Job Description Q80TT8 Confidence 99.96% Date Wed Jul 10 14:12:26 BST 2013 Rank 4 Aligned Residues 512 % Identity 22% Template c1u6gA_ PDB info PDB header:ligase Chain: A: PDB Molecule:cullin homolog 1; PDBTitle: crystal structure of the cand1-cul1-roc1 complex Resolution 3.10 Å Model Dimensions (Å) X:104.637 Y:92.397 Z:72.248

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		643	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	R	E	Q	L	C	R	R	T	C	L	F	Y	T	I	R	A	Q	A	W	S	R	D	I	A	E	D	R	Q	R	L	L	Q	L	Y	P	R	L	N	R	V	L	R	H	E	Q	N	F	A	D	R	F	L	P	D	D	E	A	A	Q
Query Conservation
Alig confidence																										.	.	.	.	.																									.
Template Conservation																										.	.	.	.	.																									.
Template Sequence		F	E	S	Q	F	L	A	D	T	E	R	F	Y	T	R	E	S	T	E	F	L	Q	Q	N	.	.	.	.	.	P	V	T	E	Y	M	K	K	A	E	A	R	L	L	E	E	Q	R	R	V	Q	V	Y	L	.	H	E	S	T	Q	D
Template Known Secondary structure		T																							S	.	.	.	.	.																						T	T	S	.		G	G	G
Template Predicted Secondary structure																										.	.	.	.	.																									.
Template SS confidence
		231	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.						.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.		.	280	.	.	.	.
		703	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	L	G	K	T	C	W	E	A	L	V	S	P	L	V	Q	N	I	T	S	P	D	A	G	G	V	S	S	L	G	W	L	L	D	Q	Y	L	E	H	R	E	S	T	R	S	R	Q	G	P	A	A	S	F	A	S	Q	V	R	R	L
Query Conservation
Alig confidence																							.	.	.	.	.	.	.	.	.	.	.													.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																							.	.	.	.	.	.	.	.	.	.	.													.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		E	L	A	R	K	C	E	Q	V	L	I	E	K	H	L	E	I	F	H	T	E	.	.	.	.	.	.	.	.	.	.	.	F	Q	N	L	L	D	A	D	K	N	E	D	.	.	.	.	.	.	.	.	.	.	.	.	L	G	R	M
Template Known Secondary structure												T	T	T	S								.	.	.	.	.	.	.	.	.	.	.							S			T	T		.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																							.	.	.	.	.	.	.	.	.	.	.													.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		285	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.												.	.	.	.	310	.	.	.	.	.	.	.													.	.	320	.
		763	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		C	H	L	L	V	H	V	E	A	P	P	G	P	S	P	E	P	S	S	Q	P	L	S	K	N	S	K	G	Q	D	G	S	P	T	P	A	P	T	P	V	C	P	S	T	S	L	R	N	L	T	Q	C	W	L	S	V	V	Q	G	Q
Query Conservation
Alig confidence										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		Y	N	L	V	S	R	I	Q	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	D	G	L	G	E	L	K	K	L	L	E	T	H	I	H	N	Q
Template Known Secondary structure						T	T	S	T	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T	T	T
Template Predicted Secondary structure										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		322	.	.	.	.	.	.	.																																				330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.
		823	.	.	.	.	.	.	830	.	.	.	.						.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.
Predicted Secondary structure														.	.	.	.	.
Query SS confidence														.	.	.	.	.
Query Sequence		V	S	R	F	L	A	A	A	W	R	A	S	.	.	.	.	.	D	F	V	P	R	Y	C	S	L	Y	Q	R	L	Q	S	A	G	S	E	L	F	G	P	R	A	A	F	T	L	A	L	R	S	G	F	S	G	A	L	L	Q	Q	S
Query Conservation														.	.	.	.	.
Alig confidence														.	.	.	.	.
