Job Description Q60992 Confidence 100.00% Date Wed Jul 10 14:34:39 BST 2013 Rank 6 Aligned Residues 299 % Identity 21% Template c1xdvB_ PDB info PDB header:signaling protein Chain: B: PDB Molecule:son of sevenless protein homolog 1; PDBTitle: experimentally phased structure of human the son of2 sevenless protein at 4.1 ang. Resolution 4.10 Å Model Dimensions (Å) X:57.352 Y:81.844 Z:46.661

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		194	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.				.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250
Predicted Secondary structure																																		.	.	.
Query SS confidence																																		.	.	.
Query Sequence		R	S	C	C	L	L	E	I	Q	E	T	E	A	K	Y	Y	R	T	L	E	D	I	E	K	N	Y	M	G	P	L	R	L	.	.	.	V	L	S	P	A	D	M	A	A	V	F	I	N	L	E	D	L	I	K	V	H	H	S	F	L
Query Conservation																																		.	.	.
Alig confidence																																		.	.	.
Template Conservation
Template Sequence		Y	Y	D	L	V	K	A	F	M	A	E	I	R	Q	Y	I	R	E	L	N	L	I	I	K	V	F	R	E	P	F	V	S	N	S	K	L	F	S	A	N	D	V	E	N	I	F	S	R	I	V	D	I	H	E	L	S	V	K	L	L
Template Known Secondary structure																										T	T	T							T	T	T											T	T
Template Predicted Secondary structure
Template SS confidence
		201	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260
		251	.	.	.	.	.	.	.						.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.			.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290			.	.	.	.	.	.	.	.	.	300	.
Predicted Secondary structure										.	.	.	.	.																	.	.																	.	.
Query SS confidence										.	.	.	.	.																	.	.																	.	.
Query Sequence		R	A	I	D	V	S	M	M	.	.	.	.	.	A	G	G	S	T	L	A	K	V	F	L	E	F	K	E	R	.	.	L	L	I	Y	G	E	Y	C	S	H	M	E	H	A	Q	S	.	.	T	L	N	Q	L	L	A	S	R	E	D
Query Conservation										.	.	.	.	.																	.	.																	.	.
Alig confidence										.	.	.	.	.																	.	.																	.	.
Template Conservation
Template Sequence		G	H	I	E	D	T	V	E	M	T	D	E	G	S	P	H	P	L	V	G	S	C	F	E	D	L	A	E	E	L	A	F	D	P	Y	E	S	Y	A	R	D	I	L	R	P	G	F	H	D	R	F	L	S	Q	L	S	K	P	G	A
Template Known Secondary structure										T			T	T	S	S	S													T	T	T	T											T	S	T	T											S	T	T
Template Predicted Secondary structure
Template SS confidence
		261	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320
		302	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	R	Q	K	V	E	E	C	T	L	R	V	Q	D	G	K	F	K	L	Q	D	L	L	V	V	P	M	Q	R	V	L	K	Y	H	L	L	L	K	E	L	L	S	H	S	A	D	R	P	E	R	Q	Q	L	K	E	A	L	E	A	M
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	L	Y	L	Q	S	I	G	E	G	F	K	E	A	V	Q	Y	V	L	P	R	L	L	L	A	P	V	Y	H	C	L	H	Y	F	E	L	L	K	Q	L	E	E	K	S	E	D	Q	E	D	K	E	C	L	K	Q	A	I	T	A	L
Template Known Secondary structure										T	T								T					T	T																					S															T
Template Predicted Secondary structure
Template SS confidence
		321	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380
		362	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.									.	380	.	.	.	.	.	.	.	.	.	390	.	.	.			.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.
Predicted Secondary structure																			.	.	.	.	.	.	.	.																.	.
Query SS confidence																			.	.	.	.	.	.	.	.																.	.
Query Sequence		Q	D	L	A	M	Y	I	N	E	V	K	R	D	K	E	T	L	.	.	.	.	.	.	.	.	K	K	I	S	E	F	Q	C	S	I	E	N	L	Q	V	.	.	K	L	E	E	F	G	R	P	K	I	D	G	E	L	K	V	R	S
Query Conservation																			.	.	.	.	.	.	.	.																.	.
Alig confidence																			.	.	.	.	.	.	.	.																.	.																.	.	.
Template Conservation																																																											.	.	.
Template Sequence		L	N	V	Q	S	G	M	E	K	I	C	S	K	S	L	A	K	R	R	L	S	E	S	A	I	K	K	M	N	E	I	Q	K	N	I	D	G	W	E	G	K	D	I	G	Q	C	C	N	E	F	I	M	E	G	T	L	T	.	.	.
Template Known Secondary structure														S										T										T	T			S			S	S		G	G	G	T												.	.	.
Template Predicted Secondary structure																																																											.	.	.
Template SS confidence
		381	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.
		412	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	V	N	H	T	K	Q	D	R	Y	L	F	L	F	D	K	V	V	I	V	C	K	R	K	G	Y	S	Y	E	L	K	E	V	I	E	L	L	F	H	K	M	T	D	D	P	M	H	N	K	D	I	K	K	W	S	Y	G	F	Y	L
Query Conservation
Alig confidence		.																									.	.																			.	.	.	.
Template Conservation		.																									.	.																			.	.	.	.
Template Sequence		.	R	V	G	A	K	H	E	R	H	I	F	L	F	D	G	L	M	I	C	C	K	S	N	E	.	.	Y	R	L	K	E	K	F	F	M	R	K	V	Q	I	N	D	K	D	.	.	.	.	D	T	N	E	Y	K	H	A	F	E	I
Template Known Secondary structure		.		T	T		S	S								S	S										.	.									S		S								.	.	.	.		S	S	S			S
Template Predicted Secondary structure		.																									.	.																			.	.	.	.
Template SS confidence
			452	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.			.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.					.	.	.	.	.	.	500	.	.	.	.
		472	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	H	L	Q	G	K	Q	G	F	Q	F	F	C	K	T	E	D	M	K	R	K	W	M	E	Q	F	E	M	A	M	S	N
Query Conservation
Alig confidence							.
Template Conservation							.
Template Sequence		I	L	K	D	E	.	N	S	V	I	F	S	A	K	S	A	E	E	K	N	N	W	M	A	A	L	I	S	L	Q	Y	R
Template Known Secondary structure				T	T	S	.								S	S																T	T
Template Predicted Secondary structure							.
Template SS confidence
		517	.	.	520	.		.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D