Job Description Q60992 Confidence 100.00% Date Wed Jul 10 14:34:39 BST 2013 Rank 9 Aligned Residues 315 % Identity 19% Template c1x86A_ PDB info PDB header:signaling protein/membrane protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 12; PDBTitle: crystal structure of the dh/ph domains of leukemia-associated rhogef2 in complex with rhoa Resolution 3.22 Å Model Dimensions (Å) X:77.077 Y:70.108 Z:46.607

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		188	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.			.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.
Predicted Secondary structure																																								.	.
Query SS confidence																																								.	.
Query Sequence		M	T	E	D	D	K	R	S	C	C	L	L	E	I	Q	E	T	E	A	K	Y	Y	R	T	L	E	D	I	E	K	N	Y	M	G	P	L	R	L	.	.	V	L	S	P	A	D	M	A	A	V	F	I	N	L	E	D	L	I	K	V
Query Conservation																																								.	.
Alig confidence																																								.	.
Template Conservation
Template Sequence		K	P	C	E	I	K	R	Q	E	V	I	N	E	L	F	Y	T	E	R	A	H	V	R	T	L	K	V	L	D	Q	V	F	Y	Q	R	V	S	R	E	G	I	L	S	P	S	E	L	R	K	I	F	S	N	L	E	D	I	L	Q	L
Template Known Secondary structure			T	T																													T								S		S										T	T
Template Predicted Secondary structure
Template SS confidence
		782	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.
		246	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.					.	.	.	.	.	.	.	.	270	.	.							.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.
Predicted Secondary structure																		.	.	.	.												.	.	.	.	.	.
Query SS confidence																		.	.	.	.												.	.	.	.	.	.
Query Sequence		H	H	S	F	L	R	A	I	D	V	S	M	M	A	G	G	.	.	.	.	S	T	L	A	K	V	F	L	E	F	K	.	.	.	.	.	.	E	R	L	L	I	Y	G	E	Y	C	S	H	M	E	H	A	Q	S	T	L	N	Q	L
Query Conservation																		.	.	.	.												.	.	.	.	.	.
Alig confidence																		.	.	.	.												.	.	.	.	.	.
Template Conservation
Template Sequence		H	I	G	L	N	E	Q	M	K	A	V	R	K	R	N	E	T	S	V	I	D	Q	I	G	E	D	L	L	T	W	F	S	G	P	G	E	E	K	L	K	H	A	A	A	T	F	C	S	N	Q	P	F	A	L	E	M	I	K	S	R
Template Known Secondary structure																	S	S	S	S													S																	T
Template Predicted Secondary structure
Template SS confidence
		842	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.
		296	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	A	S	R	E	D	F	R	Q	K	V	E	E	C	T	L	R	V	Q	D	G	K	F	K	L	Q	D	L	L	V	V	P	M	Q	R	V	L	K	Y	H	L	L	L	K	E	L	L	S	H	S	A	D	R	P	E	R	Q	Q	L	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Q	K	K	D	S	R	F	Q	T	F	V	Q	D	A	E	S	N	P	L	C	R	R	L	Q	L	K	D	I	I	P	T	Q	M	Q	R	L	T	K	Y	P	L	L	L	D	N	I	A	K	Y	T	E	W	P	T	E	R	E	K	V	K
Template Known Secondary structure																	T	S	G	G	G	T	T							T	T																			T
Template Predicted Secondary structure
Template SS confidence
		902	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.
		356	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.														.	.	400	.	.
Predicted Secondary structure																																												.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																												.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		E	A	L	E	A	M	Q	D	L	A	M	Y	I	N	E	V	K	R	D	K	E	T	L	K	K	I	S	E	F	Q	C	S	I	E	N	L	Q	V	K	L	E	E	.	.	.	.	.	.	.	.	.	.	.	.	.	F	G	R	P	K
Query Conservation																																												.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																												.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		K	A	A	D	H	C	R	Q	I	L	N	F	V	N	Q	A	V	K	E	A	E	N	K	Q	R	L	E	D	Y	Q	R	R	L	D	T	S	S	L	K	L	S	E	Y	P	N	V	E	E	L	R	N	L	D	L	T	K	R	K	M	I
Template Known Secondary structure																																	T				S	S			S	S	S		G	G	G					S			G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		962	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.
		403	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.							.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.
Predicted Secondary structure																																						.	.	.	.	.	.
Query SS confidence																																						.	.	.	.	.	.
Query Sequence		I	D	G	E	L	K	V	R	S	I	V	N	H	T	K	Q	D	R	Y	L	F	L	F	D	K	V	V	I	V	C	K	R	K	G	Y	S	.	.	.	.	.	.	Y	E	L	K	E	V	I	E	L	L	F	H	K	M	T	D	D	P
Query Conservation																																						.	.	.	.	.	.
Alig confidence								.																														.	.	.	.	.	.																		.
Template Conservation								.																																																					.
Template Sequence		H	E	G	P	L	V	.	W	K	V	N	R	D	K	T	I	D	L	Y	T	L	L	L	E	D	I	L	V	L	L	Q	K	Q	D	D	R	L	V	L	R	C	H	S	T	F	S	P	V	I	K	L	S	T	V	L	V	R	Q	V	.
Template Known Secondary structure								.			S		T	T											S	S							B		S	S												S				T	T	S							.
Template Predicted Secondary structure								.																																																					.
Template SS confidence
		1022	.	.	.	.	.		.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.
		457	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	H	N	K	D	I	K	K	W	S	Y	G	F	Y	L	I	H	L	Q	G	K	Q	G	F	Q	F	F	C	K	T	E	D	M	K	R	K	W	M	E	Q	F	E	M	A	M	S	N	I	K	P	D	K
Query Conservation
Alig confidence		.	.	.	.
Template Conservation		.	.	.	.
Template Sequence		.	.	.	.	A	T	D	N	K	A	L	F	V	I	S	M	S	D	N	G	A	Q	I	Y	E	L	V	A	Q	T	V	S	E	K	T	V	W	Q	D	L	I	C	R	M	A	A	S	V	K	E	Q	S
Template Known Secondary structure		.	.	.	.	S	S	S	T	T							B		S	S		B								S	S																				T
Template Predicted Secondary structure		.	.	.	.
Template SS confidence
						1091	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D