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Job DescriptionQ6TXD4
Confidence100.00%DateTue Jul 30 13:06:16 BST 2013
Rank1Aligned Residues264
% Identity41%Templatec2dx1A_
PDB info PDB header:signaling proteinChain: A: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crystal structure of rhogef protein asef
Resolution2.36 Å
Model Dimensions (Å)X:56.922 Y:64.174 Z:42.291

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   244.....250.........260.........270.........280.........290.........300...
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Query Sequence  QSGTYGIALYRFQALETNELDFEVGDRIQILGTLEDGWLEGCLKGKTGVFPHRFVKLCPS
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Template Sequence  GSVVCAEALWDHVTXDDQELGFKAGDVIEVXDATNREWWWGRVADGEGWFPASFVRLRVN
Template Known Secondary structure  T

SS
B



TTB

B
TT


SSS
SS
GGG
S
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   123......130.........140.........150.........160.........170.........180..
 
   304.....310.........320.........330.........340.........350.........360...
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Query Sequence  NRTEETTAQPQESSFPKDSESSVGKSGDSVVEEARQEPWECEEERPDYDLPGQASVPQDH
Query Conservation           
                                                  
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Template Conservation     .........................................................
Template Sequence  QDA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   183..
 
   364.....370.........380.........390.........400.........410.........420...
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Query Sequence  VAPEWTGDTISGQDKDASGSSPDVDLERPLAKDLSTPDPSEEVNGVSSQPQVPIHPKVQK
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   424.....430.........440.........450.........460.........470.........480...
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Query Sequence  SQHYLTAGGSHQTSDPFSELVPLEARTRDYSSLPPRRTYAQGWSFQKPASHLQRASSLTA
Query Conservation                                                              
Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   484.....490.........500.........510.........520.........530.........540...
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Query Sequence  SRLDRPSHFCHPAMASYAQKHQTSTENTASLHDPPERPERRPGLQDRGPATDITTASQGD
Query Conservation 
                                                           
Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   544.....550.........560.........570.........580.........590.........600...
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Query Sequence  SLDLDSKLTQQLIEFEKSLSGPSTEPETIVRRFSIMDFYSEKDIVRGSSNSLPSQAFPER
Query Conservation                                   
                          
Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   604.....610.........620.........630.........640.........650.........660...
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Query Sequence  RKTLRPPPPRPRTPTPISSHLLVDQSPKPVPTLVVRPSRPAPLPPPAQQRMNTASPKPTS
Query Conservation                                                             
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   664.....670.........680.........690.........700.........710.........720...
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Query Sequence  CAHPGWEAPEKEDSEHMEKSPAQTFPCPSMLARIRDVEQDLDTCTRAQEELNLLLEEKQD
Query Conservation                                                   

         
Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   724.....730.........740.........750.........760.........770.........780...
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Query Sequence  DPSRAETLETLRSYESTIQSLTLELQQLRDMTLLSSQSSSLAAPFGSVSTENPEQRMLEK
Query Conservation          
      
                                            
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Template Conservation  .....................................................    
  
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . QSSKDQX
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   207..210...
 
   784.....790.........800.........810....... ..820.........830.........840.
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Query Sequence  RAKVVAELLQTERDYIRDLEMCIERVMVPLQQAQ. . VPNVDFEGLFGNMQTVIKVSKQLL
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Template Sequence  RTNVINEILSTERDYIKHLRDICEGYVRQCRKRADXFSEEQLRTIFGNIEDIYRCQKAFV
Template Known Secondary structure  TTT
TTT

TT
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   214.....220.........230.........240.........250.........260.........270...
 
   842.......850.........860.........870.........880.........890.........900.
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Query Sequence  AALEISDAVGMSSCDCLVPGPVFLDHRDELEGTYRVYCQNHDEAISLLEMYEKDEKTQKH
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Template Sequence  KALEQRFNRE. . RPHLSELGACFLEHQADFQ. IYSEYCNNHPNACVELSRLTKLSKYVYF
Template Known Secondary structure  TT

SS..SGGG


T.TT
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   274.....280... ......290.........300.. .......310.........320.........330
 
   902.......910.........920.........930.........940.........950.........960.
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Query Sequence  LQDYLADLKGCTNYINLGSFLIKPVQRIMRYPLLLMELLNSTPESHPDKVPLTNAVLAVK
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Template Sequence  FEAC. . RLLQKXIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAXK
Template Known Secondary structure  ..T

S

TS
TT
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   331... .....340.........350.........360.........370.........380........
 
   962.......970.........980..
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Query Sequence  EINVNINEYKRRKDLVLKYRK
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Template Conservation   
   


  
  
    
  
Template Sequence  NVAQLINERKRRLENIDKIAQ
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   389390.........400.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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