|   |   |
366 | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | |
. | 390 | . | . | . | . | . | . | . | . | . | |
|
400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
| . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
S | E | L | T | F | V | Q | E | I | G | S | G | Q | F | G | L | V | H | L | G | Y | W | L | . |
N | K | D | K | V | A | I | K | T | I | Q | . |
. |
E | G | A | M | S | E | E | D | F | I | E | E | A | E | V | M | M | K | L | S | H | P | K |
| Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   | . |   |   |   |   |
|
|
|
|   |   |   | . | . |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|
|
|
| Template Sequence |   |
T | D | F | E | P | I | Q | C | L | G | R | G | G | F | G | V | V | F | E | A | K | N | K | V | D | D | C | N | Y | A | I | K | R | I | R | L | P | N | R | E | L | A | R | E | K | V | M | R | E | V | K | A | L | A | K | L | E | H | P | G |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| T | T |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
423 | . | . | . | . | . | . | 430 | . | . | . | . | |
|
. | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | |
|
. | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
| . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | V | Q | L | Y | G | V | C | L | E | Q | A | . |
. |
P | I | C | L | V | F | E | F | M | E | H | G | C | L | S | D | Y | L | R | S | Q | R | G | L | . |
. |
F | A | A | E | T | L | L | G | M | C | L | D | V | C | E | G | M | A | Y | L |
| Query Conservation |   |
|
|   |
|   |
|   |   |   |   |   |   | . | . |   |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   | . | . |
|   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|   |
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
| Template Sequence |   |
I | V | R | Y | F | N | A | W | L | E | K | N | K | V | Y | L | Y | I | Q | M | Q | L | C | R | K | E | N | L | K | D | W | M | N | G | R | C | T | I | E | E | R | E | R | S | V | C | L | H | I | F | L | Q | I | A | E | A | V | E | F | L |
| Template Known Secondary structure |   |
B |
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
| S |
|
|  |  |  |  |  |  | T |
|
| S | T | T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
479 | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |
|
|  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | K | A | C | V | I | H | R | D | L | A | A | R | N | C | L | V | G | E | N | Q | V | I | K | V | S | D | F | G | M | T | R | F | V | L | D | D | Q | Y | T | S | S | T | G | T | K | F | P | V | K | W | A | S | P | E | V | F | S | F | S |
| Query Conservation |   |
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |
|
|
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
H | S | K | G | L | M | H | R | D | L | K | P | S | N | I | F | F | T | M | D | D | V | V | K | V | G | D | F | G | L | G | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | L | Y | M | S | P | E | Q | I | H | G | N |
| Template Known Secondary structure |   |
 |  | T | T |
|
|
|
|
|
|
| G | G | G |  |  |  |
| T | T |
|
|  |  |  |
| S |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| T | T | S |
|  |  |  |  | T | T |
|
| Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
928 | . | 930 | . | . | . | . | . | . | . | . | . | 940 | . | . | . | . | . | . | . | . | . | 950 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
960 | . | . | . | . | . | . | . | . | . | 970 | . |
|   |
|   |   |
539 | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | Y | S | S | K | S | D | V | W | S | F | G | V | L | M | W | E | V | F | S | E | G | K | I | P | Y | E | N | R | S | N | S | E | V | V | E | D | I | S | T | G | F | R | L | Y | K | P | R | L | A | S | C | H | V | Y | Q | I | M | N | H |
| Query Conservation |   |
  |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |
|
|
|
|
|
|   |   |
|
|
|   |
|   | . |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
| Template Sequence |   |
S | Y | S | H | K | V | D | I | F | S | L | G | L | I | L | F | E | L | L | Y | . |
P | . |
. |
F | S | T | Q | M | E | R | V | R | T | L | T | D | V | R | N | L | K | F | P | P | L | F | T | Q | K | Y | P | C | E | Y | V | M | V | Q | D |
| Template Known Secondary structure |   |
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | . |
| . | . |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
| . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
999 | 1000 | . | . | . | . | . | . | . | . | . | 1010 | . | . | . | . | . | . | . | . | |
. | |
|
1020 | . | . | . | . | . | . | . | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | . | . | . | 1050 | . | . | . | . | . |
|   |
|   |   |
599 | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
C | W | K | E | K | P | E | D | R | P | P | F | S | Q | L | L | S |
| Query Conservation |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |
|
|   |   |
|   |
|   |   |
|
|
|   |
| Template Sequence |   |
M | L | S | P | S | P | M | E | R | P | E | A | I | N | I | I | E |
| Template Known Secondary structure |   |
 | T |
| S | S | G | G | G | S |
|
|  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1056 | . | . | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . | . |
|   |