Template Conservation
Template Sequence		G	L	A	A	I	E	K	C	G	E	A	A	L	N	D	P	K	M	Y	V	Q	T	V	L	D	V	H	K	K	Y	N	A	L	V	M	S	A	F	N	N	D	A	G	F	V	A	A	L	D	K	A	C	G	R	F	I	N	N	N	A
Template Known Secondary structure								T	T	T	T																										T	T	T	T	T																		S	S
Template Predicted Secondary structure
Template SS confidence
		347	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.
		878	.	880	.	.					.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.
Predicted Secondary structure							.	.	.	.
Query SS confidence							.	.	.	.
Query Sequence		F	L	T	A	A	.	.	.	.	H	I	S	E	Q	F	A	R	H	I	D	Q	Q	I	H	G	G	L	L	G	G	A	A	G	V	G	M	L	G	R	L	Q	R	H	L	E	P	I	M	V	L	S	G	L	E	L	A	T	T	F	E
Query Conservation							.	.	.	.
Alig confidence							.	.	.	.																				.	.	.	.	.	.	.	.	.
Template Conservation																														.	.	.	.	.	.	.	.	.
Template Sequence		V	T	K	M	A	Q	S	S	S	K	S	P	E	L	L	A	R	Y	C	D	S	L	L	K	K	E	E	A	.	.	.	.	.	.	.	.	.	E	L	E	D	T	L	N	Q	V	M	V	V	F	K	Y	I	E	D	K	D	V	F	Q
Template Known Secondary structure						T	T	S	T	T																				.	.	.	.	.	.	.	.	.																	S
Template Predicted Secondary structure																														.	.	.	.	.	.	.	.	.
Template SS confidence
		407	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.										.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.
		934	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.			950	.	.	.	.	.	.	.	.	.	960					.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.
Predicted Secondary structure																		.	.												.	.	.	.
Query SS confidence																		.	.												.	.	.	.
Query Sequence		H	F	Y	Q	H	Y	M	A	D	R	L	L	S	L	G	S	.	.	S	W	L	E	G	A	V	L	E	Q	I	.	.	.	.	G	P	C	F	P	N	R	L	P	Q	L	M	L	Q	S	L	H	T	S	E	E	L	Q	H	R	F	H
Query Conservation																		.	.												.	.	.	.
Alig confidence																		.	.												.	.	.	.									.
Template Conservation																																											.
Template Sequence		K	F	Y	A	K	M	L	A	K	R	L	V	H	Q	N	S	A	S	D	D	A	E	A	S	M	I	S	K	L	K	Q	A	C	G	F	E	Y	T	S	K	L	.	Q	R	M	F	Q	D	I	G	V	S	K	D	L	N	E	Q	F	K
Template Known Secondary structure														S	S																			S		S							.
Template Predicted Secondary structure																																											.
Template SS confidence
		463	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.		.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.
		988	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	F	Q	L	Q	Q	L	D	R	Q	L	L	E	Q	G	D	Q	E	E	W	R	P	E	K	V	E	E	D	D	E	G	Q	E	T	G	R	E	L	F	T	D	P	G	P	A	I	S	V	L	V	L	S	P	R	C	W	P	V	S	P
Query Conservation
Alig confidence								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		K	H	L	T	N	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	P	L	D	L	D	F	S	I	Q	V	L	S	S	G	S	W	P	F	Q	Q
Template Known Secondary structure						T	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.				S	S									G	G	G
Template Predicted Secondary structure								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		522	.	.	.	.	.																																		.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.
		1048	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.		.	.	.	.	.	.	.	1100	.	.
Predicted Secondary structure																																															.											.	.	.	.
Query SS confidence																																															.											.	.	.	.
Query Sequence		L	C	Y	L	H	H	P	R	K	H	L	Q	A	E	L	C	D	A	L	E	R	F	S	S	F	Y	S	H	S	Q	N	C	P	V	L	D	I	G	P	H	R	R	L	Q	W	.	T	W	L	G	R	A	E	L	Q	L	.	.	.	.
Query Conservation																																															.											.	.	.	.
Alig confidence							.	.	.	.	.																						.	.	.	.	.	.	.	.							.											.	.	.	.
Template Conservation							.	.	.	.	.																						.	.	.	.	.	.	.	.
