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Job DescriptionQ03526
Confidence100.00%DateWed Jul 10 14:09:50 BST 2013
Rank118Aligned Residues333
% Identity21%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å
Model Dimensions (Å)X:58.271 Y:66.184 Z:45.026

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20.........30.........40.........50.........60.
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Query Sequence  NNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDRHGKKRTLKGSIELSRIK
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Template Sequence  DVAIVKEGWLHKRGEYIKT. . . . . WRPRYFLLKNDGTFIGYKERPQDVEA. . PLNNFSVA
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GGGB
T
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   3......10.........20. ........30.........40....... ..50.....
 
   62.......70.........80.........90. ........100.........110.........120
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Query Sequence  CVEIVKSDISIPCHYKYPFQTLVYLQVVHD. NYLLYVFAPDCESRQRWVLTLKEETRNNN
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Template Sequence  QCQLMKTER. . . . . . . . . . PRPNTFIIRCLQWTTVIERTFTPEEREEWTTAIQTVADGLK
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TTGGGT
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   5960....... ..70.........80.........90.........100........
 
   121........130.........140.........150.........160.........170.........180
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Query Sequence  SLVSKYHPNFWMDGRWRCCSQLEKPAVGCAPYDPSKNASKKPLPPTPEDNRRSFQEPEET
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Template Sequence  KQVTM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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T.......................................................
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   112....
 
   181........190.........200.........210.........220.........230.........240
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Query Sequence  LVIALYDYQTNDPQELALRCDEEYYLLDSSEIHWWRVQDKNGHEGYAPSSYLVEKSPNNL
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   241........250.........260.........270.........280.........290.........300
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Query Sequence  ETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKAIISENPCIKHYHI
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   301........310.........320.........330.........340.........350.........360
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Query Sequence  KETNDSPKRYYVAEKYVFDSIPLLIQYHQYNGGGLVTRLRYPVCSWRQKAPVTAGLRYGK
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   361........370.........380......... 390.........400.........410.........
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Query Sequence  WVIQPSELTFVQEIGSGQFGLVHLGYWLN. KDKVAIKTIQEGAMSEEDFIEEAEVMMKLS
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Template Sequence  . . . . . NEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILK. . . . . . KEVIVANRVLQNSR
Template Known Secondary structure  .....TSTTTTT

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   148.150.........160.........170.........180.. .......190......
 
   420.........430.........440.........450.........460.........470.........
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Query Sequence  HPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRSQRGLFAAETLLGMCLDVCEGMAYLE
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Template Sequence  HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERV. FSEDRARFYGAEIVSALDYLH
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TTB


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   207..210.........220.........230.........240.... .....250.........260.....
 
   480 .........490.........500.........510.........520.........530........
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Query Sequence  K. ACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFS
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Template Sequence  SEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEPE. . . . . . . . . . . . . . . YLAPEVLEDN
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GGG
TTS




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   266...270.........280.........290.........300 .........310
 
   539540.........550.........560.........570.........580.........590........
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Query Sequence  RYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASCHVYQIMNH
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Template Sequence  DYGRAVDWWGLGVVMYEMMC. GRLPFYNQDHEKLFELILMEE. IRFPRTLGPEAKSLLSG
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T.SS
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   325....330.........340.... .....350.........360..... ....370.........380..
 
   599600....... ..610.....
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Query Sequence  CWKEKPEDR. . . . . PPFSQLLS
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Template Conservation   
  

  
     

  
 
 
Template Sequence  LLKKDPKQRLGGGSEDAKEIMQ
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SSTTTSTT
STTTT
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   383......390.........400....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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