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Job DescriptionQ03526
Confidence100.00%DateWed Jul 10 14:09:50 BST 2013
Rank92Aligned Residues241
% Identity57%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   358.360.........370.........380.........390.........400.........410.......
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Query Sequence  YGKWVIQPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIQEGAMSEEDFIEEAEVMMK
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Template Sequence  YGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIK. . . . . . . EFIEEAKVMMN
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GGGB

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TT
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   392.......400.........410.........420.........430... ......440....
 
   418.420.........430.........440.........450.........460.........470.......
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Query Sequence  LSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRSQRGLFAAETLLGMCLDVCEGMAY
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Template Sequence  LSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEY
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   452.......460.........470.........480.........490.........500.........510.
 
   478.480.........490.........500.........510.........520.........530.......
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Query Sequence  LEKACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSF
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Template Sequence  LESKQFLHRDLAARNCLVNDQGVVKVSDFGFPV. . . . . . . . . . . . . . . . . RWSPPEVLMY
Template Known Secondary structure  TT


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SGGG
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   512.......520.........530.........540.... .....550....
 
   538.540.........550.........560.........570.........580.........590.......
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Query Sequence  SRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASCHVYQIMN
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Template Sequence  SKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMY
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TTTTS
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TTS
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   572.......580.........590.........600.........610.........620.........630.
 
   598.600.........610.........620..
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Query Sequence  HCWKEKPEDRPPFSQLLSQLAEIAE
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Template Sequence  SCWHEKADERPTFKILLSNILDVMD
Template Known Secondary structure  TT
SSGGGS

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   632.......640.........650......
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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