Return to main results Retrieve Phyre Job Id

Job DescriptionQ5SQX6
Confidence94.13%DateWed Jul 10 14:11:20 BST 2013
Rank2Aligned Residues872
% Identity15%Templatec3p8cB_
PDB info PDB header:protein bindingChain: B: PDB Molecule:nck-associated protein 1; PDBTitle: structure and control of the actin regulatory wave complex
Resolution2.29 Å
Model Dimensions (Å)X:149.944 Y:86.865 Z:104.861

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   64.....70.........80........ .90.........100
Predicted Secondary structure  .......................




Query SS confidence 
























. . . . . . . . . . . . . . . . . . . . . . .











Query Sequence  TVHSSMNEMLEEGHDYAVMLYTWRS. . . . . . . . . . . . . . . . . . . . . . . CSRAIPQVKCNE
Query Conservation       

  

 
    
 


 

.......................





 
  
 
Alig confidence 
























.......................







.


Template Conservation     
   

     


 
 
 
 
     
        
  
   
 
  


 
.
  
Template Sequence  KLAEKLTILNDRGVGMLTRLYNIKKACGDPKAKPSYLIDKNLESAVKFIVRKFPAV. ENQ
Template Known Secondary structure 
STTTS
GGGT
TTTTT

.


Template Predicted Secondary structure 






















.


Template SS confidence 



























































   12.......20.........30.........40.........50.........60....... ..70
 
   101.... ....110.........120.........130.........140.........150.. ......
Predicted Secondary structure 
.







.

Query SS confidence 




.














































.





Query Sequence  QPNRV. EIYEKTVEVLEPEVTKLMKFMYFQRKAIERFCSEVKRLCHAERRKDF. VSEAYL
Query Conservation 
 
  .


 

 


 


 

     
   

  
   

 
   
     . 

  
Alig confidence 




.














































.





Template Conservation   
             
   
 
  
 
 
      

 

      


  
  

   
Template Sequence  QLAQLQKEKSEILKNLALYYFTFVDVMEFKDHVCELLNTIDVCQVFFDITVNFDLTKNYL
Template Known Secondary structure  TTTT



TTTS
Template Predicted Secondary structure 






Template SS confidence 



























































   75....80.........90.........100.........110.........120.........130....
 
   159160.........170........ .180.........190.........200.........210......
Predicted Secondary structure  ..




Query SS confidence 



















. .





































Query Sequence  LTLGKFINMFAVLDELKNMK. . CSVKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLAN
Query Conservation   

 


     

 


 
..


 

 
  


  

 
  
     
   
  


 
Alig confidence 



















..









......







....









Template Conservation 



 
 

 

 
 
  

 
   

     ......       
....
 

 
 
  
Template Sequence  DLIITYTTLMILLSRIEERKAIIGLYNYAHEM. . . . . . THGASDRE. . . . YPRLGQMIVD
Template Known Secondary structure  T
TTT......TSSS

TT....
Template Predicted Secondary structure 

......






....
Template SS confidence 



























































   135....140.........150.........160...... ...170.... .....180....
 
   217..220.........230.. .......240. ........250.........260
Predicted Secondary structure 



.
......






.........
Query SS confidence 















.








. . . . . .


















. . . . . . . . .
Query Sequence  HNRITQCLHQQLEVIP. GYEELLADI. . . . . . VNICVDYYENKMYLTPSEK. . . . . . . . .
Query Conservation    

   
   
  
 . 




  
......   
    
   

 
 

.........
Alig confidence 















.








......


















.........
Template Conservation   
 


 
 
 
      
   
 

    
   
 
 
 
    


   
      
 
Template Sequence  YENPLKKMMEEFVPHSKSLSDALISLQMVYPRRNLSADQWRNAQLLSLISAPSTMLNPAQ
Template Known Secondary structure  TSSTTTTGGGGTS

TTTT
SSSSGGGTTS


Template Predicted Secondary structure 


























Template SS confidence 



























































   185....190.........200.........210.........220.........230.........240....
 
   261...... ..270.........280.........290.........300.........310
Predicted Secondary structure  ..........















Query SS confidence  . . . . . . .






. . .










































Query Sequence  . . . . . . . HMLLKVM. . . GFGLYLMDGNVSNIYKLDAKKRINLSKIDKFFKQLQVVPLFGD
Query Conservation  .......  

