Job Description Q03526 Confidence 100.00% Date Wed Jul 10 14:09:50 BST 2013 Rank 78 Aligned Residues 239 % Identity 29% Template c3vw6B_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor Resolution 2.40 Å

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		360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.		.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.
Predicted Secondary structure																															.
Query SS confidence																															.
Query Sequence		K	W	V	I	Q	P	S	E	L	T	F	V	Q	E	I	G	S	G	Q	F	G	L	V	H	L	G	Y	W	L	.	N	K	D	K	V	A	I	K	T	I	Q	E	G	A	M	S	E	E	D	F	I	E	E	A	E	V	M	M	K	L
Query Conservation																															.
Alig confidence																															.													.	.	.	.	.
Template Conservation																																												.	.	.	.	.
Template Sequence		E	Y	D	Y	E	Y	D	E	N	G	D	R	V	V	L	G	K	G	T	Y	G	I	V	Y	A	G	R	D	L	S	N	Q	V	R	I	A	I	K	E	I	P	E	.	.	.	.	.	Q	P	L	H	E	E	I	A	L	H	K	H	L
Template Known Secondary structure							B		T	T	S	S	B							S	S	S								T	T	T												.	.	.	.	.											T	T
Template Predicted Secondary structure																																												.	.	.	.	.
Template SS confidence
		672	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.						.	.	.	.	.	.	720	.	.	.	.	.	.
		419	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.			460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.
Predicted Secondary structure																																											.	.
Query SS confidence																																											.	.
Query Sequence		S	H	P	K	L	V	Q	L	Y	G	V	C	L	E	Q	A	P	I	C	L	V	F	E	F	M	E	H	G	C	L	S	D	Y	L	R	S	Q	R	G	L	F	.	.	A	A	E	T	L	L	G	M	C	L	D	V	C	E	G	M	A
Query Conservation																																											.	.
Alig confidence																																											.	.
Template Conservation
Template Sequence		K	H	K	N	I	V	Q	Y	L	G	S	F	S	E	N	G	F	I	K	I	F	M	E	Q	V	P	G	G	S	L	S	A	L	L	R	S	K	W	G	P	L	K	D	N	E	Q	T	I	G	F	Y	T	K	Q	I	L	E	G	L	K
Template Known Secondary structure				T	T	B										T	T										T	T		B								T	T				T	T
Template Predicted Secondary structure
Template SS confidence
		733	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.
		477	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.		.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.
Predicted Secondary structure																					.
Query SS confidence																					.
Query Sequence		Y	L	E	K	A	C	V	I	H	R	D	L	A	A	R	N	C	L	V	.	G	E	N	Q	V	I	K	V	S	D	F	G	M	T	R	F	V	L	D	D	Q	Y	T	S	S	T	G	T	K	F	P	V	K	W	A	S	P	E	V	F
Query Conservation																					.
Alig confidence																					.																			.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																								.	.	.	.	.	.	.	.	.	.	.
Template Sequence		Y	L	H	D	N	Q	I	V	H	R	D	I	K	G	D	N	V	L	I	N	T	Y	S	G	V	L	K	I	S	D	F	G	T	S	K	R	L	T	.	.	.	.	.	.	.	.	.	.	.	G	T	L	Q	Y	M	A	P	E	I	I
Template Known Secondary structure						T	T				S			S	G	G	G					T	T	T									S	S						.	.	.	.	.	.	.	.	.	.	.			G	G	G
Template Predicted Secondary structure																																								.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		793	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830												.	.	.	.	.	.	.	.	.	840	.
		536	.	.	.			540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.			.	580	.	.	.	.	.	.	.	.	.	590	.
Predicted Secondary structure						.	.																																								.	.
Query SS confidence						.	.																																								.	.
Query Sequence		S	F	S	R	.	.	Y	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	V	F	S	E	G	K	I	P	Y	E	N	R	S	N	S	E	V	V	E	D	I	S	T	.	.	G	F	R	L	Y	K	P	R	L	A	S	C	H
Query Conservation						.	.																																								.	.
Alig confidence						.	.																				.																				.	.
Template Conservation																											.
Template Sequence		D	K	G	P	R	G	Y	G	K	A	A	D	I	W	S	L	G	C	T	I	I	E	M	A	T	.	G	K	P	P	F	Y	E	L	G	E	P	Q	A	A	M	F	K	V	G	M	F	K	V	H	P	E	I	P	E	S	M	S	A	E
Template Known Secondary structure					G	G	G		S																		.	S	S		T	T	G	G	G		S												T							T	T	S
Template Predicted Secondary structure																											.
Template SS confidence
		852	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.		.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
		592	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	Y	Q	I	M	N	H	C	W	K	E	K	P	E	D	R	P	P	F	S	Q	L	L	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	K	A	F	I	L	K	C	F	E	P	D	P	D	K	R	A	C	A	N	D	L	L	V
Template Known Secondary structure										T		S		T	T	T	S								T
Template Predicted Secondary structure
Template SS confidence
		911	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D