Job Description Q9Z0R4 Confidence 100.00% Date Tue Jul 30 13:06:10 BST 2013 Rank 4 Aligned Residues 348 % Identity 27% Template c1x86A_ PDB info PDB header:signaling protein/membrane protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 12; PDBTitle: crystal structure of the dh/ph domains of leukemia-associated rhogef2 in complex with rhoa Resolution 3.22 Å Model Dimensions (Å) X:70.738 Y:92.657 Z:44.126

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		1209	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.	.	.	1230	.	.	.	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.	.	1250	.	.	.	.	.	.	.	.	.	1260	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	P	S	Q	Q	W	C	S	D	L	H	L	L	D	M	L	T	P	T	E	R	K	R	Q	G	Y	I	H	E	L	I	V	T	E	E	N	Y	V	N	D	L	Q	L	V	T	E	I	F	Q	K	P	L	T	E	S	E	L	L	T	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	P	N	W	Q	Q	L	V	S	R	E	V	L	L	G	L	K	P	C	E	I	K	R	Q	E	V	I	N	E	L	F	Y	T	E	R	A	H	V	R	T	L	K	V	L	D	Q	V	F	Y	Q	R	V	S	R	E	G	I	L	S	P
Template Known Secondary structure					G	G	G	T	S						T	T	S		T	T																													T								S		S
Template Predicted Secondary structure
Template SS confidence
		766	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.
		1269	1270	.	.	.	.	.	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.	.	.	.	.	.	.	1310	.	.	.	.	.	.							.	.	.	1320	.	.
Predicted Secondary structure																																																		.	.	.	.	.	.
Query SS confidence																																																		.	.	.	.	.	.
Query Sequence		K	E	V	A	M	I	F	V	N	W	K	E	L	I	M	C	N	I	K	L	L	K	A	L	R	V	R	K	K	M	S	G	E	K	M	P	V	K	M	I	G	D	I	L	S	A	Q	L	.	.	.	.	.	.	P	H	M	Q	P	Y
Query Conservation																																																		.	.	.	.	.	.
Alig confidence																																	.																	.	.	.	.	.	.
Template Conservation																																	.
Template Sequence		S	E	L	R	K	I	F	S	N	L	E	D	I	L	Q	L	H	I	G	L	N	E	Q	M	K	A	V	R	K	R	N	.	E	T	S	V	I	D	Q	I	G	E	D	L	L	T	W	F	S	G	P	G	E	E	K	L	K	H	A	A
Template Known Secondary structure									T	T																							.	S	S	S	S													S
Template Predicted Secondary structure																																	.
Template SS confidence
		826	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.		.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.
		1323	.	.	.	.	.	.	1330	.	.	.	.	.	.	.	.	.	1340	.	.	.	.	.	.	.	.	.	1350	.	.	.	.	.	.	.	.	.	1360	.	.	.	.	.	.	.	.	.	1370	.	.	.	.	.	.	.	.	.	1380	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	R	F	C	S	C	Q	L	N	G	A	A	L	I	Q	Q	K	T	D	E	A	P	D	F	K	E	F	V	K	R	L	A	M	D	P	R	C	K	G	M	P	L	S	S	F	I	L	K	P	M	Q	R	V	T	R	Y	P	L	I	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	T	F	C	S	N	Q	P	F	A	L	E	M	I	K	S	R	Q	K	K	D	S	R	F	Q	T	F	V	Q	D	A	E	S	N	P	L	C	R	R	L	Q	L	K	D	I	I	P	T	Q	M	Q	R	L	T	K	Y	P	L	L	L
Template Known Secondary structure							T																											T	S	G	G	G	T	T							T	T
Template Predicted Secondary structure
Template SS confidence
		885	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.
		1383	.	.	.	.	.	.	1390	.	.	.	.	.	.	.	.	.	1400	.	.	.	.	.	.	.	.	.	1410	.	.	.	.	.	.	.	.	.	1420	.	.	.	.	.	.	.	.	.	1430	.	.	.	.	.	.	.				.	.