 

... 
 
 
 
            

  
  
 



  




 

Alig confidence  .......






...









...






...



















Template Conservation   
 
  

       


 

 
  
 ... 
     ...   
    
 
   
 
 

Template Sequence  SDTMPCEYLSLDAMEKWIIFGFILCHG. . . ILNTDAT. . . ALNLWKLALQSSSCLSLFRD
Template Known Secondary structure 
TTS
TT...
...TT
STT
Template Predicted Secondary structure 








...




...





Template SS confidence 



























































   245....250.........260.........270. ....... .280.........290........
 
   311........320.........330.........340.........350.........360.........370
Predicted Secondary structure 




























Query SS confidence 



























































Query Sequence  MQIELARYIKTSAHYEENKSKWTCTQSSISPQYNICEQMVQIRDDHIRFISELARYSNSE
Query Conservation 
 
     

  
                  

 
      

 
   
   

   
  
Alig confidence 











..













































Template Conservation 
 
 

      ..    
   
    


    
   
   
  

  

  
 

   
Template Sequence  EVFHIHKAAEDL. . FVNIRGYNKRINDIRECKEAAVSHAGSMHRERRKFLRSALKELATV
Template Known Secondary structure  ..TT
GGGTT
Template Predicted Secondary structure  ..












Template SS confidence 



























































   299300.........310 .........320.........330.........340.........350......
 
   371........380.........390.........400.........410.........420.........430
Predicted Secondary structure 



















Query SS confidence 



























































Query Sequence  VVTGSGLDSQKSDEEYRELFDLALRGLQLLSKWSAHVMEVYSWKLVHPTDKFCNKDCPGT
Query Conservation      
             
 
  
 





 

  
 

 



  
 
   
   
  
Alig confidence 












...............




















....






Template Conservation    


 

 


 ............... 

 


 
  

 
 


 
....    

 
Template Sequence  LSDQPGLLGPKAL. . . . . . . . . . . . . . . FVFMALSFARDEIIWLLRHAD. . . . NMPKKSA
Template Known Secondary structure 
GGGGTTT...................S

SST
Template Predicted Secondary structure 








...............

....






Template SS confidence 



























































   357..360......... 370.........380.........390 .......
 
   431........440.........450.........460.........470.........480. .....
Predicted Secondary structure 



....
Query SS confidence 


















































. . . .




Query Sequence  AEEYERATRYNYTSEEKFAFVEVIAMIKGLQVLMGRMESVFNQAIRNTIYA. . . . ALQDF
Query Conservation     









 

  











  

   
  
   
   
  .... 

 
Alig confidence 






............































....




Template Conservation   
 

  ............
  

  
  
  



    



 
 


  

  
   
Template Sequence  DDFIDKH. . . . . . . . . . . . IAELIFYMEELRAHVRKYGPVMQRYYVQYLSGFDAVVLNEL
Template Known Secondary structure  TTT

TT............ST
Template Predicted Secondary structure  ............
Template SS confidence 



























































   398.400.... .....410.........420.........430.........440.....
 
   487.. 490.........500.........510.........520.........530.........540.
Predicted Secondary structure  .....

























Query SS confidence 


. . . . .



















































Query Sequence  AQV. . . . . TLREPLRQAVRKKKNVLISVLQAIRKTICDWEGGREPPNDPCLRGEKDPKGG
Query Conservation 

 ..... 
  

    



     

  

 
  

  
 
   
      

    
Alig confidence 


.....





..........






















.............
Template Conservation 
    
      
 .......... 
    

  


 
 
 
  

.............
Template Sequence  VQNLSVCPEDESII. . . . . . . . . . MSSFVNTMTSLSVKQVEDGEVFD. . . . . . . . . . . . .
Template Known Secondary structure  TT
S


..........T

TT



.............
Template Predicted Secondary structure 






..........










.............
Template SS confidence 



























































   446...450......... 460.........470.........480..
 
   542.......550.........560.........570.........580.........590.........600.
Predicted Secondary structure 



























Query SS confidence 



























































Query Sequence  FDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLDGPIVLAIEDFHKQSFFF
Query Conservation         
 
 

  

  


 
  

   
  
    
 
       
  

  
  
Alig confidence  ...........











.






........




















