	R	P	K	I	D	G	E	L	K	V	R	S	I	V	N	H	T	K	Q	D	R	Y	L	F	L	F	D	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	N	E	V	K	R	D	N	E	T	L	R	Q	I	T	N	F	Q	L	S	I	E	N	L	D	Q	S	L	A	N	Y	G	R	P	K	I	D	G	E	L	K	I	T	S	V	E	R	R	S	K	T	D	R	Y	A	F	L	L	D	K
Template Known Secondary structure																								S		S	S		G	G	G	G		S												S	S			S										S	S
Template Predicted Secondary structure
Template SS confidence
		370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.
		428	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	V	I	V	C	K	R	K	G	Y	S	Y	E	L	K	E	V	I	E	L	L	F	H	K	M	T	D	D	P	M	H	N	K	D	I	K	K	W	S	Y	G	F	Y	L	I	H	L	Q	G	K	Q	G	F	Q	F	F	C	K	T	E
Query Conservation
Alig confidence																														.	.	.	.	.	.	.	.
Template Conservation																														.	.	.	.	.	.	.	.
Template Sequence		A	L	L	I	C	K	R	R	G	D	S	Y	D	L	K	A	S	V	N	L	H	S	F	Q	V	R	D	K	.	.	.	.	.	.	.	.	K	W	S	H	M	F	L	L	I	E	D	Q	G	A	Q	G	Y	E	L	F	F	K	T	R
Template Known Secondary structure										T	T										T	T	T							.	.	.	.	.	.	.	.	T	T									T	T		S								S	S
Template Predicted Secondary structure																														.	.	.	.	.	.	.	.
Template SS confidence
		430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.									.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.
		488	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	M	K	R	K	W	M	E	Q	F	E	M	A	M	S	N	I	K	P	D	K	A	N	A	N	H	H	S	F	Q	M	Y	T	F	D	K	T	T	N	C	K	A	C	K	M	F	L	R	G	T	F	Y	Q	G	Y	L	C	T	R	C
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	L	K	K	K	W	M	E	Q	F	E	M	A	I	S	N	I	Y	P	E	N	A	T	A	N	G	H	D	F	Q	M	F	S	F	E	E	T	T	S	C	K	A	C	Q	M	L	L	R	G	T	F	Y	Q	G	Y	R	C	Y	R	C
Template Known Secondary structure																			S		T	T	T	T	G	G	G									S	S			B		T	T	T			B			S	S	S	S						T	T	T
Template Predicted Secondary structure
Template SS confidence
		490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.
		548	.	550	.	.	.	.	.	.	.	.	.	560	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	V	G	A	H	K	E	C	L	E	V	I	P	P	C
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	A	P	A	H	K	E	C	L	G	R	V	P	P	C
Template Known Secondary structure							G	G	G	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		550	.	.	.	.	.	.	.	.	.	560	.	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D