|   |   |
354 | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | 380 | . | . | . | . | . | . | . | |
. | . | 390 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | G | L | R | Y | G | K | W | V | I | Q | P | S | E | L | T | F | V | Q | E | I | G | S | G | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | G | L | V | H | L | G | Y | W | . |
L | N | K | D | K | V | A | I | K | T | I | Q |
| Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |
|   |   |
|   |   | . |   |   |   |   |   |
|
|
|
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |
|   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
S | P | V | P | R | P | M | Y | L | V | S | N | H | R | V | L | I | N | D | F | N | Q | P | F | Q | H | W | Q | N | Q | P | Y | R | S | R | R | Y | F | F | G | E | D | Y | V | C | K | F | F | Y | Y | D | M | P | H | G | I | L | T | A | E |
| Template Known Secondary structure |   |
S | S |
|
|  |  |  |  |  |  |  | S | S |  |  |  |  | T | T |  |  |  |  |
| S |  |  |  |
|
| . |
|
|
|  |  |  |  |  |
| S | S |  |  |  |  |  |  |  | S | S |
| S | T | T |
| S |
|  |  |
| Template Predicted Secondary structure |   |
 |  |
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
199 | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . |
|   |
|   |   |
400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | |
. | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | G | A | M | S | E | E | D | F | I | E | E | A | E | V | M | M | K | L | . |
S | H | P | K | L | V | Q | L | Y | G | V | C | L | E | Q | A | P | I | C | L | V | F | E | F | M | E | H | G | C | L | S | D | Y | L | R | S | Q | R | G | L |
| Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
| . |   |
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |
| Template Sequence |   |
E | S | Q | R | N | K | Y | E | L | H | N | E | I | K | F | L | T | Q | P | P | A | G | F | D | A | P | A | V | L | A | H | G | E | N | A | Q | S | G | W | L | V | M | E | K | L | P | G | R | L | L | S | D | M | L | A | A | G | E | E | I |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
| T | T |
|
|
|
|
|  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |
|
|
| S |  |  |  |  |  |  |  |  | T | T |
|
|
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
267 | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . |
|   |
|   |   |
459 | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
F | A | A | E | T | L | L | G | M | C | L | D | V | C | E | G | M | A | Y | L | E | K | A | C | V | I | H | R | D | L | A | A | R | N | C | L | V | G | E | N | Q | V | I | K | V | S | D | F | G | M | T | R | F | V | L | D | D | Q | Y | T |
| Query Conservation |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |
|
|
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |
| Alig confidence |   |
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  | . | . | . | . |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|   |
|
|
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
D | . |
. |
. |
. |
R | E | K | I | L | G | S | L | L | R | S | L | A | A | L | E | K | Q | G | F | W | H | D | D | V | R | P | W | N | V | M | V | D | A | R | Q | H | A | R | L | I | D | F | G | S | I | V | T | T | P | S | W | P | T | N |
| Template Known Secondary structure |   |
| . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  | S |
|
|
| G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
|
| T | T |  |  | S |
|
|
|
| S |  |  |
| Template Predicted Secondary structure |   |
 | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
327 | |
|
|
|
. | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . |
|   |
|   |   |
519 | 520 | . | . | |
|
|
. | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | |
|
|
. | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . |
| Predicted Secondary structure |   |
 |  |
|
| . | . | . |
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
S | S | T | G | . |
. |
. |
T | K | F | P | V | K | W | A | S | P | E | V | F | S | F | S | R | Y | . |
. |
. |
S | S | K | S | D | V | W | S | F | G | V | L | M | W | E | V | F | S | E | G | K | I | P | Y | E | N | R | S | N | S | E | V |
| Query Conservation |   |
  |   |   |   | . | . | . |   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |   |   | . | . | . |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |
| Alig confidence |   |
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|
|
|   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
L | V | Q | S | F | F | V | F | V | N | E | L | F | F | N | L | P | Q | P | W | S | N | W | L | Y | A | V | W | Q | E | P | V | E | R | W | N | F | V | L | L | L | A | L | F | E | K | K | A | K | L | P | S | A | E | Q | Q | R | G | A | T |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| T | T |  |  |  |  |  |  |  |  |  | T | S |
| G | G | G |
| S |  |  |  |  |  |  |  |  |  | T | G | G | G | S |
|
| G | G | G | S | S |
|
|  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
386 | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . |
|   |
|   |   |
573 | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
| Query Sequence |   |
V | E | D | I | S |
| Query Conservation |   |
  |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
| Template Conservation |   |
  |   |   |
|   |
| Template Sequence |   |
E | Q | W | I | I |
| Template Known Secondary structure |   |
 |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|   |   |
463 | . | . | . | . |
|   |