Template Conservation  ...........   

  
 

 .   
  
........
   
  
  
   

 
  
Template Sequence  . . . . . . . . . . . FRGMRLDWFRLQ. AYTSVSK. . . . . . . . ASLGLADHRELGKMMNTIIFH
Template Known Secondary structure  ...........
.STT........
SS
GGG
Template Predicted Secondary structure  ...........


.
........







Template SS confidence 



























































   483......490.... .....500. ........510.........520..
 
   602.... ...610.........620.........630.........640.........650.... .....
Predicted Secondary structure  .









.

Query SS confidence 




.















































.




Query Sequence  THLLN. ISEALQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILET. KEPSM
Query Conservation    

 .   

    


 









     





 





 



  .  
 
Alig confidence 




.















....................











.




Template Conservation 
   
     
 
   
  

 ....................
   
 
 
  
   

 
Template Sequence  TKMVDSLVEMLVETSDLSIFCF. . . . . . . . . . . . . . . . . . . . YSRAFEKMFQQCLELPSQ
Template Known Secondary structure 


GGGGG....................
S
Template Predicted Secondary structure 




....................




Template SS confidence 



























































   523......530.........540.... .....550.........560..
 
   660.........670..... ....680.........690.........700.......
Predicted Secondary structure 
............
Query SS confidence 















. . . . . . . . . . . .































Query Sequence  MEYVLYPLDLYNDSAY. . . . . . . . . . . . YALTKFKKQFLYDEIEAEVNLCFDQFVYKLAD
Query Conservation   
 











 ............ 

  





















 



Alig confidence 




...







............































Template Conservation       ...
   
   
        


             
 
    
    

  
 
Template Sequence  SRYSI. . . AFPLLCTHFMSCTHELCPEERHHIGDRSLSLCNMFLDEMAKQARNLITDICT
Template Known Secondary structure  TTTT...GGGGGGG

TT
GGG
Template Predicted Secondary structure 

...








Template SS confidence 



























































   563.... ..570.........580.........590.........600.........610.........
 
   708.710.........720.........730.........740..... .
Predicted Secondary structure 










.....................
Query SS confidence 





































. . . . . . . . . . . . . . . . . . . . .
Query Sequence  QIFAYYKAMAGSVLLDKRFRAECKNYGVIIPYPPSNRY. . . . . . . . . . . . . . . . . . . . . E
Query Conservation   

  


 
 
  

   
 
           
  
 ..................... 
Alig confidence 
......






























.....................
Template Conservation 
......   
  

 

  
  
 
     


 

    
  
  

     
  

 
Template Sequence  E. . . . . . QCTLSDQLLPKHCAKTISQAVNKEKPGVESMRKNRLVVTNLDKLHTALSELCF
Template Known Secondary structure  ......TTSGGGGTT


TTGGG

S
TTS

Template Predicted Secondary structure  ......
























Template SS confidence 



























































   620 .........630.........640.........650.........660.........670...
 
   747..750.........760.........770.........780... ......790.........800...
Predicted Secondary structure 




...



Query SS confidence 




































. . .



















Query Sequence  TLLKQRHVQLLGRSIDLNRLITQRISAAMYKSLDQAI. . . SRFESEDLTSIVELEWLLEI
Query Conservation   




 
 



 



 






  
   

 

... 



 

  




 

 
Alig confidence 




































...


..














Template Conservation   

    
 
  
 
   


   
   
   
          ..  
 


 

  
  
Template Sequence  SINYVPNMVVWEHTFTPREYLTSHLEIRFTKSIVGMTMYNQAT. . QEIAKPSELLTSVRA
Template Known Secondary structure  TS
S
TT
TT
BTTT..TB


Template Predicted Secondary structure 


















..





Template SS confidence 



























































   688.690.........700.........710.........720.........730 .........740.....
 
   804.....810.........820.........830....... ..840.........850....
Predicted Secondary structure 











........




.
Query SS confidence 

































. . . . . . . .
















.
Query Sequence  NRLTHRLLCKHMTLDSFDAMFREANHNVSAPYGR. . . . . . . . ITLHVFWELNFDFLPNY.
Query Conservation 

 

 



 
 

 

 
  

  
 

  

........

 

  

  
 



.
Alig confidence 

































........












.