Template Sequence		S	C	T	F	A	.	.	.	.	.	L	P	S	E	L	E	R	S	Y	Q	R	F	T	A	F	Y	A	S	R	H	S	.	.	.	.	.	.	.	.	G	R	K	L	T	W	L	Y	Q	L	S	K	G	E	L	V	T	N	C	F	K
Template Known Secondary structure			S				.	.	.	.	.																					T	.	.	.	.	.	.	.	.	T							G	G	G								T	T	S	S
Template Predicted Secondary structure							.	.	.	.	.																						.	.	.	.	.	.	.	.
Template SS confidence
		549	550	.	.	.						.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.									.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.
		1103	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	D	Q	T	L	H	V	S	L	N	T	V	Q	M	W	L	L	F	N	Q	S	E	E	V	S	V	E	T	L	L	R	N	S	D	L	S	P	E	L	L	H	Q	A	L	L	P	L	T	S	D	N	G	P	L	T	L	E	E	T	Q
Query Conservation
Alig confidence																																																		.
Template Conservation																																																		.
Template Sequence		N	R	Y	T	L	Q	A	S	T	F	Q	M	A	I	L	L	Q	Y	N	T	E	D	A	Y	T	V	Q	Q	L	T	D	S	T	Q	I	K	M	D	I	L	A	Q	V	L	Q	I	L	L	.	K	S	K	L	L	V	L	E	D	E	N
Template Known Secondary structure		S															G	G	G	G	T		S											T																.			T	S				S	S	S	S
Template Predicted Secondary structure																																																		.
Template SS confidence
		596	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.		.	.	.	.	.	.	650	.	.	.	.
		1163								.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180		.	.	.	.	.	.	.	.	.	1190	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.
Predicted Secondary structure			.	.	.	.	.	.	.																		.
Query SS confidence			.	.	.	.	.	.	.																		.
Query Sequence		D	.	.	.	.	.	.	.	Y	P	Q	G	G	V	L	R	L	R	E	P	R	S	Q	T	H	.	E	E	F	L	W	L	I	P	P	Q	T	Y	L	S	V	E	K	D	E	G	R	T	L	E	Q	K	R	N	L	L	S	C	L	L
Query Conservation			.	.	.	.	.	.	.																		.
Alig confidence			.	.	.	.	.	.	.																		.
Template Conservation
Template Sequence		A	N	V	D	E	V	E	L	K	P	D	T	L	I	K	L	Y	L	G	Y	K	N	K	K	L	R	V	N	I	N	V	P	M	K	T	E	Q	K	Q	E	Q	E	T	T	H	K	N	I	E	E	D	R	K	L	L	I	Q	A	A	I
Template Known Secondary structure				G	G	G					T	T	S							S				S	S	S
Template Predicted Secondary structure
Template SS confidence
		655	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.
		1215	.	.	.	.	1220	.	.	.	.	.	.	.	.	.	1230	.	.	.	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.	.	1250	.	.	.	.	.	.	.	.	.	1260	.	.	.	.	.	.	.	.	.	1270	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	R	I	L	K	A	H	R	E	K	G	L	H	I	D	Q	L	V	C	L	V	L	E	A	W	Q	K	G	P	D	P	P	G	R	L	G	N	A	A	A	V	G	V	A	C	S	S	T	D	V	L	S	C	I	L	H	L	L	G	Q
Query Conservation
Alig confidence								.	.																				.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation								.	.																				.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		V	R	I	M	K	M	.	.	R	K	V	L	K	H	Q	Q	L	L	G	E	V	L	T	Q	L	S	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	R	F	K	P	R	V	P	V	I	K	K	C	I	D	I	L	I	E	K
Template Known Secondary structure						T	S	.	.	S	S																T	T	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T																		T
Template Predicted Secondary structure								.	.																				.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		715	.	.	.	.	720			.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.															740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.
		1275	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	Y	V	E	R	R	D	D	R	P	Q	V	L	M	Y	A	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	Y	L	E	R	V	D	G	E	K	D	T	Y	S	Y	L	A
Template Known Secondary structure		T	S					T	T
Template Predicted Secondary structure
Template SS confidence
		759	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.