Predicted Secondary structure																																																									.	.	.
Query SS confidence																																																									.	.	.
Query Sequence		K	N	I	L	E	N	T	P	E	N	H	P	D	H	S	H	L	K	H	A	L	E	K	A	E	E	L	C	S	Q	V	N	E	G	V	R	E	K	E	N	S	D	R	L	E	W	I	Q	A	H	V	Q	C	E	G	.	.	.	L	S
Query Conservation																																																									.	.	.
Alig confidence											.																																														.	.	.
Template Conservation											.
Template Sequence		D	N	I	A	K	Y	T	E	W	.	P	T	E	R	E	K	V	K	K	A	A	D	H	C	R	Q	I	L	N	F	V	N	Q	A	V	K	E	A	E	N	K	Q	R	L	E	D	Y	Q	R	R	L	D	T	S	S	L	K	L	S	E
Template Known Secondary structure							T				.																																								T				S	S			S	S	S
Template Predicted Secondary structure											.
Template SS confidence
		945	.	.	.	.	950	.	.	.		.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.
		1440	.	.	.	.	.	.	.	.	.	1450	.	.	.	.	.	.	.	.	.	1460	.	.	.	.	.	.	.	.				.	1470	.	.	.	.	.	.	.	.	.	1480	.	.	.	.	.	.	.	.	.	1490	.	.	.	.	.	.
Predicted Secondary structure																															.	.	.
Query SS confidence																															.	.	.
Query Sequence		E	Q	L	V	F	N	S	V	T	N	C	L	G	P	R	K	F	L	H	S	G	K	L	Y	K	A	K	S	N	.	.	.	K	E	L	Y	G	F	L	F	N	D	F	L	L	L	T	Q	I	T	K	P	L	G	S	S	G	T	D	K
Query Conservation																															.	.	.
Alig confidence																															.	.	.
Template Conservation
Template Sequence		Y	P	N	V	E	E	L	R	N	L	D	L	T	K	R	K	M	I	H	E	G	P	L	V	W	K	V	N	R	D	K	T	I	D	L	Y	T	L	L	L	E	D	I	L	V	L	L	Q	K	Q	D	D	R	L	V	L	R	C	H	S
Template Known Secondary structure			G	G	G					S			G	G	G	S												S		T	T											S	S							B		S	S
Template Predicted Secondary structure
Template SS confidence
		1004	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.
		1497	.	.	1500	.	.	.	.	.	.	.	.	.	1510	.	.	.	.	.	.	.	.	.	1520	.		.	.	.	.	.	.	.	.	1530	.	.	.	.	.	.	.	.	.	1540	.	.	.	.	.	.	.	.	.	1550	.	.	.	.	.
Predicted Secondary structure																											.
Query SS confidence																											.
Query Sequence		V	F	S	P	K	S	N	L	Q	Y	K	M	Y	K	T	P	I	F	L	N	E	V	L	V	K	.	L	P	T	D	P	S	G	D	E	P	I	F	H	I	S	H	I	D	R	V	Y	T	L	R	A	E	S	I	N	E	R	T	A	W
Query Conservation																											.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.															.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	T	F	S	P	V	I	K	L	S	T	V	L	V	R	Q	V	A	T	D	N	K	A	L	F	V	I	S	M	S	D	N	G	A	Q	I	Y	E	L	V	A	Q	T	V	S	E	K	T	V	W
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.				S				T	T	S							S	S	S	T	T							B		S	S		B								S	S
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
													1075	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.
		1556	.	.	.	1560	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	Q	K	I	K	A	A	S	E	L	Y	I	E	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Q	D	L	I	C	R	M	A	A	S	V	K	E	Q
Template Known Secondary structure														T
Template Predicted Secondary structure
Template SS confidence
		1124	.	.	.	.	.	1130	.	.	.	.	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D