Job Description Q6TXD4 Confidence 99.96% Date Tue Jul 30 13:06:16 BST 2013 Rank 9 Aligned Residues 221 % Identity 18% Template c1x86A_ PDB info PDB header:signaling protein/membrane protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 12; PDBTitle: crystal structure of the dh/ph domains of leukemia-associated rhogef2 in complex with rhoa Resolution 3.22 Å Model Dimensions (Å) X:45.048 Y:66.974 Z:52.647

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		762	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.		.	.	820
Predicted Secondary structure																																																										.
Query SS confidence																																																										.
Query Sequence		S	S	L	A	A	P	F	G	S	V	S	T	E	N	P	E	Q	R	M	L	E	K	R	A	K	V	V	A	E	L	L	Q	T	E	R	D	Y	I	R	D	L	E	M	C	I	E	R	V	M	V	P	L	Q	Q	A	Q	.	V	P	N
Query Conservation																																																										.
Alig confidence																																																										.
Template Conservation
Template Sequence		P	P	N	W	Q	Q	L	V	S	R	E	V	L	L	G	L	K	P	C	E	I	K	R	Q	E	V	I	N	E	L	F	Y	T	E	R	A	H	V	R	T	L	K	V	L	D	Q	V	F	Y	Q	R	V	S	R	E	G	I	L	S	P
Template Known Secondary structure					G	G	G	T	S						T	T	S		T	T																													T								S		S
Template Predicted Secondary structure
Template SS confidence
		766	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.
		821	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.						.	.	870	.	.	.	.	.
Predicted Secondary structure																																																	.	.	.	.	.
Query SS confidence																																																	.	.	.	.	.
Query Sequence		V	D	F	E	G	L	F	G	N	M	Q	T	V	I	K	V	S	K	Q	L	L	A	A	L	E	I	S	D	A	V	G	M	S	S	C	D	C	L	V	P	G	P	V	F	L	D	H	.	.	.	.	.	R	D	E	L	E	G	T	Y
Query Conservation																																																	.	.	.	.	.
Alig confidence																																								.									.	.	.	.	.
Template Conservation																																								.
Template Sequence		S	E	L	R	K	I	F	S	N	L	E	D	I	L	Q	L	H	I	G	L	N	E	Q	M	K	A	V	R	K	R	N	E	T	S	V	I	D	Q	.	I	G	E	D	L	L	T	W	F	S	G	P	G	E	E	K	L	K	H	A	A
Template Known Secondary structure									T	T																							S	S	S	S				.										S
Template Predicted Secondary structure																																								.
Template SS confidence
		826	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.		.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.
		876	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.		.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.
Predicted Secondary structure																			.
Query SS confidence																			.
Query Sequence		R	V	Y	C	Q	N	H	D	E	A	I	S	L	L	E	M	Y	.	E	K	D	E	K	T	Q	K	H	L	Q	D	Y	L	A	D	L	K	G	C	T	N	Y	I	N	L	G	S	F	L	I	K	P	V	Q	R	I	M	R	Y	P	L
Query Conservation																			.
Alig confidence																			.														.	.
Template Conservation																																	.	.
Template Sequence		A	T	F	C	S	N	Q	P	F	A	L	E	M	I	K	S	R	Q	K	K	D	S	R	F	Q	T	F	V	Q	D	A	.	.	E	S	N	P	L	C	R	R	L	Q	L	K	D	I	I	P	T	Q	M	Q	R	L	T	K	Y	P	L
Template Known Secondary structure							T																										.	.		T	S	G	G	G	T	T							T	T
Template Predicted Secondary structure																																	.	.
Template SS confidence
		885	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.			.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.
		935	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	L	M	E	L	L	N	S	T	P	E	S	H	P	D	K	V	P	L	T	N	A	V	L	A	V	K	E	I	N	V	N	I	N	E	Y	K	R	R	K	D	L	V	L	K	Y	R	K	G	D	E	D
Query Conservation
Alig confidence													.
Template Conservation													.
Template Sequence		L	L	D	N	I	A	K	Y	T	E	W	.	P	T	E	R	E	K	V	K	K	A	A	D	H	C	R	Q	I	L	N	F	V	N	Q	A	V	K	E	A	E	N	K	Q	R	L	E	D	Y	Q	R	R
Template Known Secondary structure									T				.																																								T
Template Predicted Secondary structure													.
Template SS confidence
		943	.	.	.	.	.	.	950	.	.	.		.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D