Job Description P35235 Confidence 100.00% Date Wed Jul 10 14:25:20 BST 2013 Rank 26 Aligned Residues 274 % Identity 38% Template c2h04A_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:protein tyrosine phosphatase, receptor type, b,; PDBTitle: structural studies of protein tyrosine phosphatase beta2 catalytic domain in complex with inhibitors Resolution 2.30 Å

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		221	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Predicted Secondary structure
Query SS confidence
Query Sequence		I	N	A	A	E	I	E	S	R	V	R	E	L	S	K	L	A	E	T	T	D	K	V	K	Q	G	F	W	E	E	F	E	T	L	Q	Q	Q	E	C	K	L	L	Y	S	R	K	E	G	Q	R	Q	E	N	K	N	K	N	R	Y	K
Query Conservation
Alig confidence																				.	.	.	.	.	.																						.	.
Template Conservation																				.	.	.	.	.	.																						.	.
Template Sequence		I	K	I	N	Q	F	E	G	H	F	M	K	L	Q	A	D	S	N	.	.	.	.	.	.	Y	L	L	S	K	E	Y	E	E	L	K	D	V	G	R	N	Q	S	C	D	I	.	.	A	L	L	P	E	N	R	G	K	N	R	Y	N
Template Known Secondary structure				G	G	G									T					.	.	.	.	.	.										T	T	T	T	T	T	T	S			T	T	.	.	T	T	S	G	G	G	G	G	G		S	S	T
Template Predicted Secondary structure																				.	.	.	.	.	.																						.	.
Template SS confidence
		1683	.	.	.	.	.	.	1690	.	.	.	.	.	.	.	.	.	1700							.	.	.	.	.	.	.	.	.	1710	.	.	.	.	.	.	.	.	.	1720	.			.	.	.	.	.	.	.	.	1730	.	.	.	.
		281	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340
Predicted Secondary structure
Query SS confidence
Query Sequence		N	I	L	P	F	D	H	T	R	V	V	L	H	D	G	D	P	N	E	P	V	S	D	Y	I	N	A	N	I	I	M	P	E	F	E	T	K	C	N	N	S	K	P	K	K	S	Y	I	A	T	Q	G	C	L	Q	N	T	V	N	D
Query Conservation
Alig confidence																.	.	.	.	.	.	.										.	.	.	.	.	.	.	.
Template Conservation																.	.	.	.	.	.	.										.	.	.	.	.	.	.	.
Template Sequence		N	I	L	P	Y	D	A	T	R	V	K	L	S	N	.	.	.	.	.	.	.	S	D	Y	I	N	A	S	Y	I	.	.	.	.	.	.	.	.	P	G	N	N	F	R	R	E	Y	I	V	T	Q	G	P	L	P	G	T	K	D	D
Template Known Secondary structure		T			B		T	T	T							.	.	.	.	.	.	.										.	.	.	.	.	.	.	.			S	S		T	T										T	T	T
Template Predicted Secondary structure																.	.	.	.	.	.	.										.	.	.	.	.	.	.	.
Template SS confidence
		1735	.	.	.	.	1740	.	.	.	.	.	.	.	.								.	1750	.	.	.	.	.	.	.									.	.	1760	.	.	.	.	.	.	.	.	.	1770	.	.	.	.	.	.	.	.	.
		341	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400
Predicted Secondary structure
Query SS confidence
Query Sequence		F	W	R	M	V	F	Q	E	N	S	R	V	I	V	M	T	T	K	E	V	E	R	G	K	S	K	C	V	K	Y	W	P	D	E	Y	A	L	K	E	Y	G	V	M	R	V	R	N	V	K	E	S	A	A	H	D	Y	T	L	R	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		F	W	K	M	V	W	E	Q	N	V	H	N	I	V	M	V	T	Q	C	V	E	K	G	R	V	K	C	D	H	Y	W	P	A	D	Q	D	S	L	Y	Y	G	D	L	I	L	Q	M	L	S	E	S	V	L	P	E	W	T	I	R	E
Template Known Secondary structure									T	T								S		S			T	T				S				S		S	S	S	S					T	T												S	S
Template Predicted Secondary structure
Template SS confidence
		1786	.	.	.	1790	.	.	.	.	.	.	.	.	.	1800	.	.	.	.	.	.	.	.	.	1810	.	.	.	.	.	.	.	.	.	1820	.	.	.	.	.	.	.	.	.	1830	.	.	.	.	.	.	.	.	.	1840	.	.	.	.	.
		401	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460
Predicted Secondary structure
Query SS confidence
Query Sequence		L	K	L	S	K	V	G	Q	A	L	L	Q	G	N	T	E	R	T	V	W	Q	Y	H	F	R	T	W	P	D	H	G	V	P	S	D	P	G	G	V	L	D	F	L	E	E	V	H	H	K	Q	E	S	I	V	D	A	G	P	V	V
Query Conservation
Alig confidence						.	.	.	.	.	.	.	.	.
Template Conservation						.	.	.	.	.	.	.	.	.
Template Sequence		F	K	I	C	.	.	.	.	.	.	.	.	.	G	E	H	R	L	I	R	H	F	H	Y	T	V	W	P	D	H	G	V	P	E	T	T	Q	S	L	I	Q	F	V	R	T	V	R	D	Y	I	N	R	S	P	G	A	G	P	T	V
Template Known Secondary structure						.	.	.	.	.	.	.	.	.																T	T	S			S																		T	S	T	T
Template Predicted Secondary structure						.	.	.	.	.	.	.	.	.
Template SS confidence
		1846	.	.	.										1850	.	.	.	.	.	.	.	.	.	1860	.	.	.	.	.	.	.	.	.	1870	.	.	.	.	.	.	.	.	.	1880	.	.	.	.	.	.	.	.	.	1890	.	.	.	.	.	.
		461	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520
Predicted Secondary structure
Query SS confidence
Query Sequence		V	H	C	S	A	G	I	G	R	T	G	T	F	I	V	I	D	I	L	I	D	I	I	R	E	K	G	V	D	C	D	I	D	V	P	K	T	I	Q	M	V	R	S	Q	R	S	G	M	V	Q	T	E	A	Q	Y	R	F	I	Y	M
Query Conservation
Alig confidence																													.	.	.
Template Conservation																													.	.	.
Template Sequence		V	H	C	S	A	G	V	G	R	T	G	T	F	I	A	L	D	R	I	L	Q	Q	L	D	S	K	D	.	.	.	S	V	D	I	Y	G	A	V	H	D	L	R	L	H	R	V	H	M	V	Q	T	E	C	Q	Y	V	Y	L	H	Q
Template Known Secondary structure					S	S	S	S																T	T	T		S	.	.	.															B	T	T	S	S		S
Template Predicted Secondary structure																													.	.	.
Template SS confidence
		1902	.	.	.	.	.	.	.	1910	.	.	.	.	.	.	.	.	.	1920	.	.	.	.	.	.	.	.				.	1930	.	.	.	.	.	.	.	.	.	1940	.	.	.	.	.	.	.	.	.	1950	.	.	.	.	.	.	.	.
		521	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	V	Q	H	Y	I	E	T	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		C	V	R	D	V	L	R	A	R
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		1959	1960	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D