Job Description P35235 Confidence 100.00% Date Wed Jul 10 14:25:20 BST 2013 Rank 41 Aligned Residues 262 % Identity 29% Template c4az1B_ PDB info PDB header:hydrolase Chain: B: PDB Molecule:tyrosine specific protein phosphatase; PDBTitle: crystal structure of the trypanosoma cruzi protein tyrosine2 phosphatase tcptp1, a potential therapeutic target for chagas'3 disease Resolution 2.18 Å

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		245	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	G	F	W	E	E	F	E	T	L	Q	Q	Q	E	C	K	L	L	Y	S	R	K	E	G	Q	R	Q	E	N	K	N	K	N	R	Y	K	N	I	L	P	F	D	H	T	R	V	V	L	H	D	G	D	P	N	E	P	V	S	D	Y
Query Conservation
Alig confidence																							.	.
Template Conservation																							.	.
Template Sequence		E	R	V	Q	R	E	F	S	L	L	L	R	Q	E	D	P	R	S	I	S	F	.	.	A	T	S	L	K	N	R	H	K	N	R	Y	L	D	I	L	A	N	E	A	T	L	Y	P	Q	V	T	D	A	P	G	A	S	T	P	Y	Y
Template Known Secondary structure												T	T	S			G	G	G				.	.						T	G	G	G		S		T	T					T	T	T	B	T	T	G	G	G			S	S				S
Template Predicted Secondary structure																							.	.
Template SS confidence
		19	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.			40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.
		305	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	N	A	N	I	I	M	P	E	F	E	T	K	C	N	N	S	K	P	K	K	S	Y	I	A	T	Q	G	C	L	Q	N	T	V	N	D	F	W	R	M	V	F	Q	E	N	S	R	V	I	V	M	T	T	K	E	V	E	R	G	K
Query Conservation
Alig confidence								.	.	.	.	.	.	.	.	.
Template Conservation								.	.	.	.	.	.	.	.	.
Template Sequence		I	N	G	N	L	I	.	.	.	.	.	.	.	.	.	D	L	D	L	P	H	K	F	V	A	C	Q	A	P	V	V	Q	G	I	P	D	F	L	A	M	L	Y	E	K	K	I	S	L	V	I	M	V	T	K	L	E	E	G	G	F
Template Known Secondary structure			S					.	.	.	.	.	.	.	.	.			S	S	S											G	G	G											T	T								S		S			T	T
Template Predicted Secondary structure								.	.	.	.	.	.	.	.	.
Template SS confidence
		77	.	.	80	.	.										.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.
		365	.	.	.	.	370	.	.	.	.	.	.	.				.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.							.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.
Predicted Secondary structure															.	.	.																					.	.	.	.	.	.
Query SS confidence															.	.	.																					.	.	.	.	.	.
Query Sequence		S	K	C	V	K	Y	W	P	D	E	Y	A	L	.	.	.	K	E	Y	G	V	M	R	V	R	N	V	K	E	S	A	A	H	D	Y	T	.	.	.	.	.	.	L	R	E	L	K	L	S	K	V	G	Q	A	L	L	Q	G	N	T
Query Conservation															.	.	.																					.	.	.	.	.	.
Alig confidence															.	.	.																					.	.	.	.	.	.									.	.	.	.	.
Template Conservation																																																				.	.	.	.	.
Template Sequence		V	K	A	D	R	Y	W	P	E	E	R	G	S	G	S	I	A	V	S	G	N	C	G	L	T	I	S	E	D	P	G	K	A	Y	E	V	E	D	E	L	K	I	T	R	R	Y	L	I	L	Q	.	.	.	.	.	R	A	D	E	P
Template Known Secondary structure								S			S	S	S							S	S	S	S								T	T	S						T	T	T	T										.	.	.	.	.		T	T	S
Template Predicted Secondary structure																																																				.	.	.	.	.
Template SS confidence
		128	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.						.	.	180	.	.
		416	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	R	T	V	W	Q	Y	H	F	R	T	W	P	D	H	G	V	P	S	D	P	G	G	V	L	D	F	L	E	E	V	H	H	K	Q	E	S	I	V	D	A	G	P	V	V	V	H	C	S	A	G	I	G	R	T	G	T	F	I	V
Query Conservation
Alig confidence																																	.	.	.	.
Template Conservation																																	.	.	.	.
Template Sequence		P	H	K	F	T	Q	V	Q	Y	T	G	W	P	D	H	G	I	P	Q	S	A	T	S	L	E	A	L	L	T	N	V	.	.	.	.	K	N	S	P	T	T	V	P	V	V	V	H	C	S	A	G	I	G	R	T	G	T	L	I	G
Template Known Secondary structure												S			T	T	S			S													.	.	.	.			S		S	S	S							S	S	S	S	S
Template Predicted Secondary structure																																	.	.	.	.
Template SS confidence
		183	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.					.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.
		476	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	D	I	L	I	D	I	I	R	E	K	G	V	D	C	D	I	D	V	P	K	T	I	Q	M	V	R	S	Q	R	S	G	M	V	Q	T	E	A	Q	Y	R	F	I	Y	M	A	V	Q	H	Y	I	E
Query Conservation
Alig confidence														.
Template Conservation														.
Template Sequence		A	Y	A	A	L	T	H	L	E	R	G	T	.	L	T	D	T	T	V	Y	D	V	V	S	A	M	R	R	Q	R	F	G	M	V	Q	R	M	E	Q	Y	F	V	I	Y	L	T	L	M	C	R	L	G
Template Known Secondary structure												T		.			T	T													S	T	T		S		S													T	T	T	T
Template Predicted Secondary structure														.
Template SS confidence
		239	240	.	.	.	.	.	.	.	.	.	250		.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D