.
Template Conservation     


 

  
 

 
  
   

 

  
 
 
  

  
    


 
    .    
Template Sequence  YMTVLQSIENYVQIDITRVFNNVLLQQTQHLDSHGEPTITSLYTNWYLETLLRQV. SNGH
Template Known Secondary structure  GGGTSS

TTSSB
TTS
B
T.TTS
Template Predicted Secondary structure 











.



Template SS confidence 



























































   746...750.........760.........770.........780.........790.........800 ....
 
   855....860.........870.........880.........890.........900.........910...
Predicted Secondary structure  .





































Query SS confidence  .


























































Query Sequence  . CYNGSTNRFVRTAIPFTQEPQRDKPANVQPYYLYGSKPLNIAYSHIYSSYRNFVGPPHF
Query Conservation  .
 
  
 




         

           


 

 
   
   
  
 
  

Alig confidence  .











......









................







......
Template Conservation 

 

    


 ......       
 
................
  

  
......
Template Sequence  IAYFPAMKAFVNL. . . . . . PTENELTFNA. . . . . . . . . . . . . . . . EEYSDISE. . . . . . M
Template Known Secondary structure  TTTT
......SSS



S
T................S......
Template Predicted Secondary structure 

......









................

......
Template SS confidence 



























































   805....810....... ..820....... ..830..... .
 
   914.....920.........930.........940.........950.........960.........970...
Predicted Secondary structure 













Query SS confidence 



























































Query Sequence  KTICRLLGYQGIAVVMEELLKIVKSLLQGTILQYVKTLIEVMPKICRLPRHEYGSPGILE
Query Conservation    
 



   

 

  


 
          

  
    

   

   

  

  
Alig confidence 


























.


















....








Template Conservation 


 






   
   
  

   
.  
  

 

 
 
     ....
  
     
Template Sequence  RSLSELLGPYGMKFLSESLMWHISSQV. AELKKLVVENVDVLTQMRT. . . . SFDKPDQMA
Template Known Secondary structure  .TT....
TT
Template Predicted Secondary structure 

.....



Template SS confidence 



























































   837..840.........850.........860... ......870.........880.. .......890.
 
   974.....980.........990.........1000.........1010.........1020.........1030...
Predicted Secondary structure 







Query SS confidence 



























































Query Sequence  FFHHQLKDIIEYAELKTDVFQSLREVGNAILFCLLIEQALSQEEVCDLLHAAPFQNILPR
Query Conservation       
       


  

   




 
    


  
       
  




   
 
Alig confidence  ......









.
























....













Template Conservation  ......     
   
.     

 

 

 

 




   ....
 
   
 
 
 
 
Template Sequence  . . . . . . ALFKRLSSVD. SVLKRMTIIGVILSFRSLAQEALRD. . . . VLSYHIPFLVSSIE
Template Known Secondary structure  ......TT


.....
Template Predicted Secondary structure  ......

.....

Template SS confidence 



























































   892.......900. ........910.........920...... ...930.........940
 
   1034.....1040.........1050...... ...1060.........1070.........1080.........1090..
Predicted Secondary structure 











.







Query SS confidence 






















.



































Query Sequence  VYIKEGERLEVRMKRLEAKYAPL. HLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMF
Query Conservation           
   
 
       .        
  
 
   
     
 

 
  
 
  
Alig confidence 






















.








........












....

Template Conservation       
      
 

    
     
  

  ........
            ....

Template Sequence  DFKDHDMKVAMNVYELSSAAGLPCEIDPALVVA. . . . . . . . LSSSPEEEYKIAC. . . . LL
Template Known Secondary structure 


SSTT


SS
........T

....
Template Predicted Secondary structure 














........


....
Template SS confidence 



























































   941........950.........960.........970... ......980...... ..
 
   1093......1100.........1110......
Predicted Secondary structure 







Query SS confidence 























Query Sequence  EVILTRIRSYLQDPIWRGPPPTNG
Query Conservation 
 

 
    
    
    
 

Alig confidence 























Template Conservation    
 
        
    

  
 
Template Sequence  MVFVAVSLPTLASNVMSQYSPAIE
Template Known Secondary structure  GGGGGG
GGG
TTTT
Template Predicted Secondary structure 
















Template SS confidence 























   1000.........1010.........1020...
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions
Phyre2 is part of Genome3D