Job Description Q03526 Confidence 100.00% Date Wed Jul 10 14:09:50 BST 2013 Rank 7 Aligned Residues 371 % Identity 35% Template c4fl2A_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch Resolution 2.19 Å Model Dimensions (Å) X:60.682 Y:84.730 Z:48.403

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.		.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.
Predicted Secondary structure																										.
Query SS confidence																										.
Query Sequence		L	E	T	Y	E	W	Y	N	K	S	I	S	R	D	K	A	E	K	L	L	L	D	T	G	.	K	E	G	A	F	M	V	R	D	S	R	T	P	G	T	Y	T	V	S	V	F	T	K	A	I	I	S	E	N	P	C	I	K	H	Y
Query Conservation																										.
Alig confidence																										.																							.	.	.	.	.	.
Template Conservation																																																	.	.	.	.	.	.
Template Sequence		H	E	K	M	P	W	F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	D	N	N	G	S	Y	A	L	C	L	L	H	.	.	.	.	.	.	E	G	K	V	L	H	Y
Template Known Secondary structure		G	G	G	S	T	T	B			S												S	S	S			T	T									T	T	T									.	.	.	.	.	.	T	T
Template Predicted Secondary structure																																																	.	.	.	.	.	.
Template SS confidence
		163	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.							210	.	.	.	.	.	.
		299	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.								350	.
Predicted Secondary structure																																																					.	.	.	.	.	.	.
Query SS confidence																																																					.	.	.	.	.	.	.
Query Sequence		H	I	K	E	T	N	D	S	P	K	R	Y	Y	V	A	E	K	Y	V	F	D	S	I	P	L	L	I	Q	Y	H	Q	Y	N	G	G	G	L	V	T	R	L	R	Y	P	V	C	S	W	R	Q	K	.	.	.	.	.	.	.	A	P
Query Conservation																																																					.	.	.	.	.	.	.
Alig confidence											.	.																																									.	.	.	.	.	.	.
Template Conservation											.	.
Template Sequence		R	I	D	K	D	K	T	G	K	.	.	L	S	I	P	E	G	K	K	F	D	T	L	W	Q	L	V	E	H	Y	S	Y	K	A	D	G	L	L	R	V	L	T	V	P	C	Q	K	I	G	T	Q	R	E	A	L	P	M	D	T	E
Template Known Secondary structure							T	T	S		.	.			S	T	T				B	S	S									T	T	B		T	T	S	S	S				S	B				S				T	T			G	G	G	S	G
Template Predicted Secondary structure											.	.
Template SS confidence
		217	.	.	220	.	.	.	.	.			.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.
		352	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.									.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390				.	.	.	.	.	.	.	.	.	400
Predicted Secondary structure																								.	.	.	.	.	.	.	.																		.	.	.
Query SS confidence																								.	.	.	.	.	.	.	.																		.	.	.
Query Sequence		V	T	A	G	L	R	Y	G	K	W	V	I	Q	P	S	E	L	T	F	V	Q	E	.	.	.	.	.	.	.	.	I	G	S	G	Q	F	G	L	V	H	L	G	Y	W	L	N	K	.	.	.	D	K	V	A	I	K	T	I	Q	E
Query Conservation																								.	.	.	.	.	.	.	.																		.	.	.
Alig confidence																								.	.	.	.	.	.	.	.																		.	.	.
Template Conservation
Template Sequence		V	Y	E	S	P	Y	A	D	P	E	E	I	R	P	K	E	V	Y	L	D	R	K	L	L	T	L	E	D	K	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N
Template Known Secondary structure		G	G	S		G	G	G	S	T	T	S				S	S	S	B			G	G	G												T	T											T	T												S
Template Predicted Secondary structure
Template SS confidence
		347	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.
		401	.	.	.	.				.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.
Predicted Secondary structure							.	.	.
Query SS confidence							.	.	.
Query Sequence		G	A	M	S	E	.	.	.	E	D	F	I	E	E	A	E	V	M	M	K	L	S	H	P	K	L	V	Q	L	Y	G	V	C	L	E	Q	A	P	I	C	L	V	F	E	F	M	E	H	G	C	L	S	D	Y	L	R	S	Q	R	G
Query Conservation							.	.	.
Alig confidence							.	.	.																										.
Template Conservation																																			.
Template Sequence		E	A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I	C	.	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q	N	R	H
Template Known Secondary structure		G	G	G		G	G	G																	T	T	B								.		S	S	S									T	T		B									T	T
Template Predicted Secondary structure																																			.
Template SS confidence
		407	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.		440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.
		458	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.
Predicted Secondary structure																																																													.
Query SS confidence																																																													.
Query Sequence		L	F	A	A	E	T	L	L	G	M	C	L	D	V	C	E	G	M	A	Y	L	E	K	A	C	V	I	H	R	D	L	A	A	R	N	C	L	V	G	E	N	Q	V	I	K	V	S	D	F	G	M	T	R	F	V	L	D	D	Q	.
Query Conservation																																																													.
Alig confidence		.																																																											.
Template Conservation		.
Template Sequence		.	V	K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N
Template Known Secondary structure		.	S																						T	T				S			S	G	G	G						T	T							T	T					T	T
Template Predicted Secondary structure		.
Template SS confidence
			466	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.
			517	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.
Predicted Secondary structure		.
Query SS confidence		.
Query Sequence		.	Y	T	S	S	T	G	T	K	F	P	V	K	W	A	S	P	E	V	F	S	F	S	R	Y	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	V	F	S	E	G	K	I	P	Y	E	N	R	S	N	S	E	V	V	E	D
Query Conservation		.
Alig confidence		.
Template Conservation
Template Sequence		Y	Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	G	S	E	V	T	A	M
Template Known Secondary structure					S		B	T	T	B		G	G	G	G																													T	T	T			S	S	T	T
Template Predicted Secondary structure
Template SS confidence
		525	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.
		576	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620
Predicted Secondary structure
Query SS confidence
Query Sequence		I	S	T	G	F	R	L	Y	K	P	R	L	A	S	C	H	V	Y	Q	I	M	N	H	C	W	K	E	K	P	E	D	R	P	P	F	S	Q	L	L	S	Q	L	A	E	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	E	K	G	E	R	M	G	C	P	A	G	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	A	A	V	E	L	R	L	R	N	Y
Template Known Secondary structure				T	T							T	T													T		S	S	T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		